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The map label for this gene is serC [H]

Identifier: 73542261

GI number: 73542261

Start: 2821266

End: 2822417

Strand: Reverse

Name: serC [H]

Synonym: Reut_A2576

Alternate gene names: 73542261

Gene position: 2822417-2821266 (Counterclockwise)

Preceding gene: 73542262

Following gene: 73542260

Centisome position: 74.15

GC content: 62.15

Gene sequence:

>1152_bases
ATGAACGATCCACAGACTCCCGCCCTCGCCGGCATGCAGCGTGCATTGGCCGAACGCGTCTTCAACTTCTCCCCGGGACC
CGCCACGCTGCCCGCCGAAGTGCTGCAACAGGCCGCAGAAGAGATGCTGTCATGGCATGGGACGGGCGTGTCGGTCATGG
AGATGAGCCACCGCAGCCGCGAGTTCGAAGGCATTCTTGCCGAAACGACCGCGGATCTGCGTGAACTGCTCAAGATTCCA
AAGAACTTCCGCATTCTGTTCCTGCAGGGCGGCGCCATCGGCGAGAACGCGATCGTGCCGCTGAACCTGATGCGGCTGCG
CAATGCCGATCGCCCCAAGGCAGACTTCGTGGTGACCGGCTCGTGGTCTATCAAGACCGAGCAGGAAACGCGACGCTACG
GCGAGGTAAACATCGCAGCATCGAGCGCCGACCGGAAGTTTCACGATATCCCCGACGTGGCCGGCTGGAAGCTGTCCGAT
GACGCTGCCTACGTGCATCTCTGCACCAACGAGACGATCGGCGGCGTGGAGTTCCACGAGGTTCCGGATATCGGGCAGGA
CAAGGGCCGCGTCGTGGTGGCCGACGCATCGAGCCACATCCTGTCGCGCCCAGTGGACTGGTCGCGCGTGCAGGTGATGT
ATGGCGGTGCACAGAAGAATATCGGGCCCGCTGGCGTGACGATCGTGATCGTGCGAGAAGACCTGCTGGGCCATGCTCAT
CCGCTATGCCCGTCGGCGTTTAACTGGCGTATCGTCGCCGAGCATGACTCGATGTACAACACGCCGCCGACGTACGCCAT
CTACATCGCGGGGCTGGTCTTCAAGTGGCTCAAGCGCCAAGGCGGAGTGCCGGCGATCGAGCAACGCAATATCGCCAAGG
CGAAGGCACTGTACGACTTCCTTGACCAGAGCGATTTCTATCGCAATGAGATCGACCCGAACTGCCGTTCGCGCATGAAC
GTGCCGTTCTTCCTCGCTGACGAGACCCGCAACGAGGCATTCCTGCAGCAGGCCCGCGCCCATGGCCTGCTGCAACTCAA
GGGCCACAAGTCCGTGGGCGGCATGCGCGCCAGCATCTACAACGCCATGCCGATCGAGGGCGTGTATGCGCTGATCGATT
TCATGCGTGAGTTCGAGCGCAACGCTGCCTGA

Upstream 100 bases:

>100_bases
GTGCAGGTCCTGCGCCCGCCCGCATCGCCCAACGGGATGCGGGTTTGAGGGATAATGGCTGCTTGGGGTATCCCCGGCAG
CCATTTTTCTTTTCCAGTTC

Downstream 100 bases:

>100_bases
CGGCGCTGCGGCGGACAGCCGCGCGCGAACGGCGCGCGGCATTGTTTTATTCTCAGGCCCTCCCTGCGGAGCGGCCCAAC
CGGTTCCTGCAAATGACAAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNDPQTPALAGMQRALAERVFNFSPGPATLPAEVLQQAAEEMLSWHGTGVSVMEMSHRSREFEGILAETTADLRELLKIP
KNFRILFLQGGAIGENAIVPLNLMRLRNADRPKADFVVTGSWSIKTEQETRRYGEVNIAASSADRKFHDIPDVAGWKLSD
DAAYVHLCTNETIGGVEFHEVPDIGQDKGRVVVADASSHILSRPVDWSRVQVMYGGAQKNIGPAGVTIVIVREDLLGHAH
PLCPSAFNWRIVAEHDSMYNTPPTYAIYIAGLVFKWLKRQGGVPAIEQRNIAKAKALYDFLDQSDFYRNEIDPNCRSRMN
VPFFLADETRNEAFLQQARAHGLLQLKGHKSVGGMRASIYNAMPIEGVYALIDFMREFERNAA

Sequences:

>Translated_383_residues
MNDPQTPALAGMQRALAERVFNFSPGPATLPAEVLQQAAEEMLSWHGTGVSVMEMSHRSREFEGILAETTADLRELLKIP
KNFRILFLQGGAIGENAIVPLNLMRLRNADRPKADFVVTGSWSIKTEQETRRYGEVNIAASSADRKFHDIPDVAGWKLSD
DAAYVHLCTNETIGGVEFHEVPDIGQDKGRVVVADASSHILSRPVDWSRVQVMYGGAQKNIGPAGVTIVIVREDLLGHAH
PLCPSAFNWRIVAEHDSMYNTPPTYAIYIAGLVFKWLKRQGGVPAIEQRNIAKAKALYDFLDQSDFYRNEIDPNCRSRMN
VPFFLADETRNEAFLQQARAHGLLQLKGHKSVGGMRASIYNAMPIEGVYALIDFMREFERNAA
>Mature_383_residues
MNDPQTPALAGMQRALAERVFNFSPGPATLPAEVLQQAAEEMLSWHGTGVSVMEMSHRSREFEGILAETTADLRELLKIP
KNFRILFLQGGAIGENAIVPLNLMRLRNADRPKADFVVTGSWSIKTEQETRRYGEVNIAASSADRKFHDIPDVAGWKLSD
DAAYVHLCTNETIGGVEFHEVPDIGQDKGRVVVADASSHILSRPVDWSRVQVMYGGAQKNIGPAGVTIVIVREDLLGHAH
PLCPSAFNWRIVAEHDSMYNTPPTYAIYIAGLVFKWLKRQGGVPAIEQRNIAKAKALYDFLDQSDFYRNEIDPNCRSRMN
VPFFLADETRNEAFLQQARAHGLLQLKGHKSVGGMRASIYNAMPIEGVYALIDFMREFERNAA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=365, Percent_Identity=46.8493150684932, Blast_Score=348, Evalue=3e-96,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=42.5, Blast_Score=300, Evalue=2e-81,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=53.2967032967033, Blast_Score=388, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17506897, Length=367, Percent_Identity=43.3242506811989, Blast_Score=312, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=40.6735751295337, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21356589, Length=367, Percent_Identity=47.4114441416894, Blast_Score=345, Evalue=2e-95,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 42650; Mature: 42650

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPQTPALAGMQRALAERVFNFSPGPATLPAEVLQQAAEEMLSWHGTGVSVMEMSHRSR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EFEGILAETTADLRELLKIPKNFRILFLQGGAIGENAIVPLNLMRLRNADRPKADFVVTG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHCCCCCCCCCEEEEC
SWSIKTEQETRRYGEVNIAASSADRKFHDIPDVAGWKLSDDAAYVHLCTNETIGGVEFHE
CEEECCHHHHHHCCCEEEEECCCCCCHHCCCCCCCCEECCCCEEEEEECCCCCCCEEECC
VPDIGQDKGRVVVADASSHILSRPVDWSRVQVMYGGAQKNIGPAGVTIVIVREDLLGHAH
CCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECHHHCCCC
PLCPSAFNWRIVAEHDSMYNTPPTYAIYIAGLVFKWLKRQGGVPAIEQRNIAKAKALYDF
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHH
LDQSDFYRNEIDPNCRSRMNVPFFLADETRNEAFLQQARAHGLLQLKGHKSVGGMRASIY
HCCCHHHHCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHH
NAMPIEGVYALIDFMREFERNAA
CCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDPQTPALAGMQRALAERVFNFSPGPATLPAEVLQQAAEEMLSWHGTGVSVMEMSHRSR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EFEGILAETTADLRELLKIPKNFRILFLQGGAIGENAIVPLNLMRLRNADRPKADFVVTG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHCCCCCCCCCEEEEC
SWSIKTEQETRRYGEVNIAASSADRKFHDIPDVAGWKLSDDAAYVHLCTNETIGGVEFHE
CEEECCHHHHHHCCCEEEEECCCCCCHHCCCCCCCCEECCCCEEEEEECCCCCCCEEECC
VPDIGQDKGRVVVADASSHILSRPVDWSRVQVMYGGAQKNIGPAGVTIVIVREDLLGHAH
CCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECHHHCCCC
PLCPSAFNWRIVAEHDSMYNTPPTYAIYIAGLVFKWLKRQGGVPAIEQRNIAKAKALYDF
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHH
LDQSDFYRNEIDPNCRSRMNVPFFLADETRNEAFLQQARAHGLLQLKGHKSVGGMRASIY
HCCCHHHHCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHH
NAMPIEGVYALIDFMREFERNAA
CCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA