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The map label for this gene is mogA [H]

Identifier: 73540612

GI number: 73540612

Start: 990945

End: 991583

Strand: Reverse

Name: mogA [H]

Synonym: Reut_A0909

Alternate gene names: 73540612

Gene position: 991583-990945 (Counterclockwise)

Preceding gene: 73540613

Following gene: 73540609

Centisome position: 26.05

GC content: 66.51

Gene sequence:

>639_bases
ATGACGCAGACCACGCAACCGATCGCCCGCAACCACCCTGATGAACTCGTGGTGGCCTTCGTCTCGATTTCCGACCGCGC
TTCGGCCGGCACCTATCAGGACGAAGGCATCCCCGCCCTGCGCGAATGGTTCGGCCGCACGCTGACCTCGCCGTGGCAAG
GTGTAGAGCGGTTGATTCCGGACGAGCAGGCGCAGATCTCACGCACGCTGATCGATCTGGTCGATGTGTCCGGTTGCGAC
CTGGTCCTGACCACTGGCGGCACCGGCCCGGCGCGGCGCGACGTCACGCCCGAAGCAACGCTGGCCGTGGCCACCAAGGA
AATGCCGGGCTTCGGCGAGCAGATGCGCCAGGTGAGCCTGCACTTCGTGCCGACGGCGATCCTGTCGCGCCAGGTGGCCG
TGATCCGCGAAACGCCGAGCCGCGCCGCGCTGATCATCAACCTGCCGGGCCAGCCGCGCGCGATCCGCGAGACGCTGGAA
GGCCTGCGCGACGATGCGGGCAAATCGGTGGTGCAGGGAATTTTTGCTGCAGTGCCATATTGCATCGACCTGATCGGCGG
CCCATACATCGAGACCGACGAGAGTGTGGTCAAGGCCTGGCGGCCCAAGAACGCAATCCGCAGCAAGCCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCCGCGCTACTTCCGCGAGCTGTTCCAGGCCATCAAGGCCGCGCTGGATGAGAAGGACAGCGCCGCTGGCGAACAACCC
CCGACCCCGGAGCCCGAGGC

Downstream 100 bases:

>100_bases
GCGGCAAGTCGCTGGGGCTCAGCGCAGCCCCAGATAGAGCCCAATCGGCACGAACAGGACGGCGGCGATATTGCCGAGCA
GCACGATCGACGCCACCTGG

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTQTTQPIARNHPDELVVAFVSISDRASAGTYQDEGIPALREWFGRTLTSPWQGVERLIPDEQAQISRTLIDLVDVSGCD
LVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQVSLHFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLE
GLRDDAGKSVVQGIFAAVPYCIDLIGGPYIETDESVVKAWRPKNAIRSKPAA

Sequences:

>Translated_212_residues
MTQTTQPIARNHPDELVVAFVSISDRASAGTYQDEGIPALREWFGRTLTSPWQGVERLIPDEQAQISRTLIDLVDVSGCD
LVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQVSLHFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLE
GLRDDAGKSVVQGIFAAVPYCIDLIGGPYIETDESVVKAWRPKNAIRSKPAA
>Mature_211_residues
TQTTQPIARNHPDELVVAFVSISDRASAGTYQDEGIPALREWFGRTLTSPWQGVERLIPDEQAQISRTLIDLVDVSGCDL
VLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQVSLHFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEG
LRDDAGKSVVQGIFAAVPYCIDLIGGPYIETDESVVKAWRPKNAIRSKPAA

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=188, Percent_Identity=34.5744680851064, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI10880983, Length=188, Percent_Identity=34.5744680851064, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786190, Length=194, Percent_Identity=67.5257731958763, Blast_Score=266, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17564954, Length=148, Percent_Identity=35.8108108108108, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136978, Length=173, Percent_Identity=32.3699421965318, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24638841, Length=173, Percent_Identity=32.3699421965318, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 22983; Mature: 22852

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTTQPIARNHPDELVVAFVSISDRASAGTYQDEGIPALREWFGRTLTSPWQGVERLIP
CCCCCCCHHHCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCC
DEQAQISRTLIDLVDVSGCDLVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQVSL
CHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHH
HFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGLRDDAGKSVVQGIFAAVPY
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIDLIGGPYIETDESVVKAWRPKNAIRSKPAA
HHHHHCCCCCCCCHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure 
TQTTQPIARNHPDELVVAFVSISDRASAGTYQDEGIPALREWFGRTLTSPWQGVERLIP
CCCCCCHHHCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCC
DEQAQISRTLIDLVDVSGCDLVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQVSL
CHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHH
HFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGLRDDAGKSVVQGIFAAVPY
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIDLIGGPYIETDESVVKAWRPKNAIRSKPAA
HHHHHCCCCCCCCHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]