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The map label for this gene is virS [H]

Identifier: 73541356

GI number: 73541356

Start: 1798253

End: 1799266

Strand: Direct

Name: virS [H]

Synonym: Reut_A1666

Alternate gene names: 73541356

Gene position: 1798253-1799266 (Clockwise)

Preceding gene: 73541354

Following gene: 73541360

Centisome position: 47.24

GC content: 65.48

Gene sequence:

>1014_bases
ATGTCGTCACTTGTCCGCGCCGCAGCCCTCACGAACTTTAATGAGGTCGCTCGTGCCGGCGGCCTGGATCCGGTGCGGAT
GCTGCTCGATGCGGGACTGAGCCCGAGCGCGCTGCGCGAGCCGGACGTCATGATTCCCGTGGAGCGTCTCGGACGCTTGC
TTCAGGCGTGCGCTACCCAGTCTGGCAACGAGAGTTTCGGGCTGTGCATGGCCGAGTCGCGCCTGTTGTCGAATCTCGGT
CCGGTCGGGCTGCTGATCCGCGACCAGCCGACGCTGCGTGACTCGCTTCGGATGCTGATGCGCTATCAGGCGTTGCTCAA
CGGTTCGTTGTCGCTGGCGATCGAGGAGTGCGGCGATCTGGTCATCATCCGCGAAGTGGTCATGGCTGGACATGCGCATG
AGCCCACGCGCCAGAGGGTCGAGCTGGCGCTCGGGGTGATGGTACGGTTGATACGCCAGCTCCACCGGTACGACTGGGAG
CCGGCGCGCGTATGCTTCGAGCACCCGGCGCCGCGCGACCTCAGTGTGCACCAGCGCTTTTTCGGCCCGAACGTCGAGTT
CAACTACGACTTCAACTGCATCCTCTGCACGAAGGCCGATCTCGACGCGCGCAACCCGTATGCCGATCCGGCCATGGCGC
GCTATGTGCAGCAGTTGATCGACGCCACGGCCATGTCGAAGCAGGCCACCATGCTTGAGGACGTCCGCCGCATCGTGCTG
TTGCTGCTGCCCAGCGGCCGGTGCAGCATCGAGCAGGTGTCCGAGCACTTGGGTATCGGGTGCCGCACGGTGCAACGCCG
GCTGGCGGAAGAGGGTCAGCCCTTTTCAGCAGTCGTCAACGACATCCGCACGGAACTCGCGGCGCGCCATGTCATCGAGA
CCGACCGCCCATTGACCGAGGTGGCGACCTTGCTCGGGTTCTCGGCGCCGAGCGGATTCTCGCGCTGGTATCACGCGCAG
TTTGGCTGCAGTCCCAAGGAAAGCCGCGCCGCGCGCGGCAGCGTGCGCCGATAG

Upstream 100 bases:

>100_bases
TCGGATCCTCTCAGTTTGGGCGCTGCAGGCGTTTCCCGCTTGACACTACGTGACAGGCATTTATCCTTAGCTGTCAAATG
CTCACTCACCGCCCCCTCCG

Downstream 100 bases:

>100_bases
GCGGCTTCTTTTCGGATGAGCGTGGATGGCAATGCGGCCGGCGCAAGGGCCGGCCGCATGGGCAAGGGCTTGCCGCTTCA
GCGGCTTACTTGCCGGTCCA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSSLVRAAALTNFNEVARAGGLDPVRMLLDAGLSPSALREPDVMIPVERLGRLLQACATQSGNESFGLCMAESRLLSNLG
PVGLLIRDQPTLRDSLRMLMRYQALLNGSLSLAIEECGDLVIIREVVMAGHAHEPTRQRVELALGVMVRLIRQLHRYDWE
PARVCFEHPAPRDLSVHQRFFGPNVEFNYDFNCILCTKADLDARNPYADPAMARYVQQLIDATAMSKQATMLEDVRRIVL
LLLPSGRCSIEQVSEHLGIGCRTVQRRLAEEGQPFSAVVNDIRTELAARHVIETDRPLTEVATLLGFSAPSGFSRWYHAQ
FGCSPKESRAARGSVRR

Sequences:

>Translated_337_residues
MSSLVRAAALTNFNEVARAGGLDPVRMLLDAGLSPSALREPDVMIPVERLGRLLQACATQSGNESFGLCMAESRLLSNLG
PVGLLIRDQPTLRDSLRMLMRYQALLNGSLSLAIEECGDLVIIREVVMAGHAHEPTRQRVELALGVMVRLIRQLHRYDWE
PARVCFEHPAPRDLSVHQRFFGPNVEFNYDFNCILCTKADLDARNPYADPAMARYVQQLIDATAMSKQATMLEDVRRIVL
LLLPSGRCSIEQVSEHLGIGCRTVQRRLAEEGQPFSAVVNDIRTELAARHVIETDRPLTEVATLLGFSAPSGFSRWYHAQ
FGCSPKESRAARGSVRR
>Mature_336_residues
SSLVRAAALTNFNEVARAGGLDPVRMLLDAGLSPSALREPDVMIPVERLGRLLQACATQSGNESFGLCMAESRLLSNLGP
VGLLIRDQPTLRDSLRMLMRYQALLNGSLSLAIEECGDLVIIREVVMAGHAHEPTRQRVELALGVMVRLIRQLHRYDWEP
ARVCFEHPAPRDLSVHQRFFGPNVEFNYDFNCILCTKADLDARNPYADPAMARYVQQLIDATAMSKQATMLEDVRRIVLL
LLPSGRCSIEQVSEHLGIGCRTVQRRLAEEGQPFSAVVNDIRTELAARHVIETDRPLTEVATLLGFSAPSGFSRWYHAQF
GCSPKESRAARGSVRR

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786758, Length=93, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37476; Mature: 37345

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLVRAAALTNFNEVARAGGLDPVRMLLDAGLSPSALREPDVMIPVERLGRLLQACATQ
CCHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCCEECHHHHHHHHHHHHCC
SGNESFGLCMAESRLLSNLGPVGLLIRDQPTLRDSLRMLMRYQALLNGSLSLAIEECGDL
CCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCC
VIIREVVMAGHAHEPTRQRVELALGVMVRLIRQLHRYDWEPARVCFEHPAPRDLSVHQRF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHH
FGPNVEFNYDFNCILCTKADLDARNPYADPAMARYVQQLIDATAMSKQATMLEDVRRIVL
CCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLPSGRCSIEQVSEHLGIGCRTVQRRLAEEGQPFSAVVNDIRTELAARHVIETDRPLTE
HHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYHAQFGCSPKESRAARGSVRR
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SSLVRAAALTNFNEVARAGGLDPVRMLLDAGLSPSALREPDVMIPVERLGRLLQACATQ
CHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCCEECHHHHHHHHHHHHCC
SGNESFGLCMAESRLLSNLGPVGLLIRDQPTLRDSLRMLMRYQALLNGSLSLAIEECGDL
CCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCC
VIIREVVMAGHAHEPTRQRVELALGVMVRLIRQLHRYDWEPARVCFEHPAPRDLSVHQRF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHH
FGPNVEFNYDFNCILCTKADLDARNPYADPAMARYVQQLIDATAMSKQATMLEDVRRIVL
CCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLPSGRCSIEQVSEHLGIGCRTVQRRLAEEGQPFSAVVNDIRTELAARHVIETDRPLTE
HHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYHAQFGCSPKESRAARGSVRR
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]