| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is fabG [H]
Identifier: 73541517
GI number: 73541517
Start: 2003551
End: 2004351
Strand: Direct
Name: fabG [H]
Synonym: Reut_A1828
Alternate gene names: 73541517
Gene position: 2003551-2004351 (Clockwise)
Preceding gene: 73541516
Following gene: 73541527
Centisome position: 52.63
GC content: 70.54
Gene sequence:
>801_bases ATGAAGAATCTTGAAGGCAAGGTGGCGATCGTCACCGGCGGCACCGGCGGGATCGGCCGGGGCGTGGCACTGCAGCTCGC GGCGCGCGGGGCGCTGGTGGTCATCAGCGGCAGGAGCGCGTCAAAGGCGGACGCGGTGCTCGCCGAACTGCGCGAGGCGG GCGGCCAGGGCGATTTCATCCCCGGCGACGTCCGCGTGAAGGCCGACATGGATGCGCTCGCCGCCGAGACCGCGCGCCGC CACGGCGGCATCGATATCGTGGTCGCCAATGCCGGCGGCAACGACGACGAGGCGCGCCGCCCGGAAGTGCGCGGGCCGTT TGGCGATATCGACGTCGCGCGCGTCTGCGCCGTGGTGGCGGAGAACACCGCCGCGAAGCTGCTGCCGGTGCAGTCGGCCC TGCCCTTCCTGCGCGAGCGCGGCGGCGGCGCGGTGGTCTTCGTGACCTCGGAAGGTGGGCGCGTGCCGACGCCGACGCAG ACCGCGGTGGCCACCTTTGCCGGCGGCCTGATCAGCGCAAGCAAGGTGCTATCGAAGGAACTCGCGCGCGACCGCATCCG CGTGAACTGTGTATGCGTGACGGTGGTGCGCGACAGTCCCTCCTGGAAGGCCGCGTTCGAGCGCACCGATGGCGTGTCGG ACCGGCACCGCAAGCAGTACGAGAAAATCATCGCCAGCAGCCCGCTCGGCGTGGCAAGCCCGGAGGATATCGGCCAGGTG GTGGCTTTCCTCGCCTCCGACGAGTCGCGCTACCTGACTGGGGCGACCATCAGCCCGACCGGCGGGCTGACGATTCACTG A
Upstream 100 bases:
>100_bases TGCGCGACTGGCTACACCTCGATGCGCGGCAGGTCGCCGCGCTGCGCGCCGACGGCATCGTCTGACCGGAAGACAGTGAA AGCACAGCAAGGAACCAGCA
Downstream 100 bases:
>100_bases CGATCTGCTGAAGACCGGCTGCGCGGCCCGCCGCCTCACACAATGGCGCCGGCCGCGCGCAATGCCGCAATGTCAGGTGC GCTGAAGCCCCAGTCGCCTA
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 266; Mature: 266
Protein sequence:
>266_residues MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV VAFLASDESRYLTGATISPTGGLTIH
Sequences:
>Translated_266_residues MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV VAFLASDESRYLTGATISPTGGLTIH >Mature_266_residues MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFIPGDVRVKADMDALAAETARR HGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVAENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQ TAVATFAGGLISASKVLSKELARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV VAFLASDESRYLTGATISPTGGLTIH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI126723750, Length=276, Percent_Identity=29.7101449275362, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI19923817, Length=280, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=33.1658291457286, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI40254992, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=32.4468085106383, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI32455239, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI5031765, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI15277342, Length=275, Percent_Identity=30.1818181818182, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=29.6610169491525, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=29.9242424242424, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI87082100, Length=275, Percent_Identity=30.9090909090909, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=28.2442748091603, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1790717, Length=266, Percent_Identity=25.187969924812, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1789208, Length=266, Percent_Identity=27.8195488721804, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=25.1908396946565, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=30.5343511450382, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=31.4606741573034, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=29.520295202952, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17562906, Length=279, Percent_Identity=31.8996415770609, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=29.9270072992701, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=30.6569343065693, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=276, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=27.0758122743682, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=29.8561151079137, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=28.9377289377289, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.9372693726937, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.8388278388278, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=26.8115942028986, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17563726, Length=292, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI72000259, Length=291, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=26.4925373134328, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193204405, Length=286, Percent_Identity=27.972027972028, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=28.0442804428044, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71994604, Length=268, Percent_Identity=25.7462686567164, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=27.5092936802974, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=24.7474747474747, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=33.9622641509434, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=30.4182509505703, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=30.0751879699248, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI28571526, Length=274, Percent_Identity=26.2773722627737, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27466; Mature: 27466
Theoretical pI: Translated: 8.50; Mature: 8.50
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFI CCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC PGDVRVKADMDALAAETARRHGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVA CCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHH ENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQTAVATFAGGLISASKVLSKE CCCHHHEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH LARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV HHHCCEEEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH VAFLASDESRYLTGATISPTGGLTIH HHHHHCCCCCEEECCEECCCCCEEEC >Mature Secondary Structure MKNLEGKVAIVTGGTGGIGRGVALQLAARGALVVISGRSASKADAVLAELREAGGQGDFI CCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC PGDVRVKADMDALAAETARRHGGIDIVVANAGGNDDEARRPEVRGPFGDIDVARVCAVVA CCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHH ENTAAKLLPVQSALPFLRERGGGAVVFVTSEGGRVPTPTQTAVATFAGGLISASKVLSKE CCCHHHEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH LARDRIRVNCVCVTVVRDSPSWKAAFERTDGVSDRHRKQYEKIIASSPLGVASPEDIGQV HHHCCEEEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH VAFLASDESRYLTGATISPTGGLTIH HHHHHCCCCCEEECCEECCCCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]