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The map label for this gene is yngJ [H]

Identifier: 73540705

GI number: 73540705

Start: 1088618

End: 1089880

Strand: Reverse

Name: yngJ [H]

Synonym: Reut_A1002

Alternate gene names: 73540705

Gene position: 1089880-1088618 (Counterclockwise)

Preceding gene: 73540709

Following gene: 73540704

Centisome position: 28.63

GC content: 64.77

Gene sequence:

>1263_bases
ATGCAATTCGAATACACGCCCAAGGTCAAGGAGATGCAGGCCAAGCTGTTGGCCTTCTTCGACCAGTACATCTACCCGAA
CGAAAAGCGCTTCTACGAAGAGATCAACGCCAACCGCCAGGCTGGTAACGCGTGGGTGCCGAGCAAGCTGATCGAGGAAC
TGAAGCCCAAGGCACGTGAAGCCGGCCTGTGGAACCTGTTCCTGCCGCGTTCGCCGCGCGCGCCGCAGGGCCTGTCGAAC
CTCGAATACGCAACGCTGTGCGAAATCATGGGCCGGGTGCCCTGGTCGGCCGAAGTTTTCAACTGCGCCGCGCCCGACAC
CGGCAACATGGAAACGCTCGAGCGCTACGCGTCCGAAGAACTGAAGGACAAATGGCTCGAGCCGCTGCTTGCGGGCGAGA
TCCGCTCGGCCTTCCTGATGACCGAGCCGGCCGTGGCTTCGTCGGACGCCACCAATATCGAATGCCGCATCGAGCGTGAT
GGCGACCATTACGTGGTCAACGGCACCAAGTGGTGGTCGTCGGGCGCCGGCGATCCGCGCTGCAAGGTCTACATCGTGAT
GGGCAAGACCGATCCGAGCGCGGGCCGCCACGAGCAGCAGTCCATGATCGTGGTGCCGGCCGACACCCCGGGCATCACCA
TCAAGCGTTTCCTGCCGGTGTTCGGTTATGACGACGCGCCGCACGGCCATATGGAAATCGAGCTGAAGAACGTGCGCGTG
CCGGTCTCGAACATCCTGCTCGGCGAAGGCCGGGGCTTCGAGATCGCGCAGGGTCGCCTCGGCCCGGGCCGTATCCACCA
CTGCATGCGCAGCATCGGCGTGGCCGAACGCGCGCTGGAACTGCTGTGCAAGCGCGCACTGTCGCGGGTGGCGTTCGGCA
AGCCAGTCGCCAACCAGGGCGTCACGCAGGAGCGCATTGCCGAAGCGCGCTGCGAAATCGAGATGGCCCGCCTGCTCACG
CTCAGGGCCGCCTACATGATGGACACGGTCGGCAACAAGATCGCCAAGGCCGAGATCGCCATGATCAAGGTAGTGGCCCC
GAACGTCGCCCTGAAGGTGATCGACTGGGCGATCCAGGTGCACGGCGCGGCCGGCGTATCGAGCGACTTCCCGCTGGCCA
ACTGGTGGGCGCACCAGCGCACGCTGCGCCTGGCCGACGGTCCGGACGAGGTGCACCGCAACGCCATCGCCAAGCTGGAA
CTGGCCAAGCACATGGGCCTGAAGCCGGAAGACGTGAAGATGCCCGTGGCACGCGGCTTCTGA

Upstream 100 bases:

>100_bases
CGGATAGAGTGCTTTCCATCGGCATATGCCGCGTACTGTCCGTACCAACCCGTGCTGCCGGGGCCACCGGCGCACCACTA
CCTGGTAGCGAGGAGACCCC

Downstream 100 bases:

>100_bases
GTCCAGCCCGACACACGCGCCGGCAACCCCGTCGGCAGTATGGAAACGCGCAGCCCCGCTGCGCGTTTTTTTCTTCTGTG
CTTAAATCGATCGATCCTTT

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQFEYTPKVKEMQAKLLAFFDQYIYPNEKRFYEEINANRQAGNAWVPSKLIEELKPKAREAGLWNLFLPRSPRAPQGLSN
LEYATLCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDKWLEPLLAGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVVNGTKWWSSGAGDPRCKVYIVMGKTDPSAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELLCKRALSRVAFGKPVANQGVTQERIAEARCEIEMARLLT
LRAAYMMDTVGNKIAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMGLKPEDVKMPVARGF

Sequences:

>Translated_420_residues
MQFEYTPKVKEMQAKLLAFFDQYIYPNEKRFYEEINANRQAGNAWVPSKLIEELKPKAREAGLWNLFLPRSPRAPQGLSN
LEYATLCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDKWLEPLLAGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVVNGTKWWSSGAGDPRCKVYIVMGKTDPSAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELLCKRALSRVAFGKPVANQGVTQERIAEARCEIEMARLLT
LRAAYMMDTVGNKIAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMGLKPEDVKMPVARGF
>Mature_420_residues
MQFEYTPKVKEMQAKLLAFFDQYIYPNEKRFYEEINANRQAGNAWVPSKLIEELKPKAREAGLWNLFLPRSPRAPQGLSN
LEYATLCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDKWLEPLLAGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVVNGTKWWSSGAGDPRCKVYIVMGKTDPSAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELLCKRALSRVAFGKPVANQGVTQERIAEARCEIEMARLLT
LRAAYMMDTVGNKIAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMGLKPEDVKMPVARGF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=57.356608478803, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=57.3200992555831, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=57.3200992555831, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI21361497, Length=391, Percent_Identity=29.156010230179, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4557231, Length=411, Percent_Identity=26.5206812652068, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI187960098, Length=411, Percent_Identity=26.5206812652068, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4501859, Length=322, Percent_Identity=29.5031055900621, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557233, Length=321, Percent_Identity=30.8411214953271, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7656849, Length=344, Percent_Identity=27.6162790697674, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI76496475, Length=413, Percent_Identity=27.6029055690073, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4557235, Length=413, Percent_Identity=27.6029055690073, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI226958412, Length=323, Percent_Identity=25.6965944272446, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=25.6172839506173, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=24.6006389776358, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=305, Percent_Identity=27.8688524590164, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786223, Length=298, Percent_Identity=24.1610738255034, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=54.5205479452055, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534899, Length=405, Percent_Identity=29.3827160493827, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=413, Percent_Identity=27.6029055690073, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=351, Percent_Identity=28.4900284900285, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17570075, Length=287, Percent_Identity=27.5261324041812, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=284, Percent_Identity=30.2816901408451, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=389, Percent_Identity=27.5064267352185, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=408, Percent_Identity=25.7352941176471, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=358, Percent_Identity=26.8156424581006, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=318, Percent_Identity=26.1006289308176, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=398, Percent_Identity=23.3668341708543, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=28.0898876404494, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=311, Percent_Identity=25.08038585209, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=179, Percent_Identity=29.608938547486, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=27.9352226720648, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=278, Percent_Identity=24.4604316546763, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646207, Length=348, Percent_Identity=30.4597701149425, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281363737, Length=400, Percent_Identity=28, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=31.5972222222222, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24660351, Length=345, Percent_Identity=29.5652173913043, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=29.1553133514986, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355753, Length=291, Percent_Identity=26.1168384879725, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920834, Length=321, Percent_Identity=25.5451713395639, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 46858; Mature: 46858

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFEYTPKVKEMQAKLLAFFDQYIYPNEKRFYEEINANRQAGNAWVPSKLIEELKPKARE
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHH
AGLWNLFLPRSPRAPQGLSNLEYATLCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEE
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHH
LKDKWLEPLLAGEIRSAFLMTEPAVASSDATNIECRIERDGDHYVVNGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKTDPSAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCCCCCEEEEEEEEEEC
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELLCKRALSRVAFGKPVANQG
CHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTQERIAEARCEIEMARLLTLRAAYMMDTVGNKIAKAEIAMIKVVAPNVALKVIDWAIQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHHEEEEEEEEE
HGAAGVSSDFPLANWWAHQRTLRLADGPDEVHRNAIAKLELAKHMGLKPEDVKMPVARGF
ECCCCCCCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MQFEYTPKVKEMQAKLLAFFDQYIYPNEKRFYEEINANRQAGNAWVPSKLIEELKPKARE
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHH
AGLWNLFLPRSPRAPQGLSNLEYATLCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEE
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHH
LKDKWLEPLLAGEIRSAFLMTEPAVASSDATNIECRIERDGDHYVVNGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKTDPSAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCCCCCEEEEEEEEEEC
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELLCKRALSRVAFGKPVANQG
CHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTQERIAEARCEIEMARLLTLRAAYMMDTVGNKIAKAEIAMIKVVAPNVALKVIDWAIQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHHEEEEEEEEE
HGAAGVSSDFPLANWWAHQRTLRLADGPDEVHRNAIAKLELAKHMGLKPEDVKMPVARGF
ECCCCCCCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]