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The map label for this gene is yfdE [H]

Identifier: 73541516

GI number: 73541516

Start: 2002178

End: 2003515

Strand: Direct

Name: yfdE [H]

Synonym: Reut_A1827

Alternate gene names: 73541516

Gene position: 2002178-2003515 (Clockwise)

Preceding gene: 73541515

Following gene: 73541517

Centisome position: 52.6

GC content: 69.58

Gene sequence:

>1338_bases
ATGGCAAGTTGGCCGCGCGGCCGGGGCGCTCTACCCTTGCATCAAACTCGTCCGGAAGATGCAAAGGAGACAGCCTTGAA
CACCGAAACCGGCCGCGCCACGGCGGCCACGCAGGACCAACACCCCACCCCCGACCGCCCGCTCCAGGGCGTGCGCGTGC
TGGCCGTGGAGAACTTCGTCGCCGGCCCGTTCGCGTCCATGTGGCTCGCCGACGCGGGCGCCGAGGTCATCAAGGTCGAA
GCCCCGGCCGGCGGCGACTTCGCGCGCAGCACCAGCCCCGTCAGGAGGGCGGAGGACGGCAGCCCGCACGCGCTGTCGTT
CCTGCGCACCAACCGCAACAAGAAGAGCCTGACGCTGGACCTCAAGCAGCCCGAGGGCAAGCGGCTGTTCCTCGAACTGA
TCGCCAGCGCCGACATCGTGATCGAAAACTTGCGCCCGGGCGTCATGGACCGCCTCGGCGTCGGCTACGACACTTTGCGC
GCGCGCAACCCGCGCCTGATCTACGTTGCCATTTCCGGCTTTGGCCACACCGATGTGAAGCCAAGCCCTTACACCGACCA
CCCGGCCCTCGACATCGTCGGCCAGGCGCTCAGCGGCCTGATGTACCGGCCCGAACGGCAGGACGACCGGCCGACCTATC
TCGGCTTTTCGATGACCGACCTGCAGGGCGGCATCCTCGCTGCGCAAGGCGCGCTGCTGGCCCTGTACCAGCGCGAGCGT
ACCGGGCGGGGCAAGAAGGTCGACATTTCGCTGTACGACGCCTCGCTGGTCCAGAACGAGATCTCGGTCACCATGTACTC
GGCCCTGCACCAGCCGCTGCCGCCGGGCGTACCCGCGGTGACAGCGCCGTTCGGGCCGTTCCGCGCCAGCGACGGCCATA
TCGTCATCGCGGTGCTCGGCGAGCACATCTGGCGCCGCTTCTGCGAGGTGATCGGCAAGCCGGACCTGGTGGACGATCCG
CGCTTCGCCGATGGCATCGAGCGCCGCAAGCACAGTGCCGCGCTCGATCCGCATATCGACGCGTGGCTTGCCACGCGCAC
GCGCGCGCAAGCCGTGGACCTGCTGCGCGAGGGCGGCGTGCCAGCGTCGGTGGTCAACGACGTGGCCGACCTGTTCGACT
GCCCGCATGTCGCCGCGCGCGAGATGCTGATGACGGTCCAGGACCCGGCGTGGGGCCCGGTGCAGGTGGTCGGCAACCCG
ATCAAGATGTCGGACGTGCCCGAGCCCGAGGCGAGGGTGCCGCCGCGGCTCGGGGAGCATACCGACGCGGTGCTGCGCGA
CTGGCTACACCTCGATGCGCGGCAGGTCGCCGCGCTGCGCGCCGACGGCATCGTCTGA

Upstream 100 bases:

>100_bases
ACCATCGTGCTGAGCTGACGATGGCGGCCGTCCGAAGCGGGCGAATGTCCGCCGCCCGCTTCGGGTCGTCCTTCGGCTCT
TCCGAATCGCAGCTTCGAAA

Downstream 100 bases:

>100_bases
CCGGAAGACAGTGAAAGCACAGCAAGGAACCAGCAATGAAGAATCTTGAAGGCAAGGTGGCGATCGTCACCGGCGGCACC
GGCGGGATCGGCCGGGGCGT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MASWPRGRGALPLHQTRPEDAKETALNTETGRATAATQDQHPTPDRPLQGVRVLAVENFVAGPFASMWLADAGAEVIKVE
APAGGDFARSTSPVRRAEDGSPHALSFLRTNRNKKSLTLDLKQPEGKRLFLELIASADIVIENLRPGVMDRLGVGYDTLR
ARNPRLIYVAISGFGHTDVKPSPYTDHPALDIVGQALSGLMYRPERQDDRPTYLGFSMTDLQGGILAAQGALLALYQRER
TGRGKKVDISLYDASLVQNEISVTMYSALHQPLPPGVPAVTAPFGPFRASDGHIVIAVLGEHIWRRFCEVIGKPDLVDDP
RFADGIERRKHSAALDPHIDAWLATRTRAQAVDLLREGGVPASVVNDVADLFDCPHVAAREMLMTVQDPAWGPVQVVGNP
IKMSDVPEPEARVPPRLGEHTDAVLRDWLHLDARQVAALRADGIV

Sequences:

>Translated_445_residues
MASWPRGRGALPLHQTRPEDAKETALNTETGRATAATQDQHPTPDRPLQGVRVLAVENFVAGPFASMWLADAGAEVIKVE
APAGGDFARSTSPVRRAEDGSPHALSFLRTNRNKKSLTLDLKQPEGKRLFLELIASADIVIENLRPGVMDRLGVGYDTLR
ARNPRLIYVAISGFGHTDVKPSPYTDHPALDIVGQALSGLMYRPERQDDRPTYLGFSMTDLQGGILAAQGALLALYQRER
TGRGKKVDISLYDASLVQNEISVTMYSALHQPLPPGVPAVTAPFGPFRASDGHIVIAVLGEHIWRRFCEVIGKPDLVDDP
RFADGIERRKHSAALDPHIDAWLATRTRAQAVDLLREGGVPASVVNDVADLFDCPHVAAREMLMTVQDPAWGPVQVVGNP
IKMSDVPEPEARVPPRLGEHTDAVLRDWLHLDARQVAALRADGIV
>Mature_444_residues
ASWPRGRGALPLHQTRPEDAKETALNTETGRATAATQDQHPTPDRPLQGVRVLAVENFVAGPFASMWLADAGAEVIKVEA
PAGGDFARSTSPVRRAEDGSPHALSFLRTNRNKKSLTLDLKQPEGKRLFLELIASADIVIENLRPGVMDRLGVGYDTLRA
RNPRLIYVAISGFGHTDVKPSPYTDHPALDIVGQALSGLMYRPERQDDRPTYLGFSMTDLQGGILAAQGALLALYQRERT
GRGKKVDISLYDASLVQNEISVTMYSALHQPLPPGVPAVTAPFGPFRASDGHIVIAVLGEHIWRRFCEVIGKPDLVDDPR
FADGIERRKHSAALDPHIDAWLATRTRAQAVDLLREGGVPASVVNDVADLFDCPHVAAREMLMTVQDPAWGPVQVVGNPI
KMSDVPEPEARVPPRLGEHTDAVLRDWLHLDARQVAALRADGIV

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=402, Percent_Identity=30.0995024875622, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI300863124, Length=428, Percent_Identity=28.2710280373832, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI300863126, Length=400, Percent_Identity=27.75, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI13376042, Length=428, Percent_Identity=25.4672897196262, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI42794625, Length=409, Percent_Identity=26.161369193154, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI266456254, Length=409, Percent_Identity=26.161369193154, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI266458393, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI266458397, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=37.5, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=37.5, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87082093, Length=366, Percent_Identity=36.6120218579235, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1788717, Length=420, Percent_Identity=29.7619047619048, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1786222, Length=359, Percent_Identity=29.2479108635098, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564160, Length=231, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648431, Length=403, Percent_Identity=32.258064516129, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24585488, Length=210, Percent_Identity=32.3809523809524, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 48506; Mature: 48375

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASWPRGRGALPLHQTRPEDAKETALNTETGRATAATQDQHPTPDRPLQGVRVLAVENFV
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHH
AGPFASMWLADAGAEVIKVEAPAGGDFARSTSPVRRAEDGSPHALSFLRTNRNKKSLTLD
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCEEEEE
LKQPEGKRLFLELIASADIVIENLRPGVMDRLGVGYDTLRARNPRLIYVAISGFGHTDVK
ECCCCCHHHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCC
PSPYTDHPALDIVGQALSGLMYRPERQDDRPTYLGFSMTDLQGGILAAQGALLALYQRER
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECEEHHHCCCCEEHHCCHHHHHHHHHH
TGRGKKVDISLYDASLVQNEISVTMYSALHQPLPPGVPAVTAPFGPFRASDGHIVIAVLG
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEHHH
EHIWRRFCEVIGKPDLVDDPRFADGIERRKHSAALDPHIDAWLATRTRAQAVDLLREGGV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PASVVNDVADLFDCPHVAAREMLMTVQDPAWGPVQVVGNPIKMSDVPEPEARVPPRLGEH
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCCH
TDAVLRDWLHLDARQVAALRADGIV
HHHHHHHHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure 
ASWPRGRGALPLHQTRPEDAKETALNTETGRATAATQDQHPTPDRPLQGVRVLAVENFV
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHH
AGPFASMWLADAGAEVIKVEAPAGGDFARSTSPVRRAEDGSPHALSFLRTNRNKKSLTLD
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCEEEEE
LKQPEGKRLFLELIASADIVIENLRPGVMDRLGVGYDTLRARNPRLIYVAISGFGHTDVK
ECCCCCHHHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCC
PSPYTDHPALDIVGQALSGLMYRPERQDDRPTYLGFSMTDLQGGILAAQGALLALYQRER
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECEEHHHCCCCEEHHCCHHHHHHHHHH
TGRGKKVDISLYDASLVQNEISVTMYSALHQPLPPGVPAVTAPFGPFRASDGHIVIAVLG
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEHHH
EHIWRRFCEVIGKPDLVDDPRFADGIERRKHSAALDPHIDAWLATRTRAQAVDLLREGGV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PASVVNDVADLFDCPHVAAREMLMTVQDPAWGPVQVVGNPIKMSDVPEPEARVPPRLGEH
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCCH
TDAVLRDWLHLDARQVAALRADGIV
HHHHHHHHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]