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The map label for this gene is aroC

Identifier: 73540952

GI number: 73540952

Start: 1342028

End: 1343140

Strand: Direct

Name: aroC

Synonym: Reut_A1257

Alternate gene names: 73540952

Gene position: 1342028-1343140 (Clockwise)

Preceding gene: 73540951

Following gene: 73540953

Centisome position: 35.26

GC content: 67.83

Gene sequence:

>1113_bases
ATGTCCGGCAATACCCTTGGCCTGCTCTTCACTGTCACCACCTTCGGCGAATCGCACGGGCCCGCCATCGGCGCGGTGGT
GGACGGTTGCCCGCCGGGCATGGATCTGACCGAGGCGGATATTCAGGGCGACCTGGACCGCCGCAAGCCGGGCACCTCGC
GGCACGTCACGCAACGCAAGGAACCGGACCAGGTCGAGATCCTGTCGGGCGTGTTCGAAGGCAAGACCACGGGCACGCCG
ATCTGCCTGCTGATCCGCAACACCGACCAGCGCAGCAAGGACTACGGGAATATCGTCGAGACGTTCCGTCCCGGGCATGC
CGACTACACCTACTGGCAGAAGTACGGCATCCGCGACTATCGCGGCGGCGGCCGCTCGTCGGCCCGCCTGACCGCACCGG
TCGTGGCGGCGGGCGCCGTGGCCAAGAAGTGGCTGCGCGAGCAGTTCGGCACGGAAATCCGCGGCTATATGTCGAAGCTG
GGCGAGATCGAGGTGCCGTTCAGCGACTGGTCGCATGTGCCCGAGAACCCGTTCTTCGCCGCCAATGCGGACATCGTTCC
GGAACTCGAAACCTATATGGACGCGCTGCGCCGCGACGGCGATTCGGTCGGCGCGCGCATCGAAGTTGTTGCCAGCAATG
TGCCAGTGGGCCTTGGCGAGCCGCTGTTCGATCGCCTCGATGCCGATATCGCGCATGCGATGATGGGCCTCAACGCGGTC
AAGGGCGTGGAGATTGGCGCCGGCTTCAAGAGCGTGGAGCAGCGCGGCAGCGAACACGGCGACGAGCTTACCGCGCAGGG
CTTCCGAGGCAACAACGCAGGCGGCATCCTCGGCGGCATTTCCACGGGCCAGGACATCACCGTGTCGCTGGCGATCAAGC
CGACCTCCAGCATCCGCACGCCGCGCGAGTCGATCGACAAGGCCGGCAATGCCGCGACGGTCGAGACCTTCGGCCGCCAC
GATCCGTGCGTGGGCATCCGCGCGACGCCGATCGCCGAGGCGCTGCTCGCGCTCGTGCTGGTCGACCACGCGCTGCGCCA
CCGCGCGCAGTGCGGCGACGTCAAGGTGGACACGCCGCGCATCCCCGCGCAGGCCCCTGGCCAGCCCGGCTGA

Upstream 100 bases:

>100_bases
CAGCGGCGACCTGTCGCGCCGCTGAGCGGCAAGCGGGCGCAGAACCGGCGGCAATGGCCTTACAATGTAGGCCGTCCCCA
ATTTCTGTGCGGTTTCCATC

Downstream 100 bases:

>100_bases
GTTGGCCGCGGCGCCCGAGACCGTCAGCGCCGTTCCGGCGCGGCCCGAATATGGCCGCTTCGGTCTCTTCTACCTGGGGT
ACTACGGCTACGTCGGCGTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMDLTEADIQGDLDRRKPGTSRHVTQRKEPDQVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPVVAAGAVAKKWLREQFGTEIRGYMSKL
GEIEVPFSDWSHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASNVPVGLGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFKSVEQRGSEHGDELTAQGFRGNNAGGILGGISTGQDITVSLAIKPTSSIRTPRESIDKAGNAATVETFGRH
DPCVGIRATPIAEALLALVLVDHALRHRAQCGDVKVDTPRIPAQAPGQPG

Sequences:

>Translated_370_residues
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMDLTEADIQGDLDRRKPGTSRHVTQRKEPDQVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPVVAAGAVAKKWLREQFGTEIRGYMSKL
GEIEVPFSDWSHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASNVPVGLGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFKSVEQRGSEHGDELTAQGFRGNNAGGILGGISTGQDITVSLAIKPTSSIRTPRESIDKAGNAATVETFGRH
DPCVGIRATPIAEALLALVLVDHALRHRAQCGDVKVDTPRIPAQAPGQPG
>Mature_369_residues
SGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMDLTEADIQGDLDRRKPGTSRHVTQRKEPDQVEILSGVFEGKTTGTPI
CLLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPVVAAGAVAKKWLREQFGTEIRGYMSKLG
EIEVPFSDWSHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASNVPVGLGEPLFDRLDADIAHAMMGLNAVK
GVEIGAGFKSVEQRGSEHGDELTAQGFRGNNAGGILGGISTGQDITVSLAIKPTSSIRTPRESIDKAGNAATVETFGRHD
PCVGIRATPIAEALLALVLVDHALRHRAQCGDVKVDTPRIPAQAPGQPG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=65.8333333333333, Blast_Score=467, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=42.7792915531335, Blast_Score=285, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CUPPJ (Q472Q5)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295472.1
- HSSP:   P63611
- ProteinModelPortal:   Q472Q5
- SMR:   Q472Q5
- GeneID:   3609149
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A1257
- NMPDR:   fig|264198.3.peg.1904
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   REUT264198:REUT_A1257-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39511; Mature: 39380

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMDLTEADIQGDLDRRKPGTSRHVTQRK
CCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHCCCHHHCCCCCCCCCCCCC
EPDQVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCC
RGGGRSSARLTAPVVAAGAVAKKWLREQFGTEIRGYMSKLGEIEVPFSDWSHVPENPFFA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
ANADIVPELETYMDALRRDGDSVGARIEVVASNVPVGLGEPLFDRLDADIAHAMMGLNAV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFKSVEQRGSEHGDELTAQGFRGNNAGGILGGISTGQDITVSLAIKPTSSIRT
CCCEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHCCC
PRESIDKAGNAATVETFGRHDPCVGIRATPIAEALLALVLVDHALRHRAQCGDVKVDTPR
CHHHHHHCCCCEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
IPAQAPGQPG
CCCCCCCCCC
>Mature Secondary Structure 
SGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMDLTEADIQGDLDRRKPGTSRHVTQRK
CCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHCCCHHHCCCCCCCCCCCCC
EPDQVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCC
RGGGRSSARLTAPVVAAGAVAKKWLREQFGTEIRGYMSKLGEIEVPFSDWSHVPENPFFA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
ANADIVPELETYMDALRRDGDSVGARIEVVASNVPVGLGEPLFDRLDADIAHAMMGLNAV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFKSVEQRGSEHGDELTAQGFRGNNAGGILGGISTGQDITVSLAIKPTSSIRT
CCCEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHCCC
PRESIDKAGNAATVETFGRHDPCVGIRATPIAEALLALVLVDHALRHRAQCGDVKVDTPR
CHHHHHHCCCCEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
IPAQAPGQPG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA