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The map label for this gene is hflC [H]

Identifier: 73541766

GI number: 73541766

Start: 2284517

End: 2285428

Strand: Reverse

Name: hflC [H]

Synonym: Reut_A2078

Alternate gene names: 73541766

Gene position: 2285428-2284517 (Counterclockwise)

Preceding gene: 73541767

Following gene: 73541765

Centisome position: 60.04

GC content: 63.82

Gene sequence:

>912_bases
ATGAACCGACTGATTTCCTTTGCGATCGGCGCTTTCATCGTGCTCGCCGTGGCGTCTTCGATGATGTTCGTCGTGGATCA
GCGCCAGTACGCCGTGGTGTTCGCCTTCGGCGAGATCAAGCAGGTGGTGCGCGAGCCGGGCCTGCACTTCAAGTTGCCGC
CGCCGCTGCAGAACGTGGTGTTCATGGACCGCCGCCTGCAGACCATCGACGTGGCCGCCAGCGAGCGCTTCCTGACCGCT
GAAAAGAAGAGCATGGTGGTGGACTGGTTCGTCAAATGGCGCATCACTGATCCGCGCAAGTTCTACGTCGCGTTCGGCGG
CAATGTGCGCAGCGCTCAGGACCGCATGACGCAGCGTATTGATGCCGTCGCGCGCGAAGAGTTCGGCAAGCGCACCGTGG
CTGACGTGGTCGCCGGCGAGCGCGAGAAGGTTATGCAGAATATCCGCGCCGGCATGTCGGAGTATGCGCAGTCGGTCGGG
GTCGAGATCCTGGACGTGCGCCTCAAGCGCGTGGACCTGCTGCCGGCCATCAGTGAATCGGTGTACCGCCGCATGGAAGC
CGAGCGCAAGCGCGTGGCTAACGAATTGCGCTCGACGGGTGCCGCGGAAGGCGAAAAGATCCGCGCCGATGCGGACCGCC
AGCGCGAAGTGGTGCTGGCCGAAGCCTATCGCGACGCCCAGGTAATCAAGGGAGAGGGCGATGCGAAGTCTTCGCAGATC
TATGCCGATGCCTTCGGCAAGGATCCCCAGTTCGCGCAGTTCTGGCGCAGCATGGAGGCATATCGCAATACCTTCCGCGA
CAAGCGCGACATCATGGTGCTGGAGCCGAACTCGGACTTCTTCCGCTACATGCGATCAAGCGGTGGCGCTGCGGCGCCGG
CGGCAAGCGGCGCGTCCGGAGGGCGGCGCTAG

Upstream 100 bases:

>100_bases
GGTGCCGGCACGCCAGCGCCCACGCAGGATTCCCCCGGCGACAACCGGTCGCGCGAATCCCTGCGCAACCGTGACCGCGA
TTCGCGCTGAGGAGACCGTC

Downstream 100 bases:

>100_bases
CGAGACCGCGGAATTTGTGGCGAGATGACAAAACCCCGGCTTGCCGGGGTTTTGTCCGGCTGGAGGTCTGCACCGGAAGT
GACGGCGCGGACGCGCTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNRLISFAIGAFIVLAVASSMMFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAASERFLTA
EKKSMVVDWFVKWRITDPRKFYVAFGGNVRSAQDRMTQRIDAVAREEFGKRTVADVVAGEREKVMQNIRAGMSEYAQSVG
VEILDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVIKGEGDAKSSQI
YADAFGKDPQFAQFWRSMEAYRNTFRDKRDIMVLEPNSDFFRYMRSSGGAAAPAASGASGGRR

Sequences:

>Translated_303_residues
MNRLISFAIGAFIVLAVASSMMFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAASERFLTA
EKKSMVVDWFVKWRITDPRKFYVAFGGNVRSAQDRMTQRIDAVAREEFGKRTVADVVAGEREKVMQNIRAGMSEYAQSVG
VEILDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVIKGEGDAKSSQI
YADAFGKDPQFAQFWRSMEAYRNTFRDKRDIMVLEPNSDFFRYMRSSGGAAAPAASGASGGRR
>Mature_303_residues
MNRLISFAIGAFIVLAVASSMMFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAASERFLTA
EKKSMVVDWFVKWRITDPRKFYVAFGGNVRSAQDRMTQRIDAVAREEFGKRTVADVVAGEREKVMQNIRAGMSEYAQSVG
VEILDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVIKGEGDAKSSQI
YADAFGKDPQFAQFWRSMEAYRNTFRDKRDIMVLEPNSDFFRYMRSSGGAAAPAASGASGGRR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=36.0759493670886, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34230; Mature: 34230

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLISFAIGAFIVLAVASSMMFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVV
CCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDRRLQTIDVAASERFLTAEKKSMVVDWFVKWRITDPRKFYVAFGGNVRSAQDRMTQRI
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
DAVAREEFGKRTVADVVAGEREKVMQNIRAGMSEYAQSVGVEILDVRLKRVDLLPAISES
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVIKGEGDAKSSQI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEE
YADAFGKDPQFAQFWRSMEAYRNTFRDKRDIMVLEPNSDFFRYMRSSGGAAAPAASGASG
EHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
GRR
CCC
>Mature Secondary Structure
MNRLISFAIGAFIVLAVASSMMFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVV
CCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDRRLQTIDVAASERFLTAEKKSMVVDWFVKWRITDPRKFYVAFGGNVRSAQDRMTQRI
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
DAVAREEFGKRTVADVVAGEREKVMQNIRAGMSEYAQSVGVEILDVRLKRVDLLPAISES
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVIKGEGDAKSSQI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEE
YADAFGKDPQFAQFWRSMEAYRNTFRDKRDIMVLEPNSDFFRYMRSSGGAAAPAASGASG
EHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
GRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]