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The map label for this gene is yjjV [H]

Identifier: 73540780

GI number: 73540780

Start: 1169159

End: 1169992

Strand: Direct

Name: yjjV [H]

Synonym: Reut_A1078

Alternate gene names: 73540780

Gene position: 1169159-1169992 (Clockwise)

Preceding gene: 73540779

Following gene: 73540781

Centisome position: 30.71

GC content: 66.55

Gene sequence:

>834_bases
ATGTGGATCGACACCCATTGCCATCTCGATGCCCGTGAATTCGATGCGGATCGCGGCCGGGTTGCCGACGCCGCCGAGGC
CGCCGGCGTAACCGGCATCGTTGTGCCGGCCGTGGCGGTGTGGAACTTCGACACAGTTCGCACGCTGGCCCGGCAGGATG
AACGCTGCGTCTATGCGCTCGGCATTCATCCGCTATGCTCGCCGGGCGCGGCGCAGGCCGATGTCGATGCGTTGCGCAGG
GAGGTGGCGGCCTCGATGTCTGATCCTCGCTTCGTCGGCATCGGCGAGATCGGACTCGACTTCTTTGTCGCCGGTCTGGA
TGTCGACCACCAGACCTGGCTCTACATCGAACAGCTCAAGATCGCGCGCGAATTCGACCTGCCGGTGCTGCTGCACGTGC
GCAAGTCGCAGGACCAGGTTGGCGCGCAACTGCGCAAGCTCGGGGTGCGGCAGGGGATCGCACACGCCTTTAATGGCAGT
CATGAGCAGGCACGCCGCTTTATCGACCAGGGGTTCAAGCTCGGCTTTGGCGGCAACGTGACGTTCAGCCGCGCGCGGCA
GATCCGCCGGCTCGCCACCGAGTTGCCGCTTGACGCGCTGGTGCTGGAAACCGACGCGCCCGATATCGCGCCCGCGTGGC
TGTCCGACGACCAGTTCGGGGAGCAGCACAAGGCCCGGAATACGCCTGCCGAAGTGGCTGGCGTCGCACGGGTACTTGGG
GAGTTGCGAGAGATGGAGCCGGATGCTTTGGCGCAAGCCATGTGGCGCAATTCGGTCGCCGCGCTGCCCCGCTTGGCGGC
ATTCGCCGAGGCGATGGCGCCGGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
TGTCATCGTCACGCACGACTTGGACCTGGCCGGCCGCTGCGACCGCGTACTGCGGCTGCGCGACGGGCACCTTCACCAGG
AGCGGTGACCGCGTACGGCT

Downstream 100 bases:

>100_bases
CATTTCCGACACCAACTTCTGACACGCTGACAAGCTTTTCACGGCAAGGCGAGGGTACAACGATGGCCCTCTGAACTTGC
CGGGGAGCTTCGTGCGCCTG

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MWIDTHCHLDAREFDADRGRVADAAEAAGVTGIVVPAVAVWNFDTVRTLARQDERCVYALGIHPLCSPGAAQADVDALRR
EVAASMSDPRFVGIGEIGLDFFVAGLDVDHQTWLYIEQLKIAREFDLPVLLHVRKSQDQVGAQLRKLGVRQGIAHAFNGS
HEQARRFIDQGFKLGFGGNVTFSRARQIRRLATELPLDALVLETDAPDIAPAWLSDDQFGEQHKARNTPAEVAGVARVLG
ELREMEPDALAQAMWRNSVAALPRLAAFAEAMAPAGA

Sequences:

>Translated_277_residues
MWIDTHCHLDAREFDADRGRVADAAEAAGVTGIVVPAVAVWNFDTVRTLARQDERCVYALGIHPLCSPGAAQADVDALRR
EVAASMSDPRFVGIGEIGLDFFVAGLDVDHQTWLYIEQLKIAREFDLPVLLHVRKSQDQVGAQLRKLGVRQGIAHAFNGS
HEQARRFIDQGFKLGFGGNVTFSRARQIRRLATELPLDALVLETDAPDIAPAWLSDDQFGEQHKARNTPAEVAGVARVLG
ELREMEPDALAQAMWRNSVAALPRLAAFAEAMAPAGA
>Mature_277_residues
MWIDTHCHLDAREFDADRGRVADAAEAAGVTGIVVPAVAVWNFDTVRTLARQDERCVYALGIHPLCSPGAAQADVDALRR
EVAASMSDPRFVGIGEIGLDFFVAGLDVDHQTWLYIEQLKIAREFDLPVLLHVRKSQDQVGAQLRKLGVRQGIAHAFNGS
HEQARRFIDQGFKLGFGGNVTFSRARQIRRLATELPLDALVLETDAPDIAPAWLSDDQFGEQHKARNTPAEVAGVARVLG
ELREMEPDALAQAMWRNSVAALPRLAAFAEAMAPAGA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=273, Percent_Identity=26.3736263736264, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=26.3736263736264, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI226061853, Length=278, Percent_Identity=25.5395683453237, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226061614, Length=265, Percent_Identity=25.6603773584906, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=224, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI225903439, Length=233, Percent_Identity=24.4635193133047, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI14042943, Length=233, Percent_Identity=24.4635193133047, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=38.3720930232558, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787342, Length=263, Percent_Identity=31.5589353612167, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI48994985, Length=244, Percent_Identity=28.2786885245902, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=23.8636363636364, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559024, Length=278, Percent_Identity=23.3812949640288, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330018, Length=213, Percent_Identity=30.5164319248826, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24586117, Length=213, Percent_Identity=30.5164319248826, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648690, Length=278, Percent_Identity=25.1798561151079, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30239; Mature: 30239

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIDTHCHLDAREFDADRGRVADAAEAAGVTGIVVPAVAVWNFDTVRTLARQDERCVYAL
CCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEE
GIHPLCSPGAAQADVDALRREVAASMSDPRFVGIGEIGLDFFVAGLDVDHQTWLYIEQLK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHEEECCCCCCHHHHHHHHHH
IAREFDLPVLLHVRKSQDQVGAQLRKLGVRQGIAHAFNGSHEQARRFIDQGFKLGFGGNV
HHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCC
TFSRARQIRRLATELPLDALVLETDAPDIAPAWLSDDQFGEQHKARNTPAEVAGVARVLG
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCHHHHCCCCHHHHHHHHHHHH
ELREMEPDALAQAMWRNSVAALPRLAAFAEAMAPAGA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWIDTHCHLDAREFDADRGRVADAAEAAGVTGIVVPAVAVWNFDTVRTLARQDERCVYAL
CCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEE
GIHPLCSPGAAQADVDALRREVAASMSDPRFVGIGEIGLDFFVAGLDVDHQTWLYIEQLK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHEEECCCCCCHHHHHHHHHH
IAREFDLPVLLHVRKSQDQVGAQLRKLGVRQGIAHAFNGSHEQARRFIDQGFKLGFGGNV
HHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCC
TFSRARQIRRLATELPLDALVLETDAPDIAPAWLSDDQFGEQHKARNTPAEVAGVARVLG
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCHHHHCCCCHHHHHHHHHHHH
ELREMEPDALAQAMWRNSVAALPRLAAFAEAMAPAGA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]