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The map label for this gene is udg [H]

Identifier: 73542250

GI number: 73542250

Start: 2810098

End: 2811471

Strand: Reverse

Name: udg [H]

Synonym: Reut_A2565

Alternate gene names: 73542250

Gene position: 2811471-2810098 (Counterclockwise)

Preceding gene: 73542251

Following gene: 73542249

Centisome position: 73.86

GC content: 63.54

Gene sequence:

>1374_bases
ATGAAAGTCACCATTATTGGCAGTGGCTATGTTGGCCTCGTTACCGGCGCGTGCCTGGCCGAACTCGGCAACGATGTGTT
CTGCCTCGACGTCGACGAAAAGAAGATTGCCTTGCTCAACGCCGGCGGTGTGCCGATCTACGAGCCGGGGCTTCAGGAAA
TCATCCAGCGCAATCGCGCGGCCGGGCGGCTGACGTTCTCGACCGATGTGGCGGCGAGCGTCGAGCACGCCGATGTGCAG
TTCATCGCCGTTGGCACCCCGCCCGATGAAGACGGCTCGGCGGATCTGAAGTATGTGCTTGCGGCGGCGCGCAATATCGG
CCGCCATATGACCGGCTTCAAGGTCGTCGTCGACAAGTCCACGGTGCCGGTCGGCACGGGCGACCGCGTAGCCGCTGTGA
TTCGCGAGGAGCTTGCCGCGCGCGGCCTGGAGGACCTGCAGTATTCCGTGGTGTCGAACCCGGAATTCCTCAAGGAAGGC
GCTGCGGTCGAAGACTTCATGCGTCCGGATCGCATCGTGCTCGGCTGCAGCGCCGACGCTGCCGGGCGCCACGCGCAGGC
CACCATGCGGCAGCTCTATGCGCCATTCAACCGCAACCACGAACGCACCTTCTACATGGATGTGCGCTCGGCGGAATTCA
CCAAGTACGCCGCCAACTCCATGCTGGCCACGCGTATTTCATTCATGAACGAACTGGCCAATCTGGCCGACGAGGTTGGT
GCCGACATCGAACTCGTTCGCATGGGCATCGGCTCGGATCCGCGTATCGGCTACAGTTTTTTGTATGCGGGTGCAGGCTA
TGGCGGTTCTTGCTTCCCGAAGGATGTGCAGGCGCTGATGCGCACGGCGTCGGACCACGGCAAGCCGATGCGCGTGCTGG
AGGCTGTCGAAGCCGTGAACGGTGCTCAGAAGCAGGTGCTCGGCGACAAGGTGCTGCGCCGGTTTGGCGATGACCTGAGC
GGCCACACCTTTGCCATCTGGGGGCTGGCGTTCAAGCCGAACACCGACGATATGCGCGAAGCGCCGTCCCGCGTGCTCGC
GCGCGAACTGGTCTCGCGCGGGGCAACGCTGCGCATGCACGATCCGGTGTCCATGGAAGAGGCGAGGCGCGTGCTGGAAA
CGGATCTCGCCGACATTCCGGGTGGTATCGACCGGCTCAGTTTCCACGCTGCCCAGATGGAGACCCTCGATGGTGCCGAC
GCGCTGGTGATCGTGACGGAATGGAAGGTCTTCCGCAGCCCGGATTTCGAGCAGATCAAGCGGCGCCTGAAGACGCCGGT
GATCTTCGATGGACGTAACCTGTACGAGCCGGAAGCCATGGCGCAGGCCGGCATCGAATACCACGCGATCGGGCGATCGG
CCGCGAAGCGCTGA

Upstream 100 bases:

>100_bases
GCAATGTCCCGGCTGCAACCGCTGGGAGACCTATGCGCCCCGGCGATCCGAAGCGCTCGGCTGACCAGGCCGCCACGCGA
ACTAATTTCATGTAAATGCT

Downstream 100 bases:

