Click here to switch to the map view.

The map label for this gene is glpD2 [H]

Identifier: 73541901

GI number: 73541901

Start: 2447651

End: 2449255

Strand: Direct

Name: glpD2 [H]

Synonym: Reut_A2214

Alternate gene names: 73541901

Gene position: 2447651-2449255 (Clockwise)

Preceding gene: 73541900

Following gene: 73541902

Centisome position: 64.3

GC content: 68.85

Gene sequence:

>1605_bases
ATGCCGAAAGCCCCGACCCCGATCCAGCCGCCGTCCCGAGCCGCCCTGCTCGCAAGGCTGGAACGCGAGCCGCGCTGGGA
CGTGATCGTCATCGGTGGCGGCGCCACCGGCCTCGGCACGGCCGTCGATGCCGCGTCGCGCGGATATCGCACACTGCTGG
TGGAGGCCGCCGACTTCGCCAAGGGCACGTCGAGCAAGGCCACCAAGCTCGTGCACGGCGGCGTGCGCTACCTGGCCCAG
GGCAATATCAGCCTGGTGCGCGAAGCGCTGCATGAACGCGGGCTGCTCGCCCGCAACGCGCCTCACCTCGTGTGGCCGCT
CGGCTTTGTCGTACCGGCTTACCAGCTGTTCGACCAGCCGTTCTATGGCATCGGCCTGAAGCTTTATGACATGCTGGCCG
GCGGCCTGAATCTCGATGGCAGCCGCTGGCTCAACCACCGCGAGGTACTGGCCGCCGCCCCCACGCTGGCCGAGCATGTC
GGCGGACGCCCGCTGCGCGGCGGCAACCTGTACTTCGACGGCCAGTTCGACGACGCACGCCTCGCCATTGCGCTGATGCG
CACGCTGTTCGACGTCGGCGGCACCGCCATCAACTACCTGCCGGTAATCGGCCTGTCGCAGCAGGGCGGCGTGGTCAATG
GCGTGACCGTGCGAGATGCGCTTGGCGATACCACGTTCCGCCTGCGCGCGGATTGCGTGGTCAATGCCACCGGCGTGTGG
GTGGATGCCATCCGCCGGATGGAAGACGGGCAGGCGCGCACCATGGTCGCGCCGAGCCAGGGTGTGCATCTGACGCTGCC
GCGCAGCTTCCTGCCCGGCGATCGCGCCATCCTGATTCCGAAGACCGATGACGGCCGCGTGTTGTTCGTGGTGCCGTGGA
ACGGGCATGTCATCGTCGGCACCACCGACACGCCGCGCAAGGACCTGCCGCTGGAGCCTGGCGCAAGCGGCGACGATGTG
GATTTCATCCTCGATACCGCTTCGCGTTACCTGGCGCGCGACCCCGGCCGCACCGATGTCACAAGCGTCTGGGCCGGATT
GCGGCCGCTGGTCAAGGCGACAGGCGAGGCATCCACGGCTTCGCTGTCGCGCGAGCACACCATCGTGGTGTCGCGCGCCG
GGCTGATCACGGTGACCGGCGGCAAATGGACCACGTACCGCAAGATGGCCGAAGATGTCATCGAGACGGCCATCCAGCGC
CAGATGCTGCGCGCCGCGCCTTGCGTGACCGCCGATCTGCCGCTGCACGGCGCGAGCGGCCTGCCAGCCGACCTGCCCGC
GCCGAATTCGGTGTCGCCCGATCGCTACTATGGCAATGAGTTGCCCGCATTGCGCGCCTTGCCCGGCATCGACCATGTCC
TGGCGCCGGCGTCCGGGCTGACCGAGGCGCACGTGCGCTTTGCGGCTCGCCATGAACTCGCGCGCCGCGTCGAGGATGTG
CTGGCGCGGCGCAACCGCGCGCTGTTCCTGGACGCGCGCGCGGCCGTGGAAGCCGCCCCACAGGTGGCAGCGATCCTGGC
GGAAGAACTGGGCCACGACGAAGCCTGGCAGGCCAGCGAAGTGGAAAACTTCCGCAAGCTCGCCGCCGGATACATGCTCG
ACTGA

Upstream 100 bases:

>100_bases
CTGGGCCCGGGAAGATCACGAGGCCACCAGCGGCAAGAGAACGTGACGCGCCGTCGCGGCCACACCTTACGGAACCCTTT
ATTCAGATTCAGAGAGTGTC

Downstream 100 bases:

>100_bases
ACGTGACGGATGCCGGATCCACGTATCCGACCGGAAAACTGATATGACCCATCACCCGCACCCGCACCCGCTCGCCCTCC
CCGCCCTGCTTCTGGCCGTT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MPKAPTPIQPPSRAALLARLEREPRWDVIVIGGGATGLGTAVDAASRGYRTLLVEAADFAKGTSSKATKLVHGGVRYLAQ
GNISLVREALHERGLLARNAPHLVWPLGFVVPAYQLFDQPFYGIGLKLYDMLAGGLNLDGSRWLNHREVLAAAPTLAEHV
GGRPLRGGNLYFDGQFDDARLAIALMRTLFDVGGTAINYLPVIGLSQQGGVVNGVTVRDALGDTTFRLRADCVVNATGVW
VDAIRRMEDGQARTMVAPSQGVHLTLPRSFLPGDRAILIPKTDDGRVLFVVPWNGHVIVGTTDTPRKDLPLEPGASGDDV
DFILDTASRYLARDPGRTDVTSVWAGLRPLVKATGEASTASLSREHTIVVSRAGLITVTGGKWTTYRKMAEDVIETAIQR
QMLRAAPCVTADLPLHGASGLPADLPAPNSVSPDRYYGNELPALRALPGIDHVLAPASGLTEAHVRFAARHELARRVEDV
LARRNRALFLDARAAVEAAPQVAAILAEELGHDEAWQASEVENFRKLAAGYMLD

Sequences:

>Translated_534_residues
MPKAPTPIQPPSRAALLARLEREPRWDVIVIGGGATGLGTAVDAASRGYRTLLVEAADFAKGTSSKATKLVHGGVRYLAQ
GNISLVREALHERGLLARNAPHLVWPLGFVVPAYQLFDQPFYGIGLKLYDMLAGGLNLDGSRWLNHREVLAAAPTLAEHV
GGRPLRGGNLYFDGQFDDARLAIALMRTLFDVGGTAINYLPVIGLSQQGGVVNGVTVRDALGDTTFRLRADCVVNATGVW
VDAIRRMEDGQARTMVAPSQGVHLTLPRSFLPGDRAILIPKTDDGRVLFVVPWNGHVIVGTTDTPRKDLPLEPGASGDDV
DFILDTASRYLARDPGRTDVTSVWAGLRPLVKATGEASTASLSREHTIVVSRAGLITVTGGKWTTYRKMAEDVIETAIQR
QMLRAAPCVTADLPLHGASGLPADLPAPNSVSPDRYYGNELPALRALPGIDHVLAPASGLTEAHVRFAARHELARRVEDV
LARRNRALFLDARAAVEAAPQVAAILAEELGHDEAWQASEVENFRKLAAGYMLD
>Mature_533_residues
PKAPTPIQPPSRAALLARLEREPRWDVIVIGGGATGLGTAVDAASRGYRTLLVEAADFAKGTSSKATKLVHGGVRYLAQG
NISLVREALHERGLLARNAPHLVWPLGFVVPAYQLFDQPFYGIGLKLYDMLAGGLNLDGSRWLNHREVLAAAPTLAEHVG
GRPLRGGNLYFDGQFDDARLAIALMRTLFDVGGTAINYLPVIGLSQQGGVVNGVTVRDALGDTTFRLRADCVVNATGVWV
DAIRRMEDGQARTMVAPSQGVHLTLPRSFLPGDRAILIPKTDDGRVLFVVPWNGHVIVGTTDTPRKDLPLEPGASGDDVD
FILDTASRYLARDPGRTDVTSVWAGLRPLVKATGEASTASLSREHTIVVSRAGLITVTGGKWTTYRKMAEDVIETAIQRQ
MLRAAPCVTADLPLHGASGLPADLPAPNSVSPDRYYGNELPALRALPGIDHVLAPASGLTEAHVRFAARHELARRVEDVL
ARRNRALFLDARAAVEAAPQVAAILAEELGHDEAWQASEVENFRKLAAGYMLD

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=556, Percent_Identity=38.8489208633094, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI285002231, Length=556, Percent_Identity=38.8489208633094, Blast_Score=368, Evalue=1e-102,
Organism=Escherichia coli, GI2367226, Length=469, Percent_Identity=29.8507462686567, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788574, Length=420, Percent_Identity=30, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509253, Length=559, Percent_Identity=38.819320214669, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI115534726, Length=551, Percent_Identity=36.4791288566243, Blast_Score=323, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322036, Length=611, Percent_Identity=35.3518821603928, Blast_Score=293, Evalue=4e-80,
Organism=Drosophila melanogaster, GI161077125, Length=556, Percent_Identity=37.589928057554, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24653942, Length=556, Percent_Identity=37.589928057554, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24653944, Length=556, Percent_Identity=37.589928057554, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI20130025, Length=556, Percent_Identity=37.589928057554, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI19921278, Length=545, Percent_Identity=33.0275229357798, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24586295, Length=544, Percent_Identity=31.4338235294118, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI45550977, Length=384, Percent_Identity=32.03125, Blast_Score=178, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57371; Mature: 57240

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAPTPIQPPSRAALLARLEREPRWDVIVIGGGATGLGTAVDAASRGYRTLLVEAADFA
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEEHHHHC
KGTSSKATKLVHGGVRYLAQGNISLVREALHERGLLARNAPHLVWPLGFVVPAYQLFDQP
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCC
FYGIGLKLYDMLAGGLNLDGSRWLNHREVLAAAPTLAEHVGGRPLRGGNLYFDGQFDDAR
CHHCCHHHHHHHHCCCCCCHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCHH
LAIALMRTLFDVGGTAINYLPVIGLSQQGGVVNGVTVRDALGDTTFRLRADCVVNATGVW
HHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEECEEEHHHCCCCEEEEEEEEEEECCHHH
VDAIRRMEDGQARTMVAPSQGVHLTLPRSFLPGDRAILIPKTDDGRVLFVVPWNGHVIVG
HHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCEEEEE
TTDTPRKDLPLEPGASGDDVDFILDTASRYLARDPGRTDVTSVWAGLRPLVKATGEASTA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHH
SLSREHTIVVSRAGLITVTGGKWTTYRKMAEDVIETAIQRQMLRAAPCVTADLPLHGASG
HCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
LPADLPAPNSVSPDRYYGNELPALRALPGIDHVLAPASGLTEAHVRFAARHELARRVEDV
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LARRNRALFLDARAAVEAAPQVAAILAEELGHDEAWQASEVENFRKLAAGYMLD
HHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKAPTPIQPPSRAALLARLEREPRWDVIVIGGGATGLGTAVDAASRGYRTLLVEAADFA
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCEEEEEEHHHHC
KGTSSKATKLVHGGVRYLAQGNISLVREALHERGLLARNAPHLVWPLGFVVPAYQLFDQP
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCC
FYGIGLKLYDMLAGGLNLDGSRWLNHREVLAAAPTLAEHVGGRPLRGGNLYFDGQFDDAR
CHHCCHHHHHHHHCCCCCCHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCHH
LAIALMRTLFDVGGTAINYLPVIGLSQQGGVVNGVTVRDALGDTTFRLRADCVVNATGVW
HHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEECEEEHHHCCCCEEEEEEEEEEECCHHH
VDAIRRMEDGQARTMVAPSQGVHLTLPRSFLPGDRAILIPKTDDGRVLFVVPWNGHVIVG
HHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCEEEEE
TTDTPRKDLPLEPGASGDDVDFILDTASRYLARDPGRTDVTSVWAGLRPLVKATGEASTA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHH
SLSREHTIVVSRAGLITVTGGKWTTYRKMAEDVIETAIQRQMLRAAPCVTADLPLHGASG
HCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
LPADLPAPNSVSPDRYYGNELPALRALPGIDHVLAPASGLTEAHVRFAARHELARRVEDV
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LARRNRALFLDARAAVEAAPQVAAILAEELGHDEAWQASEVENFRKLAAGYMLD
HHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]