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The map label for this gene is exbB [H]

Identifier: 73541923

GI number: 73541923

Start: 2469410

End: 2470138

Strand: Direct

Name: exbB [H]

Synonym: Reut_A2236

Alternate gene names: 73541923

Gene position: 2469410-2470138 (Clockwise)

Preceding gene: 73541922

Following gene: 73541924

Centisome position: 64.87

GC content: 63.92

Gene sequence:

>729_bases
ATGCAGGATCTCGGACTTTCCCACCTCTGGTCGCAAGGCGATTTCGTCATGCGTGCGACGGCCATCATTCTGCTGATCAT
GTCGCTCTTGTCGTGGATCGTGATCCTCACCAAGGCGTGGGATCTGATTCGGCTGAAGAAGATGGCGCACGGCGCGGAAA
AGCGCTTCTGGCACTCCGACGACTTCGACCACGCGCTGGAGACACTCGGTTCCAATGACGCGAACCCGTTCCGCACGCTG
GCCATCGCCGGCAAGGAAGCGGCACAGCACCACCGCGCCAGCCAGCCGCAACTGCATGACGTGATGGACATCTCCGACTG
GCTGACGCGCTCGCTCAAGAGTTCGATCGACGACGCCGTGGCACACATGCAGTCTGGCCTGGCCGTGCTGGCTTCGGTTG
GCTCGACCGCGCCGTTCGTGGGCCTGTTCGGCACGGTGTGGGGCATCTACCATGCACTGATCGGTATCGGTGCCTCAGGC
GTGCCGACGATCGACAAGGTCGCCGGCCCGGTCGGTGAAGCGCTGATCATGACCGCTTTCGGCCTGGCCGTTGCGATTCC
GGCCGTGCTGGGCTACAACGCACTGACCCGTGGCAACAAGTCGGTCATCTCCAAGCTGAACCGCTTCGCGCACGACCTGC
ACGCCTATTTCGTGACCGGCGCACGCGTTCGGCCGGCCAGCACCCGCGGCGACGACAACGCCGTACGCCTCGCCTCTGCA
CGGCAGTAA

Upstream 100 bases:

>100_bases
GTACATGGACAACGGCCGCGCCATCGCCGTGACCGCGCAGCAGCCGATCGGATTCGAACTCAACTGATCTCAACCTACAA
CGCACCTACCAGGAACCAAC

Downstream 100 bases:

>100_bases
CACTACCGCATCAAGGAAGTCATCATGGCATTTGGCACGCTCGACGGGGACGATGACGAGGTGATGAGCGAAATCAACAT
GACGCCGCTGGTCGACGTCA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQDLGLSHLWSQGDFVMRATAIILLIMSLLSWIVILTKAWDLIRLKKMAHGAEKRFWHSDDFDHALETLGSNDANPFRTL
AIAGKEAAQHHRASQPQLHDVMDISDWLTRSLKSSIDDAVAHMQSGLAVLASVGSTAPFVGLFGTVWGIYHALIGIGASG
VPTIDKVAGPVGEALIMTAFGLAVAIPAVLGYNALTRGNKSVISKLNRFAHDLHAYFVTGARVRPASTRGDDNAVRLASA
RQ

Sequences:

>Translated_242_residues
MQDLGLSHLWSQGDFVMRATAIILLIMSLLSWIVILTKAWDLIRLKKMAHGAEKRFWHSDDFDHALETLGSNDANPFRTL
AIAGKEAAQHHRASQPQLHDVMDISDWLTRSLKSSIDDAVAHMQSGLAVLASVGSTAPFVGLFGTVWGIYHALIGIGASG
VPTIDKVAGPVGEALIMTAFGLAVAIPAVLGYNALTRGNKSVISKLNRFAHDLHAYFVTGARVRPASTRGDDNAVRLASA
RQ
>Mature_242_residues
MQDLGLSHLWSQGDFVMRATAIILLIMSLLSWIVILTKAWDLIRLKKMAHGAEKRFWHSDDFDHALETLGSNDANPFRTL
AIAGKEAAQHHRASQPQLHDVMDISDWLTRSLKSSIDDAVAHMQSGLAVLASVGSTAPFVGLFGTVWGIYHALIGIGASG
VPTIDKVAGPVGEALIMTAFGLAVAIPAVLGYNALTRGNKSVISKLNRFAHDLHAYFVTGARVRPASTRGDDNAVRLASA
RQ

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=233, Percent_Identity=29.1845493562232, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789381, Length=198, Percent_Identity=29.2929292929293, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26085; Mature: 26085

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLGLSHLWSQGDFVMRATAIILLIMSLLSWIVILTKAWDLIRLKKMAHGAEKRFWHSD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDHALETLGSNDANPFRTLAIAGKEAAQHHRASQPQLHDVMDISDWLTRSLKSSIDDAV
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHMQSGLAVLASVGSTAPFVGLFGTVWGIYHALIGIGASGVPTIDKVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHH
GLAVAIPAVLGYNALTRGNKSVISKLNRFAHDLHAYFVTGARVRPASTRGDDNAVRLASA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCC
RQ
CC
>Mature Secondary Structure
MQDLGLSHLWSQGDFVMRATAIILLIMSLLSWIVILTKAWDLIRLKKMAHGAEKRFWHSD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDHALETLGSNDANPFRTLAIAGKEAAQHHRASQPQLHDVMDISDWLTRSLKSSIDDAV
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHMQSGLAVLASVGSTAPFVGLFGTVWGIYHALIGIGASGVPTIDKVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHH
GLAVAIPAVLGYNALTRGNKSVISKLNRFAHDLHAYFVTGARVRPASTRGDDNAVRLASA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCC
RQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]