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The map label for this gene is hcaT [H]

Identifier: 73540953

GI number: 73540953

Start: 1343142

End: 1344410

Strand: Direct

Name: hcaT [H]

Synonym: Reut_A1258

Alternate gene names: 73540953

Gene position: 1343142-1344410 (Clockwise)

Preceding gene: 73540952

Following gene: 73540956

Centisome position: 35.29

GC content: 67.06

Gene sequence:

>1269_bases
TTGGCCGCGGCGCCCGAGACCGTCAGCGCCGTTCCGGCGCGGCCCGAATATGGCCGCTTCGGTCTCTTCTACCTGGGGTA
CTACGGCTACGTCGGCGTGATTTCGCCGTTCGTCAGCCTGTTCTTCGCCGCGCGCGGCTTCAACGCCGTGCAGATCGGCG
TGCTGATGGCCTCATTCCAGTTCAGCCGCATCCTCGGCCCGTACCTGTGGGGTTGGCTTTCGGACATGATGCACACGCGC
GTGCGCATCCTGCGTTTCACGGCCGTGGGCGCACTCGCCGCGTTCCTTGCGCTGCCGGCCGTGCATAGCTACGGCGGCAT
GATGGCAATGATGGTGGCCATCAGCCTCATCACCAGCGCGATGTCGCCGCTCGGCGATGCCCTGACCATTTCCACGCTGC
GCCGCTACGGCGCGTTTGACCACCGCTATGGCCGCATCCGCATGTTCGGCTCGGTCGGTTTCATCGCAGCCGTATTGGCA
GGCGGCGCGCTGTTCCAGCAACTCGGCATGCAGACCTTTCCATGGGTCGCCAGCACGATGCTCGCGATCCTGATGGCGAT
GGTGTTCGGCATGCGCGACGCGCCCGACGAGGGTCCGCGCGTGCGACCGCCGCCCGCACTGCCGTTGCTGCGGCGGCCCG
ATGTGGCGTGGTTCTTCGCGTCGGCGTTCCTGATGATGTTCGCGCACGCGGCGCTGTACGTGTTCTATTCACTCTATCTG
GAGCGGCTGGGGTACAGCAAGTTTGCGATCGGCGTGATGTGGACGATCGGCGTGGTTGCCGAGATCGTGTTCTTCTATTT
CCAGGGCCGGTTGTTCGCGCGGGTGCCGCTCGGGACGATCCTGGCCGGGACCTTCGTGCTGGCCGCGGTGCGATTTGGGC
TGACCGGCTACTTTCCGGAAGCGCTGTGGCTGATGGCCGCCGTGCAGGTGCTCCACGCCGCCACGTTTGCCGCGCACCAC
AGCGCCAGCCTCAAGCGCCTGCAGCACTGGTTCGCCGGGCCGCTGCAGGGCAGGGGACAGGCGCTGTACACGGGGATTTC
CTACGGCGTTGGCGGCACACTGGGTGGGCTGGTGATGGGCTGGACCTGGAAGGCGCTCGCCCCCGCGCATACCTTCGGTC
TTGCGGCGGCCGCTGCTGCCGCGGGTGCCATCTGTGCCGCGATGAGTTTCCGTAGCGGCTCGGGCGCGGCTCAGGACAAT
TCGGCGGCCACGCGTTCGGCGATGGCCAGCGACGAGGTCAGCCCCGGGGACTCGATGCCGAACAGGTGA

Upstream 100 bases:

>100_bases
GTGCTGGTCGACCACGCGCTGCGCCACCGCGCGCAGTGCGGCGACGTCAAGGTGGACACGCCGCGCATCCCCGCGCAGGC
CCCTGGCCAGCCCGGCTGAG

Downstream 100 bases:

>100_bases
ACCAGTCCAGGCACGCCGTGCACCGCGGGGCCATCGATGCGGAAATCGGCGGCAACTTCATGCGGGCCACTGATCTTCGG
ACGGATGCCGGCATAGCCGG

Product: MFS family nucleoside/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MAAAPETVSAVPARPEYGRFGLFYLGYYGYVGVISPFVSLFFAARGFNAVQIGVLMASFQFSRILGPYLWGWLSDMMHTR
VRILRFTAVGALAAFLALPAVHSYGGMMAMMVAISLITSAMSPLGDALTISTLRRYGAFDHRYGRIRMFGSVGFIAAVLA
GGALFQQLGMQTFPWVASTMLAILMAMVFGMRDAPDEGPRVRPPPALPLLRRPDVAWFFASAFLMMFAHAALYVFYSLYL
ERLGYSKFAIGVMWTIGVVAEIVFFYFQGRLFARVPLGTILAGTFVLAAVRFGLTGYFPEALWLMAAVQVLHAATFAAHH
SASLKRLQHWFAGPLQGRGQALYTGISYGVGGTLGGLVMGWTWKALAPAHTFGLAAAAAAAGAICAAMSFRSGSGAAQDN
SAATRSAMASDEVSPGDSMPNR

Sequences:

>Translated_422_residues
MAAAPETVSAVPARPEYGRFGLFYLGYYGYVGVISPFVSLFFAARGFNAVQIGVLMASFQFSRILGPYLWGWLSDMMHTR
VRILRFTAVGALAAFLALPAVHSYGGMMAMMVAISLITSAMSPLGDALTISTLRRYGAFDHRYGRIRMFGSVGFIAAVLA
GGALFQQLGMQTFPWVASTMLAILMAMVFGMRDAPDEGPRVRPPPALPLLRRPDVAWFFASAFLMMFAHAALYVFYSLYL
ERLGYSKFAIGVMWTIGVVAEIVFFYFQGRLFARVPLGTILAGTFVLAAVRFGLTGYFPEALWLMAAVQVLHAATFAAHH
SASLKRLQHWFAGPLQGRGQALYTGISYGVGGTLGGLVMGWTWKALAPAHTFGLAAAAAAAGAICAAMSFRSGSGAAQDN
SAATRSAMASDEVSPGDSMPNR
>Mature_421_residues
AAAPETVSAVPARPEYGRFGLFYLGYYGYVGVISPFVSLFFAARGFNAVQIGVLMASFQFSRILGPYLWGWLSDMMHTRV
RILRFTAVGALAAFLALPAVHSYGGMMAMMVAISLITSAMSPLGDALTISTLRRYGAFDHRYGRIRMFGSVGFIAAVLAG
GALFQQLGMQTFPWVASTMLAILMAMVFGMRDAPDEGPRVRPPPALPLLRRPDVAWFFASAFLMMFAHAALYVFYSLYLE
RLGYSKFAIGVMWTIGVVAEIVFFYFQGRLFARVPLGTILAGTFVLAAVRFGLTGYFPEALWLMAAVQVLHAATFAAHHS
ASLKRLQHWFAGPLQGRGQALYTGISYGVGGTLGGLVMGWTWKALAPAHTFGLAAAAAAAGAICAAMSFRSGSGAAQDNS
AATRSAMASDEVSPGDSMPNR

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=344, Percent_Identity=29.6511627906977, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45334; Mature: 45203

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure 
AAAPETVSAVPARPEYGRFGLFYLGYYGYVGVISPFVSLFFAARGFNAVQIGVLMASFQ
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FSRILGPYLWGWLSDMMHTRVRILRFTAVGALAAFLALPAVHSYGGMMAMMVAISLITSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSPLGDALTISTLRRYGAFDHRYGRIRMFGSVGFIAAVLAGGALFQQLGMQTFPWVASTM
HHHCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LAILMAMVFGMRDAPDEGPRVRPPPALPLLRRPDVAWFFASAFLMMFAHAALYVFYSLYL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGYSKFAIGVMWTIGVVAEIVFFYFQGRLFARVPLGTILAGTFVLAAVRFGLTGYFPE
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCHH
ALWLMAAVQVLHAATFAAHHSASLKRLQHWFAGPLQGRGQALYTGISYGVGGTLGGLVMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHCCCHHHHHHHHH
WTWKALAPAHTFGLAAAAAAAGAICAAMSFRSGSGAAQDNSAATRSAMASDEVSPGDSMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
NR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]