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The map label for this gene is hldE [H]

Identifier: 73542249

GI number: 73542249

Start: 2809099

End: 2810046

Strand: Reverse

Name: hldE [H]

Synonym: Reut_A2564

Alternate gene names: 73542249

Gene position: 2810046-2809099 (Counterclockwise)

Preceding gene: 73542250

Following gene: 73542248

Centisome position: 73.82

GC content: 65.82

Gene sequence:

>948_bases
ATGGGTATGAATCAAATTTCGCAGGATCAGATCGGCCAGGCGCGCATCCTGGTGGTCGGCGACATGATGCTGGACCGCTA
CTGGTTCGGCGACGTCGAGCGCATTTCGCCGGAGGCGCCGGTACCGGTCGTCCAGATCAAGCGCAGCGATGAGCGCCTGG
GCGGCGCCGCCAACGTGGCGCGCAACTCGGCCGCGCTCGGTGCGCAGGTCGGCATGCTCGGCGTCGTCGGTGACGATGAG
CCTGGCCGCACCATCGAATCGTTGCTGTCGGCGTGCAAAGTCCAGCCGTACCTGCACCGCGACGCCAGCGTCAACACGAC
GATCAAGCTGCGCGTGCTCGCGCACCAGCAGCAGTTGCTGCGGGTGGATTTCGAGAACCCGCCGACGCATGAGGTCTTGC
TGTCGGTGCTCGAAGGTTTCCAGGAACTCGTGAAGCAGTACGAGGTACTGGTGCTGTCGGACTATGGCAAGGGCGGGCTG
ACCCACGTGGGCCGCATGGTCGAGGCCGGCCGCGCGGCCGGGCGGATGGTGCTCGTCGATCCGAAGGGCGACGACTATTC
GCGCTACCGTGGTGCCACGCTGATCACTCCCAACCGCGCCGAGATCCGGCGCGTCGTGGGCGCCTGGAAAAGCGAACAGG
ACCTCACCGCGCGCGCCCAGAACCTGCGGCGTGACTTGCAGCTCGAAGCGCTGCTGCTCACCCGTTCGGAAGAGGGTATG
ACTCTTTACACGGAGGCTGAGGTACTGCACGTCTCGGCACAGGCGCGGGAAGTCTATGATGTATCAGGTGCCGGCGATAC
CGTGATCGCCACGCTGGCGACCATGCTGGCGGCCGGCGTGTCGCTGAAGCAGGCGGTGCAGTTCGCCAACCGCGCTGGCG
GCATTGTCGTGGGCAAGCTGGGTACTGCCGTCGTCAGCTACCCGGAACTGTTCGGCGCTGCCGGCTGA

Upstream 100 bases:

>100_bases
GGCCGGCATCGAATACCACGCGATCGGGCGATCGGCCGCGAAGCGCTGAACGCATCAGCAGCGCGCCTGTCCGAAGACGG
ACAGGCTTGCCGGAGGAATC

Downstream 100 bases:

>100_bases
TCGCCTGTGTCTTCCGGCGCGCCCTGTTGAACTCTCTGTCGGACCGATCATGACCATCATCGTCACCGGCGCTGCAGGAT
TCATCGGCAGCAACCTCGTC

Product: D-alpha,beta-D-heptose 7-phosphate 1-kinase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGMNQISQDQIGQARILVVGDMMLDRYWFGDVERISPEAPVPVVQIKRSDERLGGAANVARNSAALGAQVGMLGVVGDDE
PGRTIESLLSACKVQPYLHRDASVNTTIKLRVLAHQQQLLRVDFENPPTHEVLLSVLEGFQELVKQYEVLVLSDYGKGGL
THVGRMVEAGRAAGRMVLVDPKGDDYSRYRGATLITPNRAEIRRVVGAWKSEQDLTARAQNLRRDLQLEALLLTRSEEGM
TLYTEAEVLHVSAQAREVYDVSGAGDTVIATLATMLAAGVSLKQAVQFANRAGGIVVGKLGTAVVSYPELFGAAG

