Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 73540597

GI number: 73540597

Start: 975638

End: 976318

Strand: Direct

Name: crp [C]

Synonym: Reut_A0894

Alternate gene names: 73540597

Gene position: 975638-976318 (Clockwise)

Preceding gene: 73540594

Following gene: 73540598

Centisome position: 25.63

GC content: 67.84

Gene sequence:

>681_bases
GTGAAAGCCGTGGATTCCGGCAAGGCGCTGCCGCGCAGCGTGATCACGACAGGGTGGCTGCGCAATGCGCCAGCCCGCGT
GCTCGATGCCGTGCAGAAGGCGGCGCGTCGCCAGCGCTTCGGTGACGGCGACATGATCTTTGCGCGCGGCGATCCGCCTA
CGTATTTCTGCATGGTGCTGGCGGGGCGCGTGCGCATGAGCCGCGTCAGCGCGAGCGGGCGCGAATCAGTCTATTCGGTG
ATCGGGCGCGGCCGGTGGTTCGGCGAGATCTCGCTGCTCGACGGCAAGCCGCGCACGCATGACGCGTTTGCCGTCGGCAG
CACTGAACTGCTGGTGCTGGGCCGCCGCGACTTCGACCGCATCTTGGTTGCGCATCCGGAAGGCATGCACCTGATCGTGC
AGCAGATGTGCGCACGGCTGCGCGTGGCGTTCGACCATACCGAACATGCGCAGCAGGCGCCTGTCGATGCGCGCATGGCT
GCGCGGCTGCTGGAACTGGCCGACCGCACCGACCACGTGGTGCGCGTGTCGGCCGAAGACCTCGGCGACATGGTCAACCG
TTCGCGCCAGACCGTGGCCAAGTATCTGCAGGCGTGGGAAGAGGCGGGCTGGATACGCCGCCACTACCGGCAGGTGGAAC
TGCTGCAGCCCGCGGCACTCAGGAAGCTGGCGACCGGTTGA

Upstream 100 bases:

>100_bases
TGTGTTCTGTATCGTGAGTGCGGTGGCATTCTGCGCCCGCGTGCCTGCGCAAGTCTGTTAAGTATTGGACAATCTCGCTT
TGGCCAGCGGGAGGGGTGAT

Downstream 100 bases:

>100_bases
GCGGGGTGCGCCGCGTGGTACATTCGCCGATGATGTAAACACCGCCCTATACAAGTCCAGCGGGCGCCGCGGCAGGATTG
CCGGCGGCGCCAGCCTCAAC

Product: cyclic nucleotide-binding

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Regulatory Protein; Catabolite Gene Activator; Cyclic AMP Receptor Protein; CRP Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Transcription Regulator Protein; Transcriptional Regulator Anr; CRP Protein; Transcription Regulator Crp Family; Transcriptional Regulatory Protein; Cyclic-Nucleotide-Gated Cation Channel; Transcriptional Regulator CRP-Family; Crp-Like Transcriptional Regulator; GntR Family Transcriptional Regulator; Transcriptional Regulatory Protein Crp Family; Transcriptional Regulator Crp; Crp Family Regulatory Protein; DNR Protein; Transcription Regulator; CAMP-Bindin Transcriptional Regulator; Global Nitrogen Regulator NtcA; Transcriptional Regulator Crp Family; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKAVDSGKALPRSVITTGWLRNAPARVLDAVQKAARRQRFGDGDMIFARGDPPTYFCMVLAGRVRMSRVSASGRESVYSV
IGRGRWFGEISLLDGKPRTHDAFAVGSTELLVLGRRDFDRILVAHPEGMHLIVQQMCARLRVAFDHTEHAQQAPVDARMA
ARLLELADRTDHVVRVSAEDLGDMVNRSRQTVAKYLQAWEEAGWIRRHYRQVELLQPAALRKLATG

Sequences:

>Translated_226_residues
MKAVDSGKALPRSVITTGWLRNAPARVLDAVQKAARRQRFGDGDMIFARGDPPTYFCMVLAGRVRMSRVSASGRESVYSV
IGRGRWFGEISLLDGKPRTHDAFAVGSTELLVLGRRDFDRILVAHPEGMHLIVQQMCARLRVAFDHTEHAQQAPVDARMA
ARLLELADRTDHVVRVSAEDLGDMVNRSRQTVAKYLQAWEEAGWIRRHYRQVELLQPAALRKLATG
>Mature_226_residues
MKAVDSGKALPRSVITTGWLRNAPARVLDAVQKAARRQRFGDGDMIFARGDPPTYFCMVLAGRVRMSRVSASGRESVYSV
IGRGRWFGEISLLDGKPRTHDAFAVGSTELLVLGRRDFDRILVAHPEGMHLIVQQMCARLRVAFDHTEHAQQAPVDARMA
ARLLELADRTDHVVRVSAEDLGDMVNRSRQTVAKYLQAWEEAGWIRRHYRQVELLQPAALRKLATG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25343; Mature: 25343

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVDSGKALPRSVITTGWLRNAPARVLDAVQKAARRQRFGDGDMIFARGDPPTYFCMVL
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
AGRVRMSRVSASGRESVYSVIGRGRWFGEISLLDGKPRTHDAFAVGSTELLVLGRRDFDR
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCEEEEECCCCCCE
ILVAHPEGMHLIVQQMCARLRVAFