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The map label for this gene is tas [H]

Identifier: 73541010

GI number: 73541010

Start: 1411235

End: 1412293

Strand: Reverse

Name: tas [H]

Synonym: Reut_A1316

Alternate gene names: 73541010

Gene position: 1412293-1411235 (Counterclockwise)

Preceding gene: 73541011

Following gene: 73541009

Centisome position: 37.1

GC content: 64.21

Gene sequence:

>1059_bases
ATGGAAACCGTCCGCCTCGGCCGCAGCGACCTGGAGGTCTCCCGCATCTGCCTGGGCACCATGACCTTCGGCGAGCAGAA
CACTGAAGCCGACGGCCACAGCCAGCTCGACTACGCGTTCTCGCGCGGGATCAACTTCATCGATACGGCCGAAATGTACC
CGGTCAGGCCGCGTGCCGAAACCTACAGCCGGACCGAGCAGATCATCGGCAGTTGGCTCAAGCGCCAGCCGCGCGACCGC
GTGGTGCTGGCCACCAAGGTGGCCGGCCCGGGACGGATGCCGTGGATCCGCAATGGCGACGACTTCACCCCGGCGGGCAT
CCTTGCGGCGGTCGACGCATCACTGCAGCGGCTGCAGACCGACTACATCGACCTGTACCAGATCCACTGGCCCGCCCGCA
ACGCGCCGATCTTCGGCCAGACCAGCTTCGATCCGGCCCTGGAACGTCCTTGCGCGTCCATCCAGGCGCAACTGGAAACG
CTGGCGGAGCTGGTGCAGGCCGGCAAGGTTCGTTATGTCGGCGTTTCGAATGAAACGCCATGGGGCGTGAGCGAATTTGT
GCGCCTGGCCGAGCAGCACGGGTTGCCGCGCATTGCGACCATCCAGAACCCCTACAACCTCGTCAACCGCAGCTTTGAGC
AGGGCCTGGACGAGGCTTGCTATCGCACCGACGTGAGCCTGCTGGTCTACAGCCCGCTCGCCTTCGGCCAGCTGACGGGC
AAATACCTGAGCGGCGACCCGGCAAACCCGGTCTTCAACGATGCCGCAATCGGACGCCTGACCCGCTTCGGCGCCGACTG
GAGCCCGCGCTATATGCGCAAGGAAACGATGGCCGCATCGGCGCGCTATGTCGAACTGGCACGCAAGGCCGGATTGTCGC
CGGCGACGCTCGCGCTGGCCTGGTGCTATTCGCGCTGGTTCGCCGCCAGCACCATCATTGGCGCCACGTCGCTGGACCAG
CTACGCGAAAACATCGATGCGTGGCAAACGCAATTGCATGAAGACGTGATTGCCGCAATCGGGGTAATCCACAAGCAAAT
CTGCAATCCTGCGCAATAA

Upstream 100 bases:

>100_bases
GTCTACAGCGGCCTGATCTACCGAGGGCCGACACTCGTACGCGATTGCGCCGCCGCGCTGCGTGCCTGAATCCGTTCTGC
TAGCCAGCAAGGAGAACAAC

Downstream 100 bases:

>100_bases
TCTGCGCCCCGATGGCAAATAAGGGGGCTCCGGCAGCATCGGATGCCCCGCATTCCCTCCGGGACTTCCCATTTCGTGCG
CGAGAAGTGGTATCCTCGCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
METVRLGRSDLEVSRICLGTMTFGEQNTEADGHSQLDYAFSRGINFIDTAEMYPVRPRAETYSRTEQIIGSWLKRQPRDR
VVLATKVAGPGRMPWIRNGDDFTPAGILAAVDASLQRLQTDYIDLYQIHWPARNAPIFGQTSFDPALERPCASIQAQLET
LAELVQAGKVRYVGVSNETPWGVSEFVRLAEQHGLPRIATIQNPYNLVNRSFEQGLDEACYRTDVSLLVYSPLAFGQLTG
KYLSGDPANPVFNDAAIGRLTRFGADWSPRYMRKETMAASARYVELARKAGLSPATLALAWCYSRWFAASTIIGATSLDQ
LRENIDAWQTQLHEDVIAAIGVIHKQICNPAQ

Sequences:

>Translated_352_residues
METVRLGRSDLEVSRICLGTMTFGEQNTEADGHSQLDYAFSRGINFIDTAEMYPVRPRAETYSRTEQIIGSWLKRQPRDR
VVLATKVAGPGRMPWIRNGDDFTPAGILAAVDASLQRLQTDYIDLYQIHWPARNAPIFGQTSFDPALERPCASIQAQLET
LAELVQAGKVRYVGVSNETPWGVSEFVRLAEQHGLPRIATIQNPYNLVNRSFEQGLDEACYRTDVSLLVYSPLAFGQLTG
KYLSGDPANPVFNDAAIGRLTRFGADWSPRYMRKETMAASARYVELARKAGLSPATLALAWCYSRWFAASTIIGATSLDQ
LRENIDAWQTQLHEDVIAAIGVIHKQICNPAQ
>Mature_352_residues
METVRLGRSDLEVSRICLGTMTFGEQNTEADGHSQLDYAFSRGINFIDTAEMYPVRPRAETYSRTEQIIGSWLKRQPRDR
VVLATKVAGPGRMPWIRNGDDFTPAGILAAVDASLQRLQTDYIDLYQIHWPARNAPIFGQTSFDPALERPCASIQAQLET
LAELVQAGKVRYVGVSNETPWGVSEFVRLAEQHGLPRIATIQNPYNLVNRSFEQGLDEACYRTDVSLLVYSPLAFGQLTG
KYLSGDPANPVFNDAAIGRLTRFGADWSPRYMRKETMAASARYVELARKAGLSPATLALAWCYSRWFAASTIIGATSLDQ
LRENIDAWQTQLHEDVIAAIGVIHKQICNPAQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=348, Percent_Identity=28.448275862069, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=28.448275862069, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI27436964, Length=338, Percent_Identity=26.6272189349112, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=26.7267267267267, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=26.7267267267267, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27436971, Length=341, Percent_Identity=26.9794721407625, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718702, Length=326, Percent_Identity=28.8343558282209, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41327764, Length=323, Percent_Identity=27.2445820433437, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI41152114, Length=324, Percent_Identity=27.1604938271605, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789199, Length=355, Percent_Identity=48.4507042253521, Blast_Score=322, Evalue=2e-89,
Organism=Escherichia coli, GI87081735, Length=355, Percent_Identity=31.830985915493, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788070, Length=358, Percent_Identity=31.0055865921788, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=29.0909090909091, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787674, Length=354, Percent_Identity=25.7062146892655, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788081, Length=248, Percent_Identity=30.241935483871, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=27.3026315789474, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=336, Percent_Identity=26.4880952380952, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=367, Percent_Identity=24.2506811989101, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=189, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646159, Length=333, Percent_Identity=28.8288288288288, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646155, Length=343, Percent_Identity=27.6967930029155, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39204; Mature: 39204

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVRLGRSDLEVSRICLGTMTFGEQNTEADGHSQLDYAFSRGINFIDTAEMYPVRPRAE
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCHH
TYSRTEQIIGSWLKRQPRDRVVLATKVAGPGRMPWIRNGDDFTPAGILAAVDASLQRLQT
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQIHWPARNAPIFGQTSFDPALERPCASIQAQLETLAELVQAGKVRYVGVSNETP
HHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
WGVSEFVRLAEQHGLPRIATIQNPYNLVNRSFEQGLDEACYRTDVSLLVYSPLAFGQLTG
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHCC
KYLSGDPANPVFNDAAIGRLTRFGADWSPRYMRKETMAASARYVELARKAGLSPATLALA
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
WCYSRWFAASTIIGATSLDQLRENIDAWQTQLHEDVIAAIGVIHKQICNPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
METVRLGRSDLEVSRICLGTMTFGEQNTEADGHSQLDYAFSRGINFIDTAEMYPVRPRAE
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCHH
TYSRTEQIIGSWLKRQPRDRVVLATKVAGPGRMPWIRNGDDFTPAGILAAVDASLQRLQT
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQIHWPARNAPIFGQTSFDPALERPCASIQAQLETLAELVQAGKVRYVGVSNETP
HHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
WGVSEFVRLAEQHGLPRIATIQNPYNLVNRSFEQGLDEACYRTDVSLLVYSPLAFGQLTG
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHCC
KYLSGDPANPVFNDAAIGRLTRFGADWSPRYMRKETMAASARYVELARKAGLSPATLALA
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
WCYSRWFAASTIIGATSLDQLRENIDAWQTQLHEDVIAAIGVIHKQICNPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]