Sequences:

>Translated_315_residues
MGMNQISQDQIGQARILVVGDMMLDRYWFGDVERISPEAPVPVVQIKRSDERLGGAANVARNSAALGAQVGMLGVVGDDE
PGRTIESLLSACKVQPYLHRDASVNTTIKLRVLAHQQQLLRVDFENPPTHEVLLSVLEGFQELVKQYEVLVLSDYGKGGL
THVGRMVEAGRAAGRMVLVDPKGDDYSRYRGATLITPNRAEIRRVVGAWKSEQDLTARAQNLRRDLQLEALLLTRSEEGM
TLYTEAEVLHVSAQAREVYDVSGAGDTVIATLATMLAAGVSLKQAVQFANRAGGIVVGKLGTAVVSYPELFGAAG
>Mature_314_residues
GMNQISQDQIGQARILVVGDMMLDRYWFGDVERISPEAPVPVVQIKRSDERLGGAANVARNSAALGAQVGMLGVVGDDEP
GRTIESLLSACKVQPYLHRDASVNTTIKLRVLAHQQQLLRVDFENPPTHEVLLSVLEGFQELVKQYEVLVLSDYGKGGLT
HVGRMVEAGRAAGRMVLVDPKGDDYSRYRGATLITPNRAEIRRVVGAWKSEQDLTARAQNLRRDLQLEALLLTRSEEGMT
LYTEAEVLHVSAQAREVYDVSGAGDTVIATLATMLAAGVSLKQAVQFANRAGGIVVGKLGTAVVSYPELFGAAG

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=317, Percent_Identity=48.5804416403785, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 34065; Mature: 33934

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMNQISQDQIGQARILVVGDMMLDRYWFGDVERISPEAPVPVVQIKRSDERLGGAANVA
CCCCCCCHHHCCCEEEEEEEHHHHHHHHCCCHHHCCCCCCCCEEEEECCHHHCCCHHHHH
RNSAALGAQVGMLGVVGDDEPGRTIESLLSACKVQPYLHRDASVNTTIKLRVLAHQQQLL
HCCHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEEECHHHHH
RVDFENPPTHEVLLSVLEGFQELVKQYEVLVLSDYGKGGLTHVGRMVEAGRAAGRMVLVD
EEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEC
PKGDDYSRYRGATLITPNRAEIRRVVGAWKSEQDLTARAQNLRRDLQLEALLLTRSEEGM
CCCCCHHHHCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCC
TLYTEAEVLHVSAQAREVYDVSGAGDTVIATLATMLAAGVSLKQAVQFANRAGGIVVGKL
EEEEEEEEEEEEHHHHHEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECH
GTAVVSYPELFGAAG
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
GMNQISQDQIGQARILVVGDMMLDRYWFGDVERISPEAPVPVVQIKRSDERLGGAANVA
CCCCCCHHHCCCEEEEEEEHHHHHHHHCCCHHHCCCCCCCCEEEEECCHHHCCCHHHHH
RNSAALGAQVGMLGVVGDDEPGRTIESLLSACKVQPYLHRDASVNTTIKLRVLAHQQQLL
HCCHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEEECHHHHH
RVDFENPPTHEVLLSVLEGFQELVKQYEVLVLSDYGKGGLTHVGRMVEAGRAAGRMVLVD
EEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEC
PKGDDYSRYRGATLITPNRAEIRRVVGAWKSEQDLTARAQNLRRDLQLEALLLTRSEEGM
CCCCCHHHHCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCC
TLYTEAEVLHVSAQAREVYDVSGAGDTVIATLATMLAAGVSLKQAVQFANRAGGIVVGKL
EEEEEEEEEEEEHHHHHEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECH
GTAVVSYPELFGAAG
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA