Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 73540670

GI number: 73540670

Start: 1054071

End: 1056446

Strand: Direct

Name: nuoG [H]

Synonym: Reut_A0967

Alternate gene names: 73540670

Gene position: 1054071-1056446 (Clockwise)

Preceding gene: 73540669

Following gene: 73540671

Centisome position: 27.69

GC content: 66.37

Gene sequence:

>2376_bases
ATGGTTGAACTCGAGATCGACGGCAAGAAGGTTGAGGTTGCAGAAGGCAGCCTGGTGATGGAAGCCGCCCGCAAGCTGGG
CACCTACATCCCGCACTTCTGCTACCACCGCAAACTGTCCATCGCGGCCAACTGCCGCATGTGTCTGGTTGAAGTTGAAA
AGGCGCCCAAGGCGCTGCCGGCTTGCGCCACCCCGGTGACCCCGGGCATGAAGGTCTTCACCAATTCGGAGAAGGCCGTC
AAGGCGCAGAAGTCCGTGATGGAATTCCTGCTGATCAACCACCCGCTCGACTGCCCGATCTGCGATCAGGGCGGCGAATG
CCAGCTGCAGGATCTGGCCGTGGGCTATGGTGCTTCAGAGTCGCGCTACAAAGAAGAGAAGCGCGTGGTGTTCCACAAGA
ATGTGGGCCCGCTGATCTCCATGGAAGAGATGACCCGCTGCATTCACTGCACCCGCTGCGTGCGCTTTGGCCAGGAAGTG
GCCGGCGTGATGGAGCTGGGCATGCTGAACCGCGGAGAGCACTCGGAAATCACGACCTTCGTCGGCCAGACCGTGGACTC
GGAACTGTCCGGCAACATGATCGACCTGTGCCCGGTCGGCGCGTTGACCAGCAAGCCATTCCGCTACTCGGCCCGTACGT
GGGAGCTCGCACGCCGCAAGTCGGTGTCGCCGCACGACGGCCTGGGTGCCAACCTGGTCGTCCAGAGCAAGAACCAGCGC
GTCATGCGCGTGCTGCCGCTCGAGAACGAAGACGTCAACGAGTGCTGGATCTCGGACAAGGACCGCTTCTCGTATGAAGG
CCTGAACAGTGCCGACCGTCTGACGCGCCCGCTGCTGAAGCAGGGCGGCCAGTGGATCGAAACCGACTGGCAGACCGCGC
TCGAATACGTGGCCAATGGCCTGTCGAGCATCAAGCGCGACCATGGCGCCGACCAGATCGCTGCGCTGGCCAGCCCGCAC
AGCACGCTGGAAGAGCTGTACTTGCTCGGCAAGCTGATGCGCGGCATTGGTAGCGACAACGTCGACTTCCGTCTGCGCCA
GTCCGATTTCTCGGCAGCGCTGAAGGGCGCGCCTTGGCTTGGCATGCCGGTGGCCGATGTGTCCACGCTGCAACGCGTGC
TGGTGATCGGTTCGTCGCTGCGCAAAGACCACCCGTTGCTGGCCTCGCGTCTGCGCCAGGCAGGCAAGAAGGGCGCCCGC
GTCGCCGTGCTCGGTGCAGGCGGTGAAGACCTGCTGATGCCGTTGGCCGCGCGTATCGACGTGGCCCCGTCGGGCTGGAC
CGCTGCGCTGGCTGGTATCGCCCGTGCCGTGGCGACCGCCAAGGGCGTCGCCGCACCGGCAGGCACCGAAGGTTTTGACG
GTGGCGATGCCGCCCGTGCCGCCGCCGACGCGCTGCTGTCGGGCGAGCGCCGCGCCGTGTTCCTCGGCAACGAGGCCGTG
CGTCATCCGCAGTTCGCTGCGCTGCACGCGCTGGCACAGTGGATCGCTACGGAAGCCGGCGCCACGCTGGGCTTCCTGAC
CGAGGCTGCAAACACCGTGGGTGGCTATGTCGCCGGTGCGCTGCCGAAGCAGGGCGGTGCCAACGCGCAGGCGATGCTGG
AATCGCCGCGCAAGGCCTACGTGCTGCTCAACACGGAACCTGAGTTCGACGCCGCCGACCCGCGCAAGGCCTTGGCCGCG
CTGGCCCAGGCTGGCACCGTGGTCGTATTGTCGCCGTTCCGCTCGGAAGCGGCCATGCAGTATGCCGACGTGATCCTGCC
GGTTACGCCGTTCACCGAAACTGCGGGTACCTTCGTCAACTGCGAAGGCCTGCCGCAGAGCTTCAATGGCGTGGTGCGCG
CGCTCGGCGAATCCCGTCCGGCCTGGAAGGTACTGCGTGTGCTGGGCAACCTGCTGGACGTGGCCGGTTTCGACTACGAC
AGCGCCGAAGCAGTTCGCGCCGAAGTGCTGGCCAACCCGGTTGCACCGCAACTGAGCAACGCCACCGACGCGCCGATCCG
GGTGAGCGCCGCCGCTGCCAATGGCATCGAGCGTATTGCAGATGTGCCGATCTACCACGCCGATCCGATCGTGCGCCGTG
CCGAATCGCTGCAGCTGACCGCCGCGGCCCGTCGCGCGCAGCAAGTGGCGCTGTCCGCCGATCTGTTCGCCGGTCTGGGT
ATCCAATCGGGCGACCCGGTCCGCGTGACGCAGGGCGAGGGTAGCGTGGTGCTGCCGGGCGTGCTGGAAAACACGCTGCC
GGCCAACACTGTGCGCGTTCCGGCTGCAACCCCGGCGGCAATGAGCCTCGGCGCCATGTTCGGCACGGTCAAGGTCGAGA
AGGCTGTCGACCTGTCCGCCGGCCAGAAGGCCGCTGCAACGGCCGGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGGTCCGCGGCATGCTCAAGCACTACTGGAAAGAGTTCGAATATCACGTCGAACACAAGCAGTGCATGGTTCCGGCCT
ACATCTAAGCGTGGCAGAAC

Downstream 100 bases:

>100_bases
GCCATACAAGAATAGCGAGAACGCAACATGATCGACTGGATTACCTCGCAAGGCCACGCCATCTTCGGCGGCGCTTGGAC
GCCGCTGTGGATCCTGATTC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MVELEIDGKKVEVAEGSLVMEAARKLGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTPGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGASESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANLVVQSKNQR
VMRVLPLENEDVNECWISDKDRFSYEGLNSADRLTRPLLKQGGQWIETDWQTALEYVANGLSSIKRDHGADQIAALASPH
STLEELYLLGKLMRGIGSDNVDFRLRQSDFSAALKGAPWLGMPVADVSTLQRVLVIGSSLRKDHPLLASRLRQAGKKGAR
VAVLGAGGEDLLMPLAARIDVAPSGWTAALAGIARAVATAKGVAAPAGTEGFDGGDAARAAADALLSGERRAVFLGNEAV
RHPQFAALHALAQWIATEAGATLGFLTEAANTVGGYVAGALPKQGGANAQAMLESPRKAYVLLNTEPEFDAADPRKALAA
LAQAGTVVVLSPFRSEAAMQYADVILPVTPFTETAGTFVNCEGLPQSFNGVVRALGESRPAWKVLRVLGNLLDVAGFDYD
SAEAVRAEVLANPVAPQLSNATDAPIRVSAAAANGIERIADVPIYHADPIVRRAESLQLTAAARRAQQVALSADLFAGLG
IQSGDPVRVTQGEGSVVLPGVLENTLPANTVRVPAATPAAMSLGAMFGTVKVEKAVDLSAGQKAAATAGAA

Sequences:

>Translated_791_residues
MVELEIDGKKVEVAEGSLVMEAARKLGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTPGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGASESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANLVVQSKNQR
VMRVLPLENEDVNECWISDKDRFSYEGLNSADRLTRPLLKQGGQWIETDWQTALEYVANGLSSIKRDHGADQIAALASPH
STLEELYLLGKLMRGIGSDNVDFRLRQSDFSAALKGAPWLGMPVADVSTLQRVLVIGSSLRKDHPLLASRLRQAGKKGAR
VAVLGAGGEDLLMPLAARIDVAPSGWTAALAGIARAVATAKGVAAPAGTEGFDGGDAARAAADALLSGERRAVFLGNEAV
RHPQFAALHALAQWIATEAGATLGFLTEAANTVGGYVAGALPKQGGANAQAMLESPRKAYVLLNTEPEFDAADPRKALAA
LAQAGTVVVLSPFRSEAAMQYADVILPVTPFTETAGTFVNCEGLPQSFNGVVRALGESRPAWKVLRVLGNLLDVAGFDYD
SAEAVRAEVLANPVAPQLSNATDAPIRVSAAAANGIERIADVPIYHADPIVRRAESLQLTAAARRAQQVALSADLFAGLG
IQSGDPVRVTQGEGSVVLPGVLENTLPANTVRVPAATPAAMSLGAMFGTVKVEKAVDLSAGQKAAATAGAA
>Mature_791_residues
MVELEIDGKKVEVAEGSLVMEAARKLGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALPACATPVTPGMKVFTNSEKAV
KAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGASESRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANLVVQSKNQR
VMRVLPLENEDVNECWISDKDRFSYEGLNSADRLTRPLLKQGGQWIETDWQTALEYVANGLSSIKRDHGADQIAALASPH
STLEELYLLGKLMRGIGSDNVDFRLRQSDFSAALKGAPWLGMPVADVSTLQRVLVIGSSLRKDHPLLASRLRQAGKKGAR
VAVLGAGGEDLLMPLAARIDVAPSGWTAALAGIARAVATAKGVAAPAGTEGFDGGDAARAAADALLSGERRAVFLGNEAV
RHPQFAALHALAQWIATEAGATLGFLTEAANTVGGYVAGALPKQGGANAQAMLESPRKAYVLLNTEPEFDAADPRKALAA
LAQAGTVVVLSPFRSEAAMQYADVILPVTPFTETAGTFVNCEGLPQSFNGVVRALGESRPAWKVLRVLGNLLDVAGFDYD
SAEAVRAEVLANPVAPQLSNATDAPIRVSAAAANGIERIADVPIYHADPIVRRAESLQLTAAARRAQQVALSADLFAGLG
IQSGDPVRVTQGEGSVVLPGVLENTLPANTVRVPAATPAAMSLGAMFGTVKVEKAVDLSAGQKAAATAGAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=729, Percent_Identity=35.5281207133059, Blast_Score=399, Evalue=1e-111,
Organism=Escherichia coli, GI145693161, Length=714, Percent_Identity=28.2913165266106, Blast_Score=223, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17565758, Length=678, Percent_Identity=36.5781710914454, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI32566231, Length=619, Percent_Identity=37.6413570274636, Blast_Score=348, Evalue=8e-96,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=51.984126984127, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24640559, Length=676, Percent_Identity=35.7988165680473, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24640557, Length=676, Percent_Identity=35.7988165680473, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 83806; Mature: 83806

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELEIDGKKVEVAEGSLVMEAARKLGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALP
CEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVTPGMKVFTNSEKAVKAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGASE
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCH
SRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMLNRGEHSEITTF
HHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANLVVQSKNQR
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCC
VMRVLPLENEDVNECWISDKDRFSYEGLNSADRLTRPLLKQGGQWIETDWQTALEYVANG
EEEEECCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
LSSIKRDHGADQIAALASPHSTLEELYLLGKLMRGIGSDNVDFRLRQSDFSAALKGAPWL
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCC
GMPVADVSTLQRVLVIGSSLRKDHPLLASRLRQAGKKGARVAVLGAGGEDLLMPLAARID
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHEE
VAPSGWTAALAGIARAVATAKGVAAPAGTEGFDGGDAARAAADALLSGERRAVFLGNEAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHH
RHPQFAALHALAQWIATEAGATLGFLTEAANTVGGYVAGALPKQGGANAQAMLESPRKAY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEE
VLLNTEPEFDAADPRKALAALAQAGTVVVLSPFRSEAAMQYADVILPVTPFTETAGTFVN
EEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHEEEECCCCCCCCCCEEE
CEGLPQSFNGVVRALGESRPAWKVLRVLGNLLDVAGFDYDSAEAVRAEVLANPVAPQLSN
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
ATDAPIRVSAAAANGIERIADVPIYHADPIVRRAESLQLTAAARRAQQVALSADLFAGLG
CCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IQSGDPVRVTQGEGSVVLPGVLENTLPANTVRVPAATPAAMSLGAMFGTVKVEKAVDLSA
CCCCCCEEEECCCCCEEECHHHHCCCCCCEEECCCCCHHHHHHHHHHHHEEEEHHHCCCC
GQKAAATAGAA
CCHHHHCCCCC
>Mature Secondary Structure
MVELEIDGKKVEVAEGSLVMEAARKLGTYIPHFCYHRKLSIAANCRMCLVEVEKAPKALP
CEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVTPGMKVFTNSEKAVKAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGASE
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCH
SRYKEEKRVVFHKNVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMLNRGEHSEITTF
HHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGQTVDSELSGNMIDLCPVGALTSKPFRYSARTWELARRKSVSPHDGLGANLVVQSKNQR
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCC
VMRVLPLENEDVNECWISDKDRFSYEGLNSADRLTRPLLKQGGQWIETDWQTALEYVANG
EEEEECCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
LSSIKRDHGADQIAALASPHSTLEELYLLGKLMRGIGSDNVDFRLRQSDFSAALKGAPWL
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCC
GMPVADVSTLQRVLVIGSSLRKDHPLLASRLRQAGKKGARVAVLGAGGEDLLMPLAARID
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHEE
VAPSGWTAALAGIARAVATAKGVAAPAGTEGFDGGDAARAAADALLSGERRAVFLGNEAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHH
RHPQFAALHALAQWIATEAGATLGFLTEAANTVGGYVAGALPKQGGANAQAMLESPRKAY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEE
VLLNTEPEFDAADPRKALAALAQAGTVVVLSPFRSEAAMQYADVILPVTPFTETAGTFVN
EEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHEEEECCCCCCCCCCEEE
CEGLPQSFNGVVRALGESRPAWKVLRVLGNLLDVAGFDYDSAEAVRAEVLANPVAPQLSN
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
ATDAPIRVSAAAANGIERIADVPIYHADPIVRRAESLQLTAAARRAQQVALSADLFAGLG
CCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IQSGDPVRVTQGEGSVVLPGVLENTLPANTVRVPAATPAAMSLGAMFGTVKVEKAVDLSA
CCCCCCEEEECCCCCEEECHHHHCCCCCCEEECCCCCHHHHHHHHHHHHEEEEHHHCCCC
GQKAAATAGAA
CCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]