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The map label for this gene is acpS

Identifier: 73541935

GI number: 73541935

Start: 2481667

End: 2482089

Strand: Reverse

Name: acpS

Synonym: Reut_A2248

Alternate gene names: 73541935

Gene position: 2482089-2481667 (Counterclockwise)

Preceding gene: 73541936

Following gene: 73541934

Centisome position: 65.21

GC content: 66.67

Gene sequence:

>423_bases
GTGATCTACGGCGTCGGCACCGACATCATCGAGATCGCGCGCGTGCAGGGCGTGATGGAGCGCACGCGCGGCCGCTTTGC
CGAGAAGGTGCTCGGGGCCGATGAACTGGCCAAGTACCACGCGCGCAAGGCGCGCTCCGAGCGGCGCGGGCTGGCCTTCC
TGGCGACGCGCTTTGCCGCCAAGGAGGCCTTCTCCAAGGCCATCGGCCTCGGCATGCGCTGGCCGATGACCTGGCGCGCG
ATGGAACTGATGAACCTGCCTTCTGGCGAGCCGACGCCGATCTGTCATGGTGAACTCGCGCAGTGGATCGCGGAACGCGG
CATCACCGTGCGTGTCAGTGTCAGTGATGAACGTGACTATGCGGTTGCCTTTGCAATCGCCGAGCGGGGCGGCCATGCGG
CAGTCCCCGAAAACCCAGCCTAG

Upstream 100 bases:

>100_bases
ATGCCGTGTTCGTGGGCTGGCAAAACGCCGTGCGCGAGATGAAGGCCATCATGGTGGCCGCGCGCCTCGGCACCCGTTAC
CCCGCTGCAGGCAAGCCGGC

Downstream 100 bases:

>100_bases
CCTCGAACAAACTCCATGATCAAGAAGCTTTCCGGCAAACGGCCGGGACCGGTGGTACTTGACGTCGTCGGCAAGCAGCT
CGACGCCGAAGACGGACGCC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MIYGVGTDIIEIARVQGVMERTRGRFAEKVLGADELAKYHARKARSERRGLAFLATRFAAKEAFSKAIGLGMRWPMTWRA
MELMNLPSGEPTPICHGELAQWIAERGITVRVSVSDERDYAVAFAIAERGGHAAVPENPA

Sequences:

>Translated_140_residues
MIYGVGTDIIEIARVQGVMERTRGRFAEKVLGADELAKYHARKARSERRGLAFLATRFAAKEAFSKAIGLGMRWPMTWRA
MELMNLPSGEPTPICHGELAQWIAERGITVRVSVSDERDYAVAFAIAERGGHAAVPENPA
>Mature_140_residues
MIYGVGTDIIEIARVQGVMERTRGRFAEKVLGADELAKYHARKARSERRGLAFLATRFAAKEAFSKAIGLGMRWPMTWRA
MELMNLPSGEPTPICHGELAQWIAERGITVRVSVSDERDYAVAFAIAERGGHAAVPENPA

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=37.5, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CUPPJ (Q46Z22)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_296455.1
- ProteinModelPortal:   Q46Z22
- SMR:   Q46Z22
- GeneID:   3610591
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2248
- NMPDR:   fig|264198.3.peg.2851
- HOGENOM:   HBG734479
- OMA:   DYAIAFI
- ProtClustDB:   PRK00070
- BioCyc:   REUT264198:REUT_A2248-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15457; Mature: 15457

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGVGTDIIEIARVQGVMERTRGRFAEKVLGADELAKYHARKARSERRGLAFLATRFAA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KEAFSKAIGLGMRWPMTWRAMELMNLPSGEPTPICHGELAQWIAERGITVRVSVSDERDY
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCE
AVAFAIAERGGHAAVPENPA
EEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIYGVGTDIIEIARVQGVMERTRGRFAEKVLGADELAKYHARKARSERRGLAFLATRFAA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KEAFSKAIGLGMRWPMTWRAMELMNLPSGEPTPICHGELAQWIAERGITVRVSVSDERDY
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCE
AVAFAIAERGGHAAVPENPA
EEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA