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The map label for this gene is nuoH [H]

Identifier: 73540671

GI number: 73540671

Start: 1056474

End: 1057538

Strand: Direct

Name: nuoH [H]

Synonym: Reut_A0968

Alternate gene names: 73540671

Gene position: 1056474-1057538 (Clockwise)

Preceding gene: 73540670

Following gene: 73540672

Centisome position: 27.75

GC content: 61.31

Gene sequence:

>1065_bases
ATGATCGACTGGATTACCTCGCAAGGCCACGCCATCTTCGGCGGCGCTTGGACGCCGCTGTGGATCCTGATTCGGGCCGT
GCTCATTGTGGTGCCGCTGCTGCTGTGCGTGGCCTACCTGATTCTGTGGGAGCGCAAGCTGATCGGCTGGATGCACGTGC
GTCTGGGGCCGAACCGCGTCGGCCCGCTGGGCCTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTCAAAGAAGTC
ATGACGCCGACGCACGTCAGCAAGGGCATGTACCTGATTGCCCCGCTGATGGTGCTGATGCCTGCGGTTGCCATTTGGGC
CGTGATCCCGTTCCAGGCGGAAGTGGTGATGGCCGACGTGAATGCCGGTCTGCTGTACGTGATGGCGATCAGCTCGGTCG
GCGTGTACGGCGTGATCCTGGCCGGCTGGGCCTCGAACTCCAAGTACGCGTTCCTGGGCGGCATGCGCGCTGCCGCGCAG
ATGGTGTCGTATGAAATCGCCATGGGCTTCGCGCTGGTGACGGTGCTGATGGTGTCGGGCAGCCTGAACCTGTCGGCGAT
CGTGAACAGCCAGAACACCGGCTACTTCGCGAACATGGGCATCAACGTGCTGTCGTGGAACTGGATTCCGCTGCTGCCGA
TGTTCGGCGTGTACTTCATCTCGGGCGTGGCCGAAACCAACCGCCACCCGTTCGACGTGGTGGAAGGCGAATCGGAAATC
GTGGCAGGTCACATGATCGAATACTCGGGCATGGCGTTCGCGCTGTTCTTCCTGGCTGAGTACATCAACATGATCATCAT
CTCGACGATCACGGCGCTGCTGTTCCTCGGCGGCTGGGCGCCTCCGTTCTCGAGCTTCGTGACCAATGCGATCCCCGGCT
TCTTCTGGCTGCTGATCAAGGTATTCCTGCTGCTGTCGGTTTTCATCTGGATTCGTGCCTCGTTCCCGCGCTACCGCTAT
GACCAGATCATGCGCCTGGGCTGGAAGGTGTTCATTCCGCTGACCGTGGGCTGGCTGATCATCGTGGCGATCTGGATCAA
GTCGCCTTGGAACATCTGGCACTGA

Upstream 100 bases:

>100_bases
CACGGTCAAGGTCGAGAAGGCTGTCGACCTGTCCGCCGGCCAGAAGGCCGCTGCAACGGCCGGCGCGGCCTGAGCCATAC
AAGAATAGCGAGAACGCAAC

Downstream 100 bases:

>100_bases
ACGGCCAGGCGAGGGCGCGCACGCCGCAACGATACGGTGCGCCCCTCCGGAAATACTAGGAAGCAATCGTCATGCTGCTC
GCCATCAAGGACTTCTTCAA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIDWITSQGHAIFGGAWTPLWILIRAVLIVVPLLLCVAYLILWERKLIGWMHVRLGPNRVGPLGLLQPIADVLKLLLKEV
MTPTHVSKGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADVNAGLLYVMAISSVGVYGVILAGWASNSKYAFLGGMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSAIVNSQNTGYFANMGINVLSWNWIPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIIISTITALLFLGGWAPPFSSFVTNAIPGFFWLLIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKVFIPLTVGWLIIVAIWIKSPWNIWH

Sequences:

>Translated_354_residues
MIDWITSQGHAIFGGAWTPLWILIRAVLIVVPLLLCVAYLILWERKLIGWMHVRLGPNRVGPLGLLQPIADVLKLLLKEV
MTPTHVSKGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADVNAGLLYVMAISSVGVYGVILAGWASNSKYAFLGGMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSAIVNSQNTGYFANMGINVLSWNWIPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIIISTITALLFLGGWAPPFSSFVTNAIPGFFWLLIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKVFIPLTVGWLIIVAIWIKSPWNIWH
>Mature_354_residues
MIDWITSQGHAIFGGAWTPLWILIRAVLIVVPLLLCVAYLILWERKLIGWMHVRLGPNRVGPLGLLQPIADVLKLLLKEV
MTPTHVSKGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADVNAGLLYVMAISSVGVYGVILAGWASNSKYAFLGGMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSAIVNSQNTGYFANMGINVLSWNWIPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMAFALFFLAEYINMIIISTITALLFLGGWAPPFSSFVTNAIPGFFWLLIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKVFIPLTVGWLIIVAIWIKSPWNIWH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=317, Percent_Identity=41.9558359621451, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI1788618, Length=324, Percent_Identity=40.4320987654321, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39446; Mature: 39446

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDWITSQGHAIFGGAWTPLWILIRAVLIVVPLLLCVAYLILWERKLIGWMHVRLGPNRV
CCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPLGLLQPIADVLKLLLKEVMTPTHVSKGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADV
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFLGGMRAAAQMVSYEIAMGFALVTVLMVSG
CCCHHHHHHHHHCCHHHHHEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLNLSAIVNSQNTGYFANMGINVLSWNWIPLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCEEEEEECCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMAFALFFLAEYINMIIISTITALLFLGGWAPPFSSFVTNAIPGFFWLLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFLLLSVFIWIRASFPRYRYDQIMRLGWKVFIPLTVGWLIIVAIWIKSPWNIWH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIDWITSQGHAIFGGAWTPLWILIRAVLIVVPLLLCVAYLILWERKLIGWMHVRLGPNRV
CCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPLGLLQPIADVLKLLLKEVMTPTHVSKGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADV
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFLGGMRAAAQMVSYEIAMGFALVTVLMVSG
CCCHHHHHHHHHCCHHHHHEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLNLSAIVNSQNTGYFANMGINVLSWNWIPLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCEEEEEECCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMAFALFFLAEYINMIIISTITALLFLGGWAPPFSSFVTNAIPGFFWLLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFLLLSVFIWIRASFPRYRYDQIMRLGWKVFIPLTVGWLIIVAIWIKSPWNIWH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA