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The map label for this gene is nagZ [H]

Identifier: 73541934

GI number: 73541934

Start: 2480602

End: 2481651

Strand: Reverse

Name: nagZ [H]

Synonym: Reut_A2247

Alternate gene names: 73541934

Gene position: 2481651-2480602 (Counterclockwise)

Preceding gene: 73541935

Following gene: 73541931

Centisome position: 65.19

GC content: 65.05

Gene sequence:

>1050_bases
ATGATCAAGAAGCTTTCCGGCAAACGGCCGGGACCGGTGGTACTTGACGTCGTCGGCAAGCAGCTCGACGCCGAAGACGG
ACGCCGTATTGCGCACCCGCTGACTGGCGGCGTCATCCTGTTCGCGCGCAACTTCGAGTCGCGCGCGCAATTGCTGGCGC
TCACGCGTGCGATCCGCGCGGTGCGTGAAGACGTGCTGATCTGTATCGACCACGAAGGCGGCCGCGTGCAGCGCTGCAAG
ACCGATGGCTTTACGCATCTGCCAGCGATGCGCAAGCTCGGCGAACTGTGGGAACACGACGTGCTGGCTGCTACCAAGGC
AGCGATCGCGTGCGGCTATGTGCTGGCCGCCGAACTGCGCGCGTGCGATATCGACCTGAGCTTCACGCCGGTGCTCGACC
TCGACTATGGCCGCAGCGCCGTGATCGGCGACCGCGCTTTCCACGCCGATCCGCGCGTGGTCACCATGCTGGCGGGCCAC
CTGAACCATGGCCTGTTGCTGGCCGGCATGAGCAACTGCGGCAAGCACTTCCCCGGCCACGGCTATGTGGAAGCGGACTC
GCATGTCGCGATTCCCGTGGACGAGCGTTCGCTGGAAGATATCCTGTCGCAGGACGCACGTCCGTACGACTGGATGGGCC
TGTCGTTGGCGTCGGTCATGCCGGCGCACGTGATCTACCCGAAGGTCGACCCCAACCCGGCGGGTTTCTCGCGCTTCTGG
CTGCAGGACATCCTGCGTACGCAACTCGGCTTCGAGGGTGTGATCTTCAGCGACGACCTGAGCATGGAAGGCGCCAGCGT
TGCAGGTAACGTCACGCAAGCCGCGCGCGCCGCGCTGGCGGCCGGTTGCGACATGGTGCTGATCTGCAACCATCCCGAGC
GTGCCGACCAGTTGCTGACCGAACTCGACGTGAACATCGGCAAGACTTCGCAGCGCCGGATCCGCAAGCTCTTCGCGCGC
CGCAAGCCGCTCGACTGGAACAAGCTGCAGCAGGAGGGCGAATACCGTGCCGCGCTGCGCCTGCTCAAGGACCACGATCT
GATCGCCTGA

Upstream 100 bases:

>100_bases
TGTCAGTGATGAACGTGACTATGCGGTTGCCTTTGCAATCGCCGAGCGGGGCGGCCATGCGGCAGTCCCCGAAAACCCAG
CCTAGCCTCGAACAAACTCC

Downstream 100 bases:

>100_bases
GCGCGCGACGGGTTTGCGCCAGACGACAAAAAAGGCAGCCGCGGCTGCCTTTTTTCATCACCGGCTCCGCCACGGAGGCG
GAGCGAGCCGTGCGCTTAGT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MIKKLSGKRPGPVVLDVVGKQLDAEDGRRIAHPLTGGVILFARNFESRAQLLALTRAIRAVREDVLICIDHEGGRVQRCK
TDGFTHLPAMRKLGELWEHDVLAATKAAIACGYVLAAELRACDIDLSFTPVLDLDYGRSAVIGDRAFHADPRVVTMLAGH
LNHGLLLAGMSNCGKHFPGHGYVEADSHVAIPVDERSLEDILSQDARPYDWMGLSLASVMPAHVIYPKVDPNPAGFSRFW
LQDILRTQLGFEGVIFSDDLSMEGASVAGNVTQAARAALAAGCDMVLICNHPERADQLLTELDVNIGKTSQRRIRKLFAR
RKPLDWNKLQQEGEYRAALRLLKDHDLIA

Sequences:

>Translated_349_residues
MIKKLSGKRPGPVVLDVVGKQLDAEDGRRIAHPLTGGVILFARNFESRAQLLALTRAIRAVREDVLICIDHEGGRVQRCK
TDGFTHLPAMRKLGELWEHDVLAATKAAIACGYVLAAELRACDIDLSFTPVLDLDYGRSAVIGDRAFHADPRVVTMLAGH
LNHGLLLAGMSNCGKHFPGHGYVEADSHVAIPVDERSLEDILSQDARPYDWMGLSLASVMPAHVIYPKVDPNPAGFSRFW
LQDILRTQLGFEGVIFSDDLSMEGASVAGNVTQAARAALAAGCDMVLICNHPERADQLLTELDVNIGKTSQRRIRKLFAR
RKPLDWNKLQQEGEYRAALRLLKDHDLIA
>Mature_349_residues
MIKKLSGKRPGPVVLDVVGKQLDAEDGRRIAHPLTGGVILFARNFESRAQLLALTRAIRAVREDVLICIDHEGGRVQRCK
TDGFTHLPAMRKLGELWEHDVLAATKAAIACGYVLAAELRACDIDLSFTPVLDLDYGRSAVIGDRAFHADPRVVTMLAGH
LNHGLLLAGMSNCGKHFPGHGYVEADSHVAIPVDERSLEDILSQDARPYDWMGLSLASVMPAHVIYPKVDPNPAGFSRFW
LQDILRTQLGFEGVIFSDDLSMEGASVAGNVTQAARAALAAGCDMVLICNHPERADQLLTELDVNIGKTSQRRIRKLFAR
RKPLDWNKLQQEGEYRAALRLLKDHDLIA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=323, Percent_Identity=45.2012383900929, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 38391; Mature: 38391

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLSGKRPGPVVLDVVGKQLDAEDGRRIAHPLTGGVILFARNFESRAQLLALTRAIRA
CCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHH
VREDVLICIDHEGGRVQRCKTDGFTHLPAMRKLGELWEHDVLAATKAAIACGYVLAAELR
HHCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGRSAVIGDRAFHADPRVVTMLAGHLNHGLLLAGMSNCGKHFPGH
HEECCCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHCCCCCCC
GYVEADSHVAIPVDERSLEDILSQDARPYDWMGLSLASVMPAHVIYPKVDPNPAGFSRFW
CEEECCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCCHHHHH
LQDILRTQLGFEGVIFSDDLSMEGASVAGNVTQAARAALAAGCDMVLICNHPERADQLLT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ELDVNIGKTSQRRIRKLFARRKPLDWNKLQQEGEYRAALRLLKDHDLIA
HHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKKLSGKRPGPVVLDVVGKQLDAEDGRRIAHPLTGGVILFARNFESRAQLLALTRAIRA
CCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHH
VREDVLICIDHEGGRVQRCKTDGFTHLPAMRKLGELWEHDVLAATKAAIACGYVLAAELR
HHCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGRSAVIGDRAFHADPRVVTMLAGHLNHGLLLAGMSNCGKHFPGH
HEECCCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHCCCCCCC
GYVEADSHVAIPVDERSLEDILSQDARPYDWMGLSLASVMPAHVIYPKVDPNPAGFSRFW
CEEECCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCCHHHHH
LQDILRTQLGFEGVIFSDDLSMEGASVAGNVTQAARAALAAGCDMVLICNHPERADQLLT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ELDVNIGKTSQRRIRKLFARRKPLDWNKLQQEGEYRAALRLLKDHDLIA
HHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA