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The map label for this gene is uup-A [H]

Identifier: 73542046

GI number: 73542046

Start: 2602668

End: 2604596

Strand: Reverse

Name: uup-A [H]

Synonym: Reut_A2360

Alternate gene names: 73542046

Gene position: 2604596-2602668 (Counterclockwise)

Preceding gene: 73542049

Following gene: 73542044

Centisome position: 68.42

GC content: 67.19

Gene sequence:

>1929_bases
ATGGCCCTGTTTTCCATTAACGATGCCCAGCTTGCTTTCGGGCACGTGGCCTTGCTCGACCACACCGATTTTTCGCTGGA
AGCCGGCGAGCGTGTCGGCCTGATTGGCCGCAACGGCTCGGGCAAATCCTCGCTGCTGAAGATCGTGGCGGGGCTGGCGG
CGCCGGATGACGGCCTGATTGCGCGCCAGTCGGGCGTGACCTCGGCCTACGTGCCGCAAGAGCCGCAATTCGATCCGGGC
ATCACCGTGTTCGATGCCGTGTCGCAGGGCATGGGCCAGGCGCATGACCTGCTGATGCGTTACGAGGCCGCCGCCGAGCG
GCTGGCCGACAGCCATGACGAAGCCGCGCTGGCCGAACTGCACCGGCTGCAGTCGGAGCTCGATGCCGCCGGCGCCTGGC
ATCTGCGCACCCGCGTGGAAACCACGCTGGCCCGGCTGGGGCTCGATCCGCATACGCCCGTCGATGCGCTGTCCGGGGGC
TTGCAGAAGCGCGTGGCGCTTGCTCAGGGTCTGGTCGCGGAACCGGACATCCTGCTGCTGGACGAGCCGACCAACCACCT
CGACGTGGAAGCGATCCGCTGGCTCGAAGACCTGTTGCTCGGTTTCCGCGGCAGCGTGCTGCTGATCACCCACGACCGCG
CGTTCCTGGACCGCGTGGCGACCCGTATCGTTGAACTCGACCGCGGCCGCCTGCTGTCTTTCCCGGGCAACTTTGCGGCC
TACCAGGCCCGCAAGGAAGAACTGCTGGCCGCCGAGCAGGTGGAGCAGGCCAAGTTCGACAAGCTGCTCGCGCAGGAAGA
AGTGTGGATCCGCAAGGGCGTCGAGGCACGCCGCACGCGCAGCGTGGCGCGTATCCAGCGGCTCGTGGCGATGCGCTCCG
AGCGCGCGGCGCGGCGTGAGGCACAGGGCAACGTCAAGCTGGAGGTGTCCCAGGCCGACCGCTCCGGCAAGATCGTGGCC
GAGCTGATCGACGTGAACAAATCCTACGGCGACAAGGTCGTGGTGCGCGACTTTACCGGCACCATCATGCGCGGCGACAA
GGTCGGCCTGATCGGCCCCAACGGCGCCGGCAAGACCACGCTGCTGCGCCTGATCCTCGGCGAACTGGCGCCCGACAGCG
GCACCGTGCGCAATGGCAGCAACCTGCAGGTCGCGTACTTCGACCAGATGCGCACGCAGCTCGACCTCGAGAAATCGCTG
GCCGACACCATCAGCCCGGGCAGCGACTGGGTCGAGGTCAACGGCCAGCGCAAGCACGTGATGAGCTATCTCGGCGATTT
CCTGTTCGCGCCCGAGCGCGCGCGCTCGCCGGTCAAGTCGCTGTCCGGCGGCGAGCGCAACCGACTGCTGCTGGCACGCC
TGTTCGCGCGCCCGGCCAATGTGCTGGTGCTGGACGAGCCGACCAACGACCTCGACATCGACACGCTGGAACTGCTCGAA
GAGCTGCTGCAGGACTACAGCGGCACCGTGTTCCTGGTCTCGCACGACCGGGCGTTCCTCGACAACGTGGTGACCTCGAC
GATTGCCGCCGAAGGCGACGGCTTGTGGCGCGAATCGGTCGGCGGCTATTCCGACTGGGTTGCGCAGTCCGAGCGCAGCG
CGGCGCTGCAGGCGGCGCGAAAGACCGAGCAGAAGGCGGCCGAGGCTGCCAAGACCAAGGATTCGCGCGACGCGCGCGGC
GCCAACCGTACCGTCAAGCTGTCATACAAGGAACAGCGTGAACTGGACGGGCTGCCGGAGCGGATCGCTTCGCTGGAAAC
GGAACAGAAGACGATCGCCGCGCAGCTTGAGGACGGTTCGCTCTATGTCAGCGATGCGGCCAAGGCCGCCGAACTGGCGA
CCCGGCACGACGAGATCGAGATGGAACTGCTGGAGGCGCTGGAGCGCTGGGAAGTGCTGGAGGCGAAGACGAAGGGCGAG
GCGGGCTAA

Upstream 100 bases:

>100_bases
CTACAATGCGGCCTGCTTCGCCTTGTCGCCGCCGTGCACGCAGGCGCCGGCGACCCATTCCGATTCCGCAATTCCGCAAT
TCCGCTGCCCCATTCCTCCC

Downstream 100 bases:

>100_bases
CCACACCACGCCAGCACCATATTCGTCAGGTCCACCATAAACGACGGCCGCAGATACCCGATAAACCCAAGCACCAGCGC
TGCCGCCAGCCCAAGCAGGC

Product: ABC transporter related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MALFSINDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGSGKSSLLKIVAGLAAPDDGLIARQSGVTSAYVPQEPQFDPG
ITVFDAVSQGMGQAHDLLMRYEAAAERLADSHDEAALAELHRLQSELDAAGAWHLRTRVETTLARLGLDPHTPVDALSGG
LQKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLLSFPGNFAA
YQARKEELLAAEQVEQAKFDKLLAQEEVWIRKGVEARRTRSVARIQRLVAMRSERAARREAQGNVKLEVSQADRSGKIVA
ELIDVNKSYGDKVVVRDFTGTIMRGDKVGLIGPNGAGKTTLLRLILGELAPDSGTVRNGSNLQVAYFDQMRTQLDLEKSL
ADTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGLWRESVGGYSDWVAQSERSAALQAARKTEQKAAEAAKTKDSRDARG
ANRTVKLSYKEQRELDGLPERIASLETEQKTIAAQLEDGSLYVSDAAKAAELATRHDEIEMELLEALERWEVLEAKTKGE
AG

Sequences:

>Translated_642_residues
MALFSINDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGSGKSSLLKIVAGLAAPDDGLIARQSGVTSAYVPQEPQFDPG
ITVFDAVSQGMGQAHDLLMRYEAAAERLADSHDEAALAELHRLQSELDAAGAWHLRTRVETTLARLGLDPHTPVDALSGG
LQKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLLSFPGNFAA
YQARKEELLAAEQVEQAKFDKLLAQEEVWIRKGVEARRTRSVARIQRLVAMRSERAARREAQGNVKLEVSQADRSGKIVA
ELIDVNKSYGDKVVVRDFTGTIMRGDKVGLIGPNGAGKTTLLRLILGELAPDSGTVRNGSNLQVAYFDQMRTQLDLEKSL
ADTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGLWRESVGGYSDWVAQSERSAALQAARKTEQKAAEAAKTKDSRDARG
ANRTVKLSYKEQRELDGLPERIASLETEQKTIAAQLEDGSLYVSDAAKAAELATRHDEIEMELLEALERWEVLEAKTKGE
AG
>Mature_641_residues
ALFSINDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGSGKSSLLKIVAGLAAPDDGLIARQSGVTSAYVPQEPQFDPGI
TVFDAVSQGMGQAHDLLMRYEAAAERLADSHDEAALAELHRLQSELDAAGAWHLRTRVETTLARLGLDPHTPVDALSGGL
QKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLLSFPGNFAAY
QARKEELLAAEQVEQAKFDKLLAQEEVWIRKGVEARRTRSVARIQRLVAMRSERAARREAQGNVKLEVSQADRSGKIVAE
LIDVNKSYGDKVVVRDFTGTIMRGDKVGLIGPNGAGKTTLLRLILGELAPDSGTVRNGSNLQVAYFDQMRTQLDLEKSLA
DTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLEE
LLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGLWRESVGGYSDWVAQSERSAALQAARKTEQKAAEAAKTKDSRDARGA
NRTVKLSYKEQRELDGLPERIASLETEQKTIAAQLEDGSLYVSDAAKAAELATRHDEIEMELLEALERWEVLEAKTKGEA
G

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=538, Percent_Identity=33.6431226765799, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI10947135, Length=499, Percent_Identity=31.4629258517034, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI69354671, Length=499, Percent_Identity=31.4629258517034, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI27881506, Length=538, Percent_Identity=30.2973977695167, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI10947137, Length=538, Percent_Identity=30.2973977695167, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI105990541, Length=226, Percent_Identity=26.1061946902655, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI9955963, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787182, Length=640, Percent_Identity=46.875, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI2367384, Length=538, Percent_Identity=36.8029739776952, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1789751, Length=664, Percent_Identity=30.5722891566265, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787041, Length=534, Percent_Identity=31.6479400749064, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1788506, Length=563, Percent_Identity=24.5115452930728, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48995001, Length=521, Percent_Identity=24.5681381957774, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788165, Length=189, Percent_Identity=34.3915343915344, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693107, Length=564, Percent_Identity=23.0496453900709, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789672, Length=245, Percent_Identity=25.7142857142857, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788761, Length=239, Percent_Identity=30.1255230125523, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=32.6633165829146, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994883, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786872, Length=244, Percent_Identity=29.0983606557377, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081782, Length=272, Percent_Identity=28.3088235294118, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787758, Length=239, Percent_Identity=28.8702928870293, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790190, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=181, Percent_Identity=30.3867403314917, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788897, Length=247, Percent_Identity=27.9352226720648, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=532, Percent_Identity=28.3834586466165, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17553372, Length=546, Percent_Identity=31.8681318681319, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=28.4332688588008, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320874, Length=546, Percent_Identity=28.9377289377289, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6321121, Length=558, Percent_Identity=29.2114695340502, Blast_Score=190, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6325030, Length=394, Percent_Identity=30.4568527918782, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324314, Length=416, Percent_Identity=25.4807692307692, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=269, Percent_Identity=28.2527881040892, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24642252, Length=548, Percent_Identity=30.8394160583942, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI18859989, Length=548, Percent_Identity=30.8394160583942, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24666836, Length=538, Percent_Identity=31.0408921933086, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=29.3893129770992, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI221500365, Length=203, Percent_Identity=32.512315270936, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007184, Length=203, Percent_Identity=32.512315270936, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70331; Mature: 70200

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFSINDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGSGKSSLLKIVAGLAAPDDGLI
CEEEECCCCHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCE
ARQSGVTSAYVPQEPQFDPGITVFDAVSQGMGQAHDLLMRYEAAAERLADSHDEAALAEL
EECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HRLQSELDAAGAWHLRTRVETTLARLGLDPHTPVDALSGGLQKRVALAQGLVAEPDILLL
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEE
DEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLLSFPGNFAA
ECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCHHH
YQARKEELLAAEQVEQAKFDKLLAQEEVWIRKGVEARRTRSVARIQRLVAMRSERAARRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGNVKLEVSQADRSGKIVAELIDVNKSYGDKVVVRDFTGTIMRGDKVGLIGPNGAGKTT
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCEEECCEEEEECCCCCCHHH
LLRLILGELAPDSGTVRNGSNLQVAYFDQMRTQLDLEKSLADTISPGSDWVEVNGQRKHV
HHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
HHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGLWRESVGGYSDWVAQSERSAALQAAR
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
KTEQKAAEAAKTKDSRDARGANRTVKLSYKEQRELDGLPERIASLETEQKTIAAQLEDGS
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHEEECCCC
LYVSDAAKAAELATRHDEIEMELLEALERWEVLEAKTKGEAG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALFSINDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGSGKSSLLKIVAGLAAPDDGLI
EEEECCCCHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCE
ARQSGVTSAYVPQEPQFDPGITVFDAVSQGMGQAHDLLMRYEAAAERLADSHDEAALAEL
EECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HRLQSELDAAGAWHLRTRVETTLARLGLDPHTPVDALSGGLQKRVALAQGLVAEPDILLL
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEE
DEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLLSFPGNFAA
ECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCHHH
YQARKEELLAAEQVEQAKFDKLLAQEEVWIRKGVEARRTRSVARIQRLVAMRSERAARRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGNVKLEVSQADRSGKIVAELIDVNKSYGDKVVVRDFTGTIMRGDKVGLIGPNGAGKTT
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCEEECCEEEEECCCCCCHHH
LLRLILGELAPDSGTVRNGSNLQVAYFDQMRTQLDLEKSLADTISPGSDWVEVNGQRKHV
HHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
HHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGLWRESVGGYSDWVAQSERSAALQAAR
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
KTEQKAAEAAKTKDSRDARGANRTVKLSYKEQRELDGLPERIASLETEQKTIAAQLEDGS
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHEEECCCC
LYVSDAAKAAELATRHDEIEMELLEALERWEVLEAKTKGEAG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]