Click here to switch to the map view.

The map label for this gene is comA [H]

Identifier: 73540781

GI number: 73540781

Start: 1170084

End: 1172486

Strand: Direct

Name: comA [H]

Synonym: Reut_A1079

Alternate gene names: 73540781

Gene position: 1170084-1172486 (Clockwise)

Preceding gene: 73540780

Following gene: 73540783

Centisome position: 30.74

GC content: 68.54

Gene sequence:

>2403_bases
GTGCGCCTGATCCTGCTGGGTTTCGTGGTCGGCTGCTGGGCCTTGCAGCGGCAGGGCTCGCTGCCTGCGTACAGCGCGCT
GGGTTTCGCCTCTGCCGCACTCGCAATCCTCGTCGTCTGGCTGGTCCGGTACGGAGGCAACAAGCGGCTCGCACACGGAC
TCGCGATTCTGGTGGCGGTCTCAGTGGGCTTCTGCTGGGCGGCGTGGCGCGCGCATTCGCGCATGGGCGACTGGCTGCCC
ACGCAGCTGGAGGCGCGCGATATCGAGGTGACCGGCGTGGTCTCCGGCCTGCCTGCCGAACTGTCGCCCGGCGCCCGCTT
TGCCTTCACGGTCGAGGCCGCGCAGCACGGCGAACAAGTGCCGGCCCGCGTGCAGCTGAGCTGGCGCGAGGCCACGCCTG
AGCTACGCCCCGGCCAGCGCTACACCTTCACGGTGCGCTTGCGTCGTCCGCGCGGGCTCGCCAATCCCCACGGTTTCGAC
TACGCATACTGGCTGCTGGCGCAAGGCTATGGCGCGACGGGTTACGTGCGTACCGTCCACAACGGGCCGCAGGAAGCGGC
GCACGAACGGATCGCATGGCGCATCGGGGCGCAACGTGCCACGTTGCGCGACCACATCCGCGCCGCGCTGCCCGCGGACG
CCCGTTTCGCGCCGGTGCTTGTGGCGCTCGTCGTCGGCGACCAGCGCGGCATCGATGGCGATGATTGGCTGCTGTTCAAT
CGCACTGGCATCGGCCACCTCGTCAGCATTTCCGGACTCCATATCACGATGATCGCGGGCTTTGCCGCGGGCCTGGTGCA
ATGGGCGTGGCGGCATTCATTCGGGTTAGGCCGCCGTCTGCGCCGGCCGTTGCCGCTGTGGTGTCCGGCGCGGCAGGCGG
CGCTCGTTGCGGCAGTGCTCGCGGGGCTGGGATACGGCCTGATCGCCGGTCTGCAAATTCCGGCACTGCGTACGGTGGCC
ATGCTGTCCATCGCCGCGCTGGCCGCGTGGAGCGCTCGGACGCCACCGGCATCGATGGTGCTCGCGTGGGCGGCTTTCGT
CGCGCTGCTGCTGGACCCGTGGGCGGTGACGCAACCGGGGTTCTGGTTGTCGTTCGGTGCGGTCGGCGTGATCTTCCTGG
CGGCATCGCGTCCTCACGTGCCGGTGCGCGGGTGGTGGCCACGCATACGCGCGGCGCTCCTCTCCGCAGCGCGCACGCAA
TGGGCTGTAACGGTCGGTCTGGTGCCGCTGACGTTGCTGCTCTTCCGGCAGTTTCCGGTCATTTCCCCGATTGCGAATGC
TGTTGCCATTCCCGTGGTCAGCATGTTCGTCACGCCGCTTGCGCTGCTCGGTGCGGTGGTACCGATGACGCTGGCCGCGC
CATTGCTGGTGTTGGCGCATGGGGCGCTGGCGTGGCTGGTGCTTGTGCTGCAGTGGCTGGCATCGTCCGAGTGGGCGGTC
TGGGAGACGGCGCAGGCCGGCGTGCTGGAAACGGTGTTGGCGCTGGCTGGCACGCTCATCCTGCTGGCACCTGCCGTGTT
CGGATTGCGCATACGGCTGCACGGGGTGCTGTTGATCCTGCCTATGGTGGTCGCGCGCGGCGACGATGTGGCGCATGGCG
AATTCCGGGCCGCGATGCTCGATGTCGGGCAGGGCACCGCGGTGCTGGTGCAAACGCGCGCGCACGCCTTGCTTTACGAC
GCCGGGCCAGCCTATGCCTCCGGGGGCAGCGCCGGAGCGCAGGTCATCGTGCCCTATCTGCGCGCGTTCGGCATACGCAG
GCTCGACCATTTGATGGTCAGCCACGAAGATGCCGACCACGCGGGTGGCGCGCGCCACGTCATCGATGCCGTGTCCGTCG
ATATCCGGTCCACGGCCGCGCCGGCCGGCCATGCGCTGCTTGGCAAGGCCGATTGGGTGGCATGCGTGGCGGGCGAGCAC
TGGGAGTGGGATGGCGTCCATTTCACGGTGCTGCATCCAGACGCCGGGCAATCGCGCGATGCGGCGATCGGGAGCAATGC
GCGCAGTTGCGTACTGCGCGTGGACAACGGCCGCCATAGCGTGCTGCTGACTGGCGATATCGGCAAGGCGGAAGAGCGCG
AACTGGTCGAGCGGATACCTGCGGAGAGGCTGCGTGCCGATGTCCTCGTCGTGCCGCACCATGGCAGCGGCACCTCATCC
AGTTCCGAGTGGCTCGCGGCCGTCAGTCCCGGCGCGGCGGTGTTCCAACTCGGCTACCGCAACCGCTATCAGCATCCGCG
CGCCGATGTCTGGCAGCGTTATGGCGATGCCGGCATTCTGCGCTACCGCACGGACGAAACCGGTGCAGTCACGATGACCA
CGCACCGTGACGCCTATGCGATGGAAGCGTTTCGCCAGGCCGAGCGTCGCTACTGGCGTGAGGCGCCTGCAGCGCCGCGA
TAG

Upstream 100 bases:

>100_bases
GGCGCCTGACATTTCCGACACCAACTTCTGACACGCTGACAAGCTTTTCACGGCAAGGCGAGGGTACAACGATGGCCCTC
TGAACTTGCCGGGGAGCTTC

Downstream 100 bases:

>100_bases
CGGAAGGTGGCGTTAGCTCGCGGTGCGAGCGCGTGCACGCGACGCCGTCTTGCGCCCGGGCGCCGCCGGCTCTGGCGTAT
CAGCTTCCTGTGGCGCCCGC

Product: ComEC/Rec2-related protein:DNA internalization-related competence protein ComEC/Rec2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 800; Mature: 800

Protein sequence:

>800_residues
MRLILLGFVVGCWALQRQGSLPAYSALGFASAALAILVVWLVRYGGNKRLAHGLAILVAVSVGFCWAAWRAHSRMGDWLP
TQLEARDIEVTGVVSGLPAELSPGARFAFTVEAAQHGEQVPARVQLSWREATPELRPGQRYTFTVRLRRPRGLANPHGFD
YAYWLLAQGYGATGYVRTVHNGPQEAAHERIAWRIGAQRATLRDHIRAALPADARFAPVLVALVVGDQRGIDGDDWLLFN
RTGIGHLVSISGLHITMIAGFAAGLVQWAWRHSFGLGRRLRRPLPLWCPARQAALVAAVLAGLGYGLIAGLQIPALRTVA
MLSIAALAAWSARTPPASMVLAWAAFVALLLDPWAVTQPGFWLSFGAVGVIFLAASRPHVPVRGWWPRIRAALLSAARTQ
WAVTVGLVPLTLLLFRQFPVISPIANAVAIPVVSMFVTPLALLGAVVPMTLAAPLLVLAHGALAWLVLVLQWLASSEWAV
WETAQAGVLETVLALAGTLILLAPAVFGLRIRLHGVLLILPMVVARGDDVAHGEFRAAMLDVGQGTAVLVQTRAHALLYD
AGPAYASGGSAGAQVIVPYLRAFGIRRLDHLMVSHEDADHAGGARHVIDAVSVDIRSTAAPAGHALLGKADWVACVAGEH
WEWDGVHFTVLHPDAGQSRDAAIGSNARSCVLRVDNGRHSVLLTGDIGKAEERELVERIPAERLRADVLVVPHHGSGTSS
SSEWLAAVSPGAAVFQLGYRNRYQHPRADVWQRYGDAGILRYRTDETGAVTMTTHRDAYAMEAFRQAERRYWREAPAAPR

Sequences:

>Translated_800_residues
MRLILLGFVVGCWALQRQGSLPAYSALGFASAALAILVVWLVRYGGNKRLAHGLAILVAVSVGFCWAAWRAHSRMGDWLP
TQLEARDIEVTGVVSGLPAELSPGARFAFTVEAAQHGEQVPARVQLSWREATPELRPGQRYTFTVRLRRPRGLANPHGFD
YAYWLLAQGYGATGYVRTVHNGPQEAAHERIAWRIGAQRATLRDHIRAALPADARFAPVLVALVVGDQRGIDGDDWLLFN
RTGIGHLVSISGLHITMIAGFAAGLVQWAWRHSFGLGRRLRRPLPLWCPARQAALVAAVLAGLGYGLIAGLQIPALRTVA
MLSIAALAAWSARTPPASMVLAWAAFVALLLDPWAVTQPGFWLSFGAVGVIFLAASRPHVPVRGWWPRIRAALLSAARTQ
WAVTVGLVPLTLLLFRQFPVISPIANAVAIPVVSMFVTPLALLGAVVPMTLAAPLLVLAHGALAWLVLVLQWLASSEWAV
WETAQAGVLETVLALAGTLILLAPAVFGLRIRLHGVLLILPMVVARGDDVAHGEFRAAMLDVGQGTAVLVQTRAHALLYD
AGPAYASGGSAGAQVIVPYLRAFGIRRLDHLMVSHEDADHAGGARHVIDAVSVDIRSTAAPAGHALLGKADWVACVAGEH
WEWDGVHFTVLHPDAGQSRDAAIGSNARSCVLRVDNGRHSVLLTGDIGKAEERELVERIPAERLRADVLVVPHHGSGTSS
SSEWLAAVSPGAAVFQLGYRNRYQHPRADVWQRYGDAGILRYRTDETGAVTMTTHRDAYAMEAFRQAERRYWREAPAAPR
>Mature_800_residues
MRLILLGFVVGCWALQRQGSLPAYSALGFASAALAILVVWLVRYGGNKRLAHGLAILVAVSVGFCWAAWRAHSRMGDWLP
TQLEARDIEVTGVVSGLPAELSPGARFAFTVEAAQHGEQVPARVQLSWREATPELRPGQRYTFTVRLRRPRGLANPHGFD
YAYWLLAQGYGATGYVRTVHNGPQEAAHERIAWRIGAQRATLRDHIRAALPADARFAPVLVALVVGDQRGIDGDDWLLFN
RTGIGHLVSISGLHITMIAGFAAGLVQWAWRHSFGLGRRLRRPLPLWCPARQAALVAAVLAGLGYGLIAGLQIPALRTVA
MLSIAALAAWSARTPPASMVLAWAAFVALLLDPWAVTQPGFWLSFGAVGVIFLAASRPHVPVRGWWPRIRAALLSAARTQ
WAVTVGLVPLTLLLFRQFPVISPIANAVAIPVVSMFVTPLALLGAVVPMTLAAPLLVLAHGALAWLVLVLQWLASSEWAV
WETAQAGVLETVLALAGTLILLAPAVFGLRIRLHGVLLILPMVVARGDDVAHGEFRAAMLDVGQGTAVLVQTRAHALLYD
AGPAYASGGSAGAQVIVPYLRAFGIRRLDHLMVSHEDADHAGGARHVIDAVSVDIRSTAAPAGHALLGKADWVACVAGEH
WEWDGVHFTVLHPDAGQSRDAAIGSNARSCVLRVDNGRHSVLLTGDIGKAEERELVERIPAERLRADVLVVPHHGSGTSS
SSEWLAAVSPGAAVFQLGYRNRYQHPRADVWQRYGDAGILRYRTDETGAVTMTTHRDAYAMEAFRQAERRYWREAPAAPR

Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=660, Percent_Identity=29.2424242424242, Blast_Score=198, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 86355; Mature: 86355

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILLGFVVGCWALQRQGSLPAYSALGFASAALAILVVWLVRYGGNKRLAHGLAILVAV
CEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVGFCWAAWRAHSRMGDWLPTQLEARDIEVTGVVSGLPAELSPGARFAFTVEAAQHGEQV
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEHHHCCCCC
PARVQLSWREATPELRPGQRYTFTVRLRRPRGLANPHGFDYAYWLLAQGYGATGYVRTVH
CEEEEEEEHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECC
NGPQEAAHERIAWRIGAQRATLRDHIRAALPADARFAPVLVALVVGDQRGIDGDDWLLFN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCCCCCEEEEE
RTGIGHLVSISGLHITMIAGFAAGLVQWAWRHSFGLGRRLRRPLPLWCPARQAALVAAVL
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AGLGYGLIAGLQIPALRTVAMLSIAALAAWSARTPPASMVLAWAAFVALLLDPWAVTQPG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
FWLSFGAVGVIFLAASRPHVPVRGWWPRIRAALLSAARTQWAVTVGLVPLTLLLFRQFPV
CCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCC
ISPIANAVAIPVVSMFVTPLALLGAVVPMTLAAPLLVLAHGALAWLVLVLQWLASSEWAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
WETAQAGVLETVLALAGTLILLAPAVFGLRIRLHGVLLILPMVVARGDDVAHGEFRAAML
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEE
DVGQGTAVLVQTRAHALLYDAGPAYASGGSAGAQVIVPYLRAFGIRRLDHLMVSHEDADH
ECCCCCEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGGARHVIDAVSVDIRSTAAPAGHALLGKADWVACVAGEHWEWDGVHFTVLHPDAGQSRD
CCCHHHHHHHHHCCHHHCCCCCCCEEECCCCEEEEECCCCCEECCEEEEEECCCCCCCCC
AAIGSNARSCVLRVDNGRHSVLLTGDIGKAEERELVERIPAERLRADVLVVPHHGSGTSS
CCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCHHHHCCCEEEEECCCCCCCC
SSEWLAAVSPGAAVFQLGYRNRYQHPRADVWQRYGDAGILRYRTDETGAVTMTTHRDAYA
CCCEEEEECCCHHHEEECHHCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHH
MEAFRQAERRYWREAPAAPR
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLILLGFVVGCWALQRQGSLPAYSALGFASAALAILVVWLVRYGGNKRLAHGLAILVAV
CEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVGFCWAAWRAHSRMGDWLPTQLEARDIEVTGVVSGLPAELSPGARFAFTVEAAQHGEQV
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEHHHCCCCC
PARVQLSWREATPELRPGQRYTFTVRLRRPRGLANPHGFDYAYWLLAQGYGATGYVRTVH
CEEEEEEEHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECC
NGPQEAAHERIAWRIGAQRATLRDHIRAALPADARFAPVLVALVVGDQRGIDGDDWLLFN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCCCCCEEEEE
RTGIGHLVSISGLHITMIAGFAAGLVQWAWRHSFGLGRRLRRPLPLWCPARQAALVAAVL
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AGLGYGLIAGLQIPALRTVAMLSIAALAAWSARTPPASMVLAWAAFVALLLDPWAVTQPG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
FWLSFGAVGVIFLAASRPHVPVRGWWPRIRAALLSAARTQWAVTVGLVPLTLLLFRQFPV
CCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCC
ISPIANAVAIPVVSMFVTPLALLGAVVPMTLAAPLLVLAHGALAWLVLVLQWLASSEWAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
WETAQAGVLETVLALAGTLILLAPAVFGLRIRLHGVLLILPMVVARGDDVAHGEFRAAML
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEE
DVGQGTAVLVQTRAHALLYDAGPAYASGGSAGAQVIVPYLRAFGIRRLDHLMVSHEDADH
ECCCCCEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGGARHVIDAVSVDIRSTAAPAGHALLGKADWVACVAGEHWEWDGVHFTVLHPDAGQSRD
CCCHHHHHHHHHCCHHHCCCCCCCEEECCCCEEEEECCCCCEECCEEEEEECCCCCCCCC
AAIGSNARSCVLRVDNGRHSVLLTGDIGKAEERELVERIPAERLRADVLVVPHHGSGTSS
CCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCHHHHCCCEEEEECCCCCCCC
SSEWLAAVSPGAAVFQLGYRNRYQHPRADVWQRYGDAGILRYRTDETGAVTMTTHRDAYA
CCCEEEEECCCHHHEEECHHCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHH
MEAFRQAERRYWREAPAAPR
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934834; 8830266 [H]