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The map label for this gene is opuCB [H]

Identifier: 73542179

GI number: 73542179

Start: 2733969

End: 2734619

Strand: Reverse

Name: opuCB [H]

Synonym: Reut_A2494

Alternate gene names: 73542179

Gene position: 2734619-2733969 (Counterclockwise)

Preceding gene: 73542180

Following gene: 73542178

Centisome position: 71.84

GC content: 64.67

Gene sequence:

>651_bases
ATGGACTTGCTGACCTACCTCCAACATAGCTGGCCGACGCTGCTGAAGCTCACTGCCGAGCATCTGGCGCTCGTCGGCTC
GGCCGTGGGCATGGCGATCCTGATAGGCGTGCCCCTGGGCATTGCGATCACGCGCTTCCGCTGGCTGGCCACGCCGGTGC
TGACGCTCGCGACGATCGTGCTGACGCTGCCGTCGATCGCGCTGTTCGGGCTGATGATCCCGATCTTCGCGCGCTTCGGG
CATGCGCTGGGCTATCTGCCCGCCGTGACCGCGGTGTTTCTGTATTCGCTGCTGCCGATCATGCGCAACACCTACACGGC
GCTGGTCAATATCGACCCCGGCATCCAGGAAGCCGGGCGGGGCATCGGCATGACCACGTGGCAGCGCATGCGCCGCGTGG
ACCTGCCGCTGGCCGTGCCCGTGATCCTGGGCGGCGTACGTACCGCCGTGGTGATGAACATCGGCGTGGCCACCATTGCC
GCCATCATCGGCGCAGGTGGTCTTGGGGTGCTGATCCTGCAAGCGATCAGCCAGAGCAATATGAGCAAGCTGGCCGTGGG
CGCGATCCTGGTCAGCGTGCTCGCCATCGTGGCGGATGCCTTCCTGCAATGGTTGCAGAAGGTGTTGACGCCAAAAGGAA
TCCGACTATGA

Upstream 100 bases:

>100_bases
ATGACCGAGATGAACTACCAGGTGGACATCGGCCAGCAGCCGGTGGACAAGGTGGCCGCAGACTTCCTGCGCAGCCATGG
CCTGATCTGAGGAGGCACGC

Downstream 100 bases:

>100_bases
TCGAACTCGACCGACTCACCAAGGCCTTCCCCCAGAAAGACGGCACTGAAGTGCGGGCAGTGGATGCTGTCTCGCTGACA
GTGCCACGCGGGGAAATCTG

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MDLLTYLQHSWPTLLKLTAEHLALVGSAVGMAILIGVPLGIAITRFRWLATPVLTLATIVLTLPSIALFGLMIPIFARFG
HALGYLPAVTAVFLYSLLPIMRNTYTALVNIDPGIQEAGRGIGMTTWQRMRRVDLPLAVPVILGGVRTAVVMNIGVATIA
AIIGAGGLGVLILQAISQSNMSKLAVGAILVSVLAIVADAFLQWLQKVLTPKGIRL

Sequences:

>Translated_216_residues
MDLLTYLQHSWPTLLKLTAEHLALVGSAVGMAILIGVPLGIAITRFRWLATPVLTLATIVLTLPSIALFGLMIPIFARFG
HALGYLPAVTAVFLYSLLPIMRNTYTALVNIDPGIQEAGRGIGMTTWQRMRRVDLPLAVPVILGGVRTAVVMNIGVATIA
AIIGAGGLGVLILQAISQSNMSKLAVGAILVSVLAIVADAFLQWLQKVLTPKGIRL
>Mature_216_residues
MDLLTYLQHSWPTLLKLTAEHLALVGSAVGMAILIGVPLGIAITRFRWLATPVLTLATIVLTLPSIALFGLMIPIFARFG
HALGYLPAVTAVFLYSLLPIMRNTYTALVNIDPGIQEAGRGIGMTTWQRMRRVDLPLAVPVILGGVRTAVVMNIGVATIA
AIIGAGGLGVLILQAISQSNMSKLAVGAILVSVLAIVADAFLQWLQKVLTPKGIRL

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=210, Percent_Identity=39.5238095238095, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788451, Length=205, Percent_Identity=38.5365853658537, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1789033, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22923; Mature: 22923

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLTYLQHSWPTLLKLTAEHLALVGSAVGMAILIGVPLGIAITRFRWLATPVLTLATIV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLPSIALFGLMIPIFARFGHALGYLPAVTAVFLYSLLPIMRNTYTALVNIDPGIQEAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCC
GIGMTTWQRMRRVDLPLAVPVILGGVRTAVVMNIGVATIAAIIGAGGLGVLILQAISQSN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
MSKLAVGAILVSVLAIVADAFLQWLQKVLTPKGIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLLTYLQHSWPTLLKLTAEHLALVGSAVGMAILIGVPLGIAITRFRWLATPVLTLATIV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLPSIALFGLMIPIFARFGHALGYLPAVTAVFLYSLLPIMRNTYTALVNIDPGIQEAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCC
GIGMTTWQRMRRVDLPLAVPVILGGVRTAVVMNIGVATIAAIIGAGGLGVLILQAISQSN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
MSKLAVGAILVSVLAIVADAFLQWLQKVLTPKGIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]