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The map label for this gene is kipR [H]

Identifier: 73540934

GI number: 73540934

Start: 1323336

End: 1324094

Strand: Direct

Name: kipR [H]

Synonym: Reut_A1239

Alternate gene names: 73540934

Gene position: 1323336-1324094 (Clockwise)

Preceding gene: 73540932

Following gene: 73540935

Centisome position: 34.76

GC content: 69.57

Gene sequence:

>759_bases
ATGACTTACATCGTTGACGCCGTCGACGAGGCGCTTGGCCTGCTGATGCTGGTGGCCAAGCATCCGTCCCTGGGCGTGAC
CGAGCTCGCGCGCCGGGCCGGGCTCACCAAGGCGCGCGCGTTCCGGCTGCTGAGCACGCTCGAGCATCGCGGCATGATCG
CGCGCGAAGCGCCGGCCGCGGTTTACAAGCTCAGCTACAACGCCTTGCTGGTCGGCAATGCCGCGCGCGAGCAAGTCGAC
CTGATCAAGCTCGTCACGCCAAGCCTGGCCGCGCTGGGCGCCGCCTGCGGCGAGAACGTGATCGTGCGCGTGCGCGACGG
GCTCGAATCGGTCTGCGTGGCGCGCCATGAGTCGTCGCAGTCGGTGCGCGTGCATACCGAGGTTGGCAACCGCCGTCCGC
TGCATGTGGGAGCTTCCGGCAAGCTTCTGCTCGCCTATGGCGGGGACGTGCTGATCGATGCGGTGCTGGCGAACGCACTG
CAGCGCTTCACCGACAAGACCATCGTCGATCCGCAGGCGCTGCGCGACGAACTCGCGGCCATCCGTGCGGCGGGCTATGC
GGTGTCTCTGGGCGAGCGCGAGCCCGACGCCGTGTCCGCCGCGGCGCCGCTGCGTGACCACAGCGGCAGCACCGTCGCCT
CGCTGAGCATTGCGAGCCCGGCCAGCCGCACGACGCAGGAAGTGCTGGACCGCCACGTGGCCATGGTCGTCGAACAGGCG
GCTGTGTTGTCGCGCTCGCTCGGCTACTCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGGTCTTGCCCTGGCAACTGCCTTCGCCGATGCGGCGCCACCTCGTCCTGCCCGCTACAATGCGCGCTGAACCCCGTTT
CACCCATAACAAAGAACCCG

Downstream 100 bases:

>100_bases
TCCTACCGGCCGGCAGGCCAGCAGGTTACCGCAGCAGCGGCAACCAACTCCGGTTTTCCCTATCCCTTCACCCCGGCAAT
GACTGTTGCCGGGGCGTCTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTYIVDAVDEALGLLMLVAKHPSLGVTELARRAGLTKARAFRLLSTLEHRGMIAREAPAAVYKLSYNALLVGNAAREQVD
LIKLVTPSLAALGAACGENVIVRVRDGLESVCVARHESSQSVRVHTEVGNRRPLHVGASGKLLLAYGGDVLIDAVLANAL
QRFTDKTIVDPQALRDELAAIRAAGYAVSLGEREPDAVSAAAPLRDHSGSTVASLSIASPASRTTQEVLDRHVAMVVEQA
AVLSRSLGYSGA

Sequences:

>Translated_252_residues
MTYIVDAVDEALGLLMLVAKHPSLGVTELARRAGLTKARAFRLLSTLEHRGMIAREAPAAVYKLSYNALLVGNAAREQVD
LIKLVTPSLAALGAACGENVIVRVRDGLESVCVARHESSQSVRVHTEVGNRRPLHVGASGKLLLAYGGDVLIDAVLANAL
QRFTDKTIVDPQALRDELAAIRAAGYAVSLGEREPDAVSAAAPLRDHSGSTVASLSIASPASRTTQEVLDRHVAMVVEQA
AVLSRSLGYSGA
>Mature_251_residues
TYIVDAVDEALGLLMLVAKHPSLGVTELARRAGLTKARAFRLLSTLEHRGMIAREAPAAVYKLSYNALLVGNAAREQVDL
IKLVTPSLAALGAACGENVIVRVRDGLESVCVARHESSQSVRVHTEVGNRRPLHVGASGKLLLAYGGDVLIDAVLANALQ
RFTDKTIVDPQALRDELAAIRAAGYAVSLGEREPDAVSAAAPLRDHSGSTVASLSIASPASRTTQEVLDRHVAMVVEQAA
VLSRSLGYSGA

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=29.2682926829268, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=27.8225806451613, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786715, Length=224, Percent_Identity=29.4642857142857, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=27.8884462151394, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789999, Length=245, Percent_Identity=27.3469387755102, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788581, Length=246, Percent_Identity=24.7967479674797, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26547; Mature: 26416

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYIVDAVDEALGLLMLVAKHPSLGVTELARRAGLTKARAFRLLSTLEHRGMIAREAPAA
CCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCE
VYKLSYNALLVGNAAREQVDLIKLVTPSLAALGAACGENVIVRVRDGLESVCVARHESSQ
EEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCC
SVRVHTEVGNRRPLHVGASGKLLLAYGGDVLIDAVLANALQRFTDKTIVDPQALRDELAA
CEEEEECCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IRAAGYAVSLGEREPDAVSAAAPLRDHSGSTVASLSIASPASRTTQEVLDRHVAMVVEQA
HHHCCEEEECCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
AVLSRSLGYSGA
HHHHHHCCCCCC
>Mature Secondary Structure 
TYIVDAVDEALGLLMLVAKHPSLGVTELARRAGLTKARAFRLLSTLEHRGMIAREAPAA
CEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCE
VYKLSYNALLVGNAAREQVDLIKLVTPSLAALGAACGENVIVRVRDGLESVCVARHESSQ
EEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCC
SVRVHTEVGNRRPLHVGASGKLLLAYGGDVLIDAVLANALQRFTDKTIVDPQALRDELAA
CEEEEECCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IRAAGYAVSLGEREPDAVSAAAPLRDHSGSTVASLSIASPASRTTQEVLDRHVAMVVEQA
HHHCCEEEECCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
AVLSRSLGYSGA
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]