>100_bases
ACGCATCAGCAGCGCGCCTGTCCGAAGACGGACAGGCTTGCCGGAGGAATCATGGGTATGAATCAAATTTCGCAGGATCA
GATCGGCCAGGCGCGCATCC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKVTIIGSGYVGLVTGACLAELGNDVFCLDVDEKKIALLNAGGVPIYEPGLQEIIQRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVAAVIREELAARGLEDLQYSVVSNPEFLKEG
AAVEDFMRPDRIVLGCSADAAGRHAQATMRQLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRMGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASDHGKPMRVLEAVEAVNGAQKQVLGDKVLRRFGDDLS
GHTFAIWGLAFKPNTDDMREAPSRVLARELVSRGATLRMHDPVSMEEARRVLETDLADIPGGIDRLSFHAAQMETLDGAD
ALVIVTEWKVFRSPDFEQIKRRLKTPVIFDGRNLYEPEAMAQAGIEYHAIGRSAAKR

Sequences:

>Translated_457_residues
MKVTIIGSGYVGLVTGACLAELGNDVFCLDVDEKKIALLNAGGVPIYEPGLQEIIQRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVAAVIREELAARGLEDLQYSVVSNPEFLKEG
AAVEDFMRPDRIVLGCSADAAGRHAQATMRQLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRMGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASDHGKPMRVLEAVEAVNGAQKQVLGDKVLRRFGDDLS
GHTFAIWGLAFKPNTDDMREAPSRVLARELVSRGATLRMHDPVSMEEARRVLETDLADIPGGIDRLSFHAAQMETLDGAD
ALVIVTEWKVFRSPDFEQIKRRLKTPVIFDGRNLYEPEAMAQAGIEYHAIGRSAAKR
>Mature_457_residues
MKVTIIGSGYVGLVTGACLAELGNDVFCLDVDEKKIALLNAGGVPIYEPGLQEIIQRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVAAVIREELAARGLEDLQYSVVSNPEFLKEG
AAVEDFMRPDRIVLGCSADAAGRHAQATMRQLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRMGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASDHGKPMRVLEAVEAVNGAQKQVLGDKVLRRFGDDLS
GHTFAIWGLAFKPNTDDMREAPSRVLARELVSRGATLRMHDPVSMEEARRVLETDLADIPGGIDRLSFHAAQMETLDGAD
ALVIVTEWKVFRSPDFEQIKRRLKTPVIFDGRNLYEPEAMAQAGIEYHAIGRSAAKR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=474, Percent_Identity=35.8649789029536, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI296040438, Length=376, Percent_Identity=35.6382978723404, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI296040443, Length=320, Percent_Identity=34.6875, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1788340, Length=407, Percent_Identity=28.009828009828, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI48994968, Length=426, Percent_Identity=28.6384976525822, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=467, Percent_Identity=35.5460385438972, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=34.475374732334, Blast_Score=261, Evalue=9e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49816; Mature: 49816

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTIIGSGYVGLVTGACLAELGNDVFCLDVDEKKIALLNAGGVPIYEPGLQEIIQRNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCC
AGRLTFSTDVAASVEHADVQFIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKS
CCEEEEECCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVAAVIREELAARGLEDLQYSVVSNPEFLKEGAAVEDFMRPDRIVLGCSADA
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCHHHHCCCCCEEEECCCCC
AGRHAQATMRQLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRMGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASDHGKPMRVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GAQKQVLGDKVLRRFGDDLSGHTFAIWGLAFKPNTDDMREAPSRVLARELVSRGATLRMH
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEC
DPVSMEEARRVLETDLADIPGGIDRLSFHAAQMETLDGADALVIVTEWKVFRSPDFEQIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHH
RRLKTPVIFDGRNLYEPEAMAQAGIEYHAIGRSAAKR
HHHCCCEEECCCCCCCCHHHHHCCCEEEECCHHHCCC
>Mature Secondary Structure
MKVTIIGSGYVGLVTGACLAELGNDVFCLDVDEKKIALLNAGGVPIYEPGLQEIIQRNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCC
AGRLTFSTDVAASVEHADVQFIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKS
CCEEEEECCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVAAVIREELAARGLEDLQYSVVSNPEFLKEGAAVEDFMRPDRIVLGCSADA
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCHHHHCCCCCEEEECCCCC
AGRHAQATMRQLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRMGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASDHGKPMRVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GAQKQVLGDKVLRRFGDDLSGHTFAIWGLAFKPNTDDMREAPSRVLARELVSRGATLRMH
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEC
DPVSMEEARRVLETDLADIPGGIDRLSFHAAQMETLDGADALVIVTEWKVFRSPDFEQIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHH
RRLKTPVIFDGRNLYEPEAMAQAGIEYHAIGRSAAKR
HHHCCCEEECCCCCCCCHHHHHCCCEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]