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The map label for this gene is btr [H]

Identifier: 73541722

GI number: 73541722

Start: 2234044

End: 2234742

Strand: Direct

Name: btr [H]

Synonym: Reut_A2034

Alternate gene names: 73541722

Gene position: 2234044-2234742 (Clockwise)

Preceding gene: 73541713

Following gene: 73541741

Centisome position: 58.69

GC content: 60.8

Gene sequence:

>699_bases
ATGTCGCCCCGTTGCTCCACTTGCGGCATGGGGCAACTGTGCCTGCCGGTGGGCATGAACCAGCAAGACCTGCAGAAGAT
GGACACTCTGGTGCAGGAACGCGTTCGCGTCCACAAGGGCGAGACCCTGTACCGCATGGGCGATCCGTTGACCGCGGTCT
ATGCGATCCGCTTCGGCACCTTGAAAACGCATGTGACCACGGAAGACGGCCGCTCGCAAATCACCGGATTCCATCTGCCC
GGCGAGGTGGTCGGCCTCGACGGCCTCGGCGAAATGCAGCACGCGTCGGACGCAACCGCACTCGAAGATACCGAAGTCTG
CGTTGTGCGCCTGTCCGACCTGCAGTCGCTTTCGATGGACCTGCCATCGCTGCAGCAGCAGTTCCTTCGCCTGATGGGCA
AAGAAATCTCGAATGACCAACTCATGCTCGTCACGCTGGGCTCCATGCGCGCCGAAGAACGCCTTGCCGCGTTCCTGATC
AACCTGTCCGAACGACTCTCCGCGCGTGGCTATTCTTCGACCGAGTTCGTCATGCGCATGAGCCGCGAAGAAATCGGCAG
CTATCTCGGGCTGAAACTCGAAACCGTCAGCCGCCTTTTCTCGCGCTTTGCCGAAGCCGGCCTGATCCAGATTCGCCAGC
GCCATGTGAAACTCGTCGACATGGCAGGCATCAAGCAGGTCTACAGCCGTTCCTGCTGA

Upstream 100 bases:

>100_bases
CTCCCTACCGCATCACATCGCGCGTTAAAATGCATACATTGCGCCCTCGCCGCTCATTACTCGCAGGTTCCAATTGCTAA
CATCCATTCCCGTCACCGAG

Downstream 100 bases:

>100_bases
AGCAGACGGCCGCCTTGCGTGGCAAGGCGGCCGTCCTCCCTTTTACTCCAGTTCGTCCGTTTCGCTGAGCTTCGTCGGCA
TCGTGTACAGCGTCAAGCCG

Product: cyclic nucleotide-binding: regulatory protein, Crp

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSPRCSTCGMGQLCLPVGMNQQDLQKMDTLVQERVRVHKGETLYRMGDPLTAVYAIRFGTLKTHVTTEDGRSQITGFHLP
GEVVGLDGLGEMQHASDATALEDTEVCVVRLSDLQSLSMDLPSLQQQFLRLMGKEISNDQLMLVTLGSMRAEERLAAFLI
NLSERLSARGYSSTEFVMRMSREEIGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLVDMAGIKQVYSRSC

Sequences:

>Translated_232_residues
MSPRCSTCGMGQLCLPVGMNQQDLQKMDTLVQERVRVHKGETLYRMGDPLTAVYAIRFGTLKTHVTTEDGRSQITGFHLP
GEVVGLDGLGEMQHASDATALEDTEVCVVRLSDLQSLSMDLPSLQQQFLRLMGKEISNDQLMLVTLGSMRAEERLAAFLI
NLSERLSARGYSSTEFVMRMSREEIGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLVDMAGIKQVYSRSC
>Mature_231_residues
SPRCSTCGMGQLCLPVGMNQQDLQKMDTLVQERVRVHKGETLYRMGDPLTAVYAIRFGTLKTHVTTEDGRSQITGFHLPG
EVVGLDGLGEMQHASDATALEDTEVCVVRLSDLQSLSMDLPSLQQQFLRLMGKEISNDQLMLVTLGSMRAEERLAAFLIN
LSERLSARGYSSTEFVMRMSREEIGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLVDMAGIKQVYSRSC

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=43.0493273542601, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25910; Mature: 25779

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRCSTCGMGQLCLPVGMNQQDLQKMDTLVQERVRVHKGETLYRMGDPLTAVYAIRFGT
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCC
LKTHVTTEDGRSQITGFHLPGEVVGLDGLGEMQHASDATALEDTEVCVVRLSDLQSLSMD
EEEEEECCCCCCCCEEEECCCCEECCCCCCCHHHCCCCCCCCCCCEEEEEHHHHHHHHCC
LPSLQQQFLRLMGKEISNDQLMLVTLGSMRAEERLAAFLINLSERLSARGYSSTEFVMRM
CHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SREEIGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLVDMAGIKQVYSRSC
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPRCSTCGMGQLCLPVGMNQQDLQKMDTLVQERVRVHKGETLYRMGDPLTAVYAIRFGT
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCC
LKTHVTTEDGRSQITGFHLPGEVVGLDGLGEMQHASDATALEDTEVCVVRLSDLQSLSMD
EEEEEECCCCCCCCEEEECCCCEECCCCCCCHHHCCCCCCCCCCCEEEEEHHHHHHHHCC
LPSLQQQFLRLMGKEISNDQLMLVTLGSMRAEERLAAFLINLSERLSARGYSSTEFVMRM
CHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SREEIGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLVDMAGIKQVYSRSC
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]