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The map label for this gene is acoR [H]

Identifier: 73541467

GI number: 73541467

Start: 1940205

End: 1942226

Strand: Direct

Name: acoR [H]

Synonym: Reut_A1778

Alternate gene names: 73541467

Gene position: 1940205-1942226 (Clockwise)

Preceding gene: 73541464

Following gene: 73541468

Centisome position: 50.97

GC content: 66.37

Gene sequence:

>2022_bases
ATGACCATCCCAGCGGAGCCCACTCGCCCTGCCATCTCCGGCGAGACGGGCGACGGGGCTGTCCAACCCGAGCGCGCCGA
ACTGATCGCGCAGGCCCACCAGCGTTCCGCCTCCTATGGCCTGCGCCCGTACGAGTCGCCGGACTTCCGCCCGGTGCTCC
AAAGCGAGCTGAAGACGCGCATCGAACGCAGCCAGTCGCTGTTCACCTACGCGCTGCCGGTAATGGAAACGCTCTACGAC
CAGATCGTGAACACGCAGAGCATGGTGATCCTGACCGACGCCGACGGCCTGATCCTGCACTCGCTGGGCGACGACGATTT
CCTCGCGCGGGCCGACAAGGTGGCGTTGCGTGCCGGTGCCGACTGGTCGGAGGAAAGCCGCGGCACCAACGCCATTGGCA
CCGCGCTGGCCGAGAACCGCGCCACTCTGGTCCACGGCGCGGACCACTTCCTGGAGGCCAACCAGTTTCTGACCTGCTCG
TGCATGACCATCCTTGACGCCTATGGCAAGACGGTCGGGGCGCTCGATGTGACGGGCGACCAGCGTGGCTTTCACAAGCA
CACCATGGCGCTGGTGCGGATGTCGGCACAGATGATCGAAAACCAGCTGTTCGGCAGTGCGTTCCGCGACATGGTCTGCA
TCCACTTTCATTCGCGCGCGGAGTTCCTGGGCACGCTCGTGGAAGGTATCGTCTCTTTCACGCCCGGCGGGCGTTTCCTG
TCGTCGAACCGCAGCGGACATTTCCAGCTGGGCCTGACCAACAAGGCGCTGCAGGCGCATACCTTCTCTTCGCTGTTCGG
GATGCCGTTGTCCCTGTTCTTCGATGCCGTGCGCGGCGCGCCGGCTGGTATCGTGCAGTTGCAACTGCCCAGCGGCGTCA
AGGTCAGCGCGCGCATGGAATGGAAAGCCAGTCCCGCCTCGATGGCCGGCGCGGGTGTGCCCGCGACCACGCCAGATGCC
GTCGCGGCACCGCGGCGACTCTGCCCTGCCCCCGCCAAGCCCGAAGGGCTGGCTGACCTGGACACGGGCGACGCACAGGT
CCGGACCGTGATCGGCAAGCTGCGCAAGGTCATCGGCAAGGACATCCCGGTGATGGTGCTGGGTGAAACCGGCACGGGCA
AGGAACTCATGGCACGCGCCATCCATGCCGACAGCCCGCGCCACGCGGGCCCCTTCATTGCGGTGAACTGCGCGTCGATC
CCGGAGAACCTGATCGAATCGGAGCTGTTCGGTTACGAGGAAGGCGCCTTCACCGGCGCACGCAAGAAAGGCGGCATCGG
CAAGATGCTGCTGGCCAACGGCGGCACGCTGTTCCTGGACGAGATCGGCGACATGCCGCTGCATCTTCAGGGACGCTTGC
TGCGCGCGTTGCAAGAACGCGCTGTCCAGCCGCTGGGCAGCAGCAAGGTGATCCAGGTGGATGTGCTGGTGGTGTGCGCC
ACCAACCGAAACTTGCGCGAGATGGTCGCCAGCGGCCAGTTCCGCGAAGACCTGTACTACCGCCTGAACGGACTTGTGGT
GCGGCTGCCAGCCCTGCGCGAGCGCAGCGATCTCGACGTGGTAGCGGGCAAGCTGCTGCGCCAGGATCAGAGCCAGGGCC
ATGCCAGCGGCGAGCCACCTCGCATCAGCGATGCCGTGATGGAACTGTTCCGGCGATATCACTGGCCCGGCAATATGCGC
CAGCTCGGCAACCTGCTGCGCACGGCGCGGCTGATGGCGGAAGGCGAAGCCGAGATCACGGAAGACCACCTGCCCGACGA
CTTCCTGGACGACTTGCGCGAACGCCAGCAGCAGGCAGCAACGACGGCGGCCCAGGCGGCGCCGGTATCCGCGGTTTTGC
CCGTCGGGCAGGGGGCCGCACAGCCCACGCGGCTCGCCGAGGTCGAAGCGCTTGCCATCGTCGCCGCGGTGAATGCGCAC
CACGGCAATATCTCGGCGGCGGCCAAGGCGCTGGGGATATCGCGCAACACGGTCTATCGAAAGATGGAAGAGGCGCGCGC
GCTGTCGCAACCCCCAGGCTGA

Upstream 100 bases:

>100_bases
TTCATGGCGCCACACTGTCGACGGCCTGCCCGGCGACGGCGATGAAGGCCGGCAGCGACCCGCGCAAAAGATCGCGGGCG
AATTCATAGGAGACCCAGAC

Downstream 100 bases:

>100_bases
TCCCGAACGGCACGAAACAGCAGTGTCCCATTTCTGAACAGGTGTCTCACGCTGAAGCAGTCGTGACACAGCAAGCACGC
AACTGCGTGCTTGCGGTAAA

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MTIPAEPTRPAISGETGDGAVQPERAELIAQAHQRSASYGLRPYESPDFRPVLQSELKTRIERSQSLFTYALPVMETLYD
QIVNTQSMVILTDADGLILHSLGDDDFLARADKVALRAGADWSEESRGTNAIGTALAENRATLVHGADHFLEANQFLTCS
CMTILDAYGKTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFGSAFRDMVCIHFHSRAEFLGTLVEGIVSFTPGGRFL
SSNRSGHFQLGLTNKALQAHTFSSLFGMPLSLFFDAVRGAPAGIVQLQLPSGVKVSARMEWKASPASMAGAGVPATTPDA
VAAPRRLCPAPAKPEGLADLDTGDAQVRTVIGKLRKVIGKDIPVMVLGETGTGKELMARAIHADSPRHAGPFIAVNCASI
PENLIESELFGYEEGAFTGARKKGGIGKMLLANGGTLFLDEIGDMPLHLQGRLLRALQERAVQPLGSSKVIQVDVLVVCA
TNRNLREMVASGQFREDLYYRLNGLVVRLPALRERSDLDVVAGKLLRQDQSQGHASGEPPRISDAVMELFRRYHWPGNMR
QLGNLLRTARLMAEGEAEITEDHLPDDFLDDLRERQQQAATTAAQAAPVSAVLPVGQGAAQPTRLAEVEALAIVAAVNAH
HGNISAAAKALGISRNTVYRKMEEARALSQPPG

Sequences:

>Translated_673_residues
MTIPAEPTRPAISGETGDGAVQPERAELIAQAHQRSASYGLRPYESPDFRPVLQSELKTRIERSQSLFTYALPVMETLYD
QIVNTQSMVILTDADGLILHSLGDDDFLARADKVALRAGADWSEESRGTNAIGTALAENRATLVHGADHFLEANQFLTCS
CMTILDAYGKTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFGSAFRDMVCIHFHSRAEFLGTLVEGIVSFTPGGRFL
SSNRSGHFQLGLTNKALQAHTFSSLFGMPLSLFFDAVRGAPAGIVQLQLPSGVKVSARMEWKASPASMAGAGVPATTPDA
VAAPRRLCPAPAKPEGLADLDTGDAQVRTVIGKLRKVIGKDIPVMVLGETGTGKELMARAIHADSPRHAGPFIAVNCASI
PENLIESELFGYEEGAFTGARKKGGIGKMLLANGGTLFLDEIGDMPLHLQGRLLRALQERAVQPLGSSKVIQVDVLVVCA
TNRNLREMVASGQFREDLYYRLNGLVVRLPALRERSDLDVVAGKLLRQDQSQGHASGEPPRISDAVMELFRRYHWPGNMR
QLGNLLRTARLMAEGEAEITEDHLPDDFLDDLRERQQQAATTAAQAAPVSAVLPVGQGAAQPTRLAEVEALAIVAAVNAH
HGNISAAAKALGISRNTVYRKMEEARALSQPPG
>Mature_672_residues
TIPAEPTRPAISGETGDGAVQPERAELIAQAHQRSASYGLRPYESPDFRPVLQSELKTRIERSQSLFTYALPVMETLYDQ
IVNTQSMVILTDADGLILHSLGDDDFLARADKVALRAGADWSEESRGTNAIGTALAENRATLVHGADHFLEANQFLTCSC
MTILDAYGKTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFGSAFRDMVCIHFHSRAEFLGTLVEGIVSFTPGGRFLS
SNRSGHFQLGLTNKALQAHTFSSLFGMPLSLFFDAVRGAPAGIVQLQLPSGVKVSARMEWKASPASMAGAGVPATTPDAV
AAPRRLCPAPAKPEGLADLDTGDAQVRTVIGKLRKVIGKDIPVMVLGETGTGKELMARAIHADSPRHAGPFIAVNCASIP
ENLIESELFGYEEGAFTGARKKGGIGKMLLANGGTLFLDEIGDMPLHLQGRLLRALQERAVQPLGSSKVIQVDVLVVCAT
NRNLREMVASGQFREDLYYRLNGLVVRLPALRERSDLDVVAGKLLRQDQSQGHASGEPPRISDAVMELFRRYHWPGNMRQ
LGNLLRTARLMAEGEAEITEDHLPDDFLDDLRERQQQAATTAAQAAPVSAVLPVGQGAAQPTRLAEVEALAIVAAVNAHH
GNISAAAKALGISRNTVYRKMEEARALSQPPG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=326, Percent_Identity=42.9447852760736, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=43.5643564356436, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI1788550, Length=304, Percent_Identity=42.1052631578947, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1790299, Length=327, Percent_Identity=40.3669724770642, Blast_Score=205, Evalue=9e-54,
Organism=Escherichia coli, GI1788905, Length=218, Percent_Identity=49.5412844036697, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082117, Length=242, Percent_Identity=43.801652892562, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1789087, Length=320, Percent_Identity=38.4375, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786524, Length=311, Percent_Identity=41.1575562700965, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87082152, Length=308, Percent_Identity=39.2857142857143, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081872, Length=294, Percent_Identity=37.0748299319728, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787583, Length=329, Percent_Identity=35.258358662614, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=606, Percent_Identity=23.4323432343234, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1789828, Length=276, Percent_Identity=34.0579710144928, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72508; Mature: 72376

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPAEPTRPAISGETGDGAVQPERAELIAQAHQRSASYGLRPYESPDFRPVLQSELKTR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IERSQSLFTYALPVMETLYDQIVNTQSMVILTDADGLILHSLGDDDFLARADKVALRAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCC
DWSEESRGTNAIGTALAENRATLVHGADHFLEANQFLTCSCMTILDAYGKTVGALDVTGD
CCCHHCCCCHHHHHHHHCCCEEEEECCHHHHCCCCEEEHHHHHHHHHHCCCEEEEECCCC
QRGFHKHTMALVRMSAQMIENQLFGSAFRDMVCIHFHSRAEFLGTLVEGIVSFTPGGRFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHCCCCCCEE
SSNRSGHFQLGLTNKALQAHTFSSLFGMPLSLFFDAVRGAPAGIVQLQLPSGVKVSARME
CCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEE
WKASPASMAGAGVPATTPDAVAAPRRLCPAPAKPEGLADLDTGDAQVRTVIGKLRKVIGK
ECCCCHHHCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DIPVMVLGETGTGKELMARAIHADSPRHAGPFIAVNCASIPENLIESELFGYEEGAFTGA
CCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCC
RKKGGIGKMLLANGGTLFLDEIGDMPLHLQGRLLRALQERAVQPLGSSKVIQVDVLVVCA
CCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEE
TNRNLREMVASGQFREDLYYRLNGLVVRLPALRERSDLDVVAGKLLRQDQSQGHASGEPP
CCCCHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RISDAVMELFRRYHWPGNMRQLGNLLRTARLMAEGEAEITEDHLPDDFLDDLRERQQQAA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHH
TTAAQAAPVSAVLPVGQGAAQPTRLAEVEALAIVAAVNAHHGNISAAAKALGISRNTVYR
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
KMEEARALSQPPG
HHHHHHHHCCCCC
>Mature Secondary Structure 
TIPAEPTRPAISGETGDGAVQPERAELIAQAHQRSASYGLRPYESPDFRPVLQSELKTR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IERSQSLFTYALPVMETLYDQIVNTQSMVILTDADGLILHSLGDDDFLARADKVALRAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCC
DWSEESRGTNAIGTALAENRATLVHGADHFLEANQFLTCSCMTILDAYGKTVGALDVTGD
CCCHHCCCCHHHHHHHHCCCEEEEECCHHHHCCCCEEEHHHHHHHHHHCCCEEEEECCCC
QRGFHKHTMALVRMSAQMIENQLFGSAFRDMVCIHFHSRAEFLGTLVEGIVSFTPGGRFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHCCCCCCEE
SSNRSGHFQLGLTNKALQAHTFSSLFGMPLSLFFDAVRGAPAGIVQLQLPSGVKVSARME
CCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEE
WKASPASMAGAGVPATTPDAVAAPRRLCPAPAKPEGLADLDTGDAQVRTVIGKLRKVIGK
ECCCCHHHCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DIPVMVLGETGTGKELMARAIHADSPRHAGPFIAVNCASIPENLIESELFGYEEGAFTGA
CCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCC
RKKGGIGKMLLANGGTLFLDEIGDMPLHLQGRLLRALQERAVQPLGSSKVIQVDVLVVCA
CCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEE
TNRNLREMVASGQFREDLYYRLNGLVVRLPALRERSDLDVVAGKLLRQDQSQGHASGEPP
CCCCHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RISDAVMELFRRYHWPGNMRQLGNLLRTARLMAEGEAEITEDHLPDDFLDDLRERQQQAA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHH
TTAAQAAPVSAVLPVGQGAAQPTRLAEVEALAIVAAVNAHHGNISAAAKALGISRNTVYR
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
KMEEARALSQPPG
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]