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The map label for this gene is yhfN [H]

Identifier: 73540609

GI number: 73540609

Start: 987886

End: 989169

Strand: Reverse

Name: yhfN [H]

Synonym: Reut_A0906

Alternate gene names: 73540609

Gene position: 989169-987886 (Counterclockwise)

Preceding gene: 73540612

Following gene: 73540608

Centisome position: 25.99

GC content: 64.56

Gene sequence:

>1284_bases
ATGGTCGCCGCTGCGTCCCCGACAAGGCTTTTGCCGATGTTCACGCTTATTTTCCTCGCCGCGCTGGTCGTCATGGTGCT
GACCAAGCTGTGGCTGGCGGCCCGCCAGGTCCGCTATGTTGGCCAGCACCGCAACGCCGTGCCGCCCCGCTTTGCCGATA
CCATCGCGCTGCCTTCGCACCAGAAGGCAGCCGATTACACCATCGCCCGAACGCGGCTGTCGATGCTCGAAGTGCTGGCC
GGCGCCGCCGTACTGATCGGCTTCACCATGCTCGGCGGCCTGCAGTGGCTGAACCAGTTCTGGCTCGACATGTTCGGTCC
CGGCTACGCGTACGGCGTGGCGCTGATCGCCAGCGTCGCGCTGATCGGCGGGCTGGTGGACCTGCCCTTCTCGCTGTACG
GCCAGTTCGGTATCGAAGAACGCTTCGGCTTCAACAAGATGACCTTCGGCCTGTGGCTCGCCGACATGGTCAAGATGCTG
CTGGTTGCGTGCGTGCTGGGACTGCCGCTGCTGCTCGCGGTGCTCTGGCTGATGGACCGCACCGGCAGCCTGTGGTGGGT
GTGGACATGGCTGGTATGGATGGCGTTCAACCTGTTGCTGCTGATCGTGTTCCCGACGTTCATCGCGCCGCTGTTCAACA
AGTTCGAACCGCTCACCGATGAGTCGCTGCGCCAGCGCATCGAGGCACTCATGAAGAAGTGCGGCTTCGCCAGCAAAGGC
CTGTTCGTGATGGATGGCAGCAAGCGCAGCGCGCATGGCAATGCCTATTTCACGGGTTTCGGCGCGGCCAAGCGCATCGT
GTTCTTCGACACGCTGCTCGGGCGCCTGTCCGGCGACGAGATCGAGGCCGTGCTGGCCCATGAGCTCGGCCACTTCAAGC
GCCGCCACGTGGCCAAGCGCATTGCCGTGACGTTCGCGCTGAGCCTGGTGTTCCTGGCATTGCTCGGCTGGCTTTCGACG
CGCACGTGGTTCTATACGGGGCTCGGCGTGGCGCCGAACCTTGGTGTCTCGAACAGCGCGCTGGCGCTGGTGCTGTTCTT
CCTGACGCTGCCGGTGTTCACGTTCCTGCTCGGGCCGTTGTCGAGCCAGTCGTCGCGCAAGCATGAGTTTGAAGCCGATG
CCTTTGCCGCCGACCAGACCAATGCGGGCCACCTGGTCTCGGCACTGGTCAAGCTGTACAAGGACAACGCCTCCACGCTG
ACCCCCGACCCGCTCTACAGCGCCTTCTACTACTCGCACCCGCCCGCCGCGCAGCGGATCGACCGGCTGCTGGCGCACGC
ATGA

Upstream 100 bases:

>100_bases
ACTTATAATTCTCGCATATCCGTCCGCCGTGGCAGCGCGCAGTGCACCTGTACCGCACATGCGCCGTCTCTGTGGATAAC
CTGCGCAGCGTCAGCCACAT

Downstream 100 bases:

>100_bases
GCCGCACCGGACGACACCGCAATGCCGGCGGTAATTCCGGCACAGGCAAAGCCGCCGCCGAAGGCGCCCTGGTCATCGCC
GCGCATGGCCGCCACTACGT

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MVAAASPTRLLPMFTLIFLAALVVMVLTKLWLAARQVRYVGQHRNAVPPRFADTIALPSHQKAADYTIARTRLSMLEVLA
GAAVLIGFTMLGGLQWLNQFWLDMFGPGYAYGVALIASVALIGGLVDLPFSLYGQFGIEERFGFNKMTFGLWLADMVKML
LVACVLGLPLLLAVLWLMDRTGSLWWVWTWLVWMAFNLLLLIVFPTFIAPLFNKFEPLTDESLRQRIEALMKKCGFASKG
LFVMDGSKRSAHGNAYFTGFGAAKRIVFFDTLLGRLSGDEIEAVLAHELGHFKRRHVAKRIAVTFALSLVFLALLGWLST
RTWFYTGLGVAPNLGVSNSALALVLFFLTLPVFTFLLGPLSSQSSRKHEFEADAFAADQTNAGHLVSALVKLYKDNASTL
TPDPLYSAFYYSHPPAAQRIDRLLAHA

Sequences:

>Translated_427_residues
MVAAASPTRLLPMFTLIFLAALVVMVLTKLWLAARQVRYVGQHRNAVPPRFADTIALPSHQKAADYTIARTRLSMLEVLA
GAAVLIGFTMLGGLQWLNQFWLDMFGPGYAYGVALIASVALIGGLVDLPFSLYGQFGIEERFGFNKMTFGLWLADMVKML
LVACVLGLPLLLAVLWLMDRTGSLWWVWTWLVWMAFNLLLLIVFPTFIAPLFNKFEPLTDESLRQRIEALMKKCGFASKG
LFVMDGSKRSAHGNAYFTGFGAAKRIVFFDTLLGRLSGDEIEAVLAHELGHFKRRHVAKRIAVTFALSLVFLALLGWLST
RTWFYTGLGVAPNLGVSNSALALVLFFLTLPVFTFLLGPLSSQSSRKHEFEADAFAADQTNAGHLVSALVKLYKDNASTL
TPDPLYSAFYYSHPPAAQRIDRLLAHA
>Mature_427_residues
MVAAASPTRLLPMFTLIFLAALVVMVLTKLWLAARQVRYVGQHRNAVPPRFADTIALPSHQKAADYTIARTRLSMLEVLA
GAAVLIGFTMLGGLQWLNQFWLDMFGPGYAYGVALIASVALIGGLVDLPFSLYGQFGIEERFGFNKMTFGLWLADMVKML
LVACVLGLPLLLAVLWLMDRTGSLWWVWTWLVWMAFNLLLLIVFPTFIAPLFNKFEPLTDESLRQRIEALMKKCGFASKG
LFVMDGSKRSAHGNAYFTGFGAAKRIVFFDTLLGRLSGDEIEAVLAHELGHFKRRHVAKRIAVTFALSLVFLALLGWLST
RTWFYTGLGVAPNLGVSNSALALVLFFLTLPVFTFLLGPLSSQSSRKHEFEADAFAADQTNAGHLVSALVKLYKDNASTL
TPDPLYSAFYYSHPPAAQRIDRLLAHA

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=466, Percent_Identity=31.7596566523605, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17505484, Length=424, Percent_Identity=32.0754716981132, Blast_Score=191, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6322577, Length=420, Percent_Identity=34.2857142857143, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI19922414, Length=427, Percent_Identity=32.0843091334895, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24654305, Length=249, Percent_Identity=31.3253012048193, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI78707252, Length=311, Percent_Identity=27.9742765273312, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI78707254, Length=311, Percent_Identity=27.9742765273312, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 47305; Mature: 47305

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCC
>Mature Secondary Structure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HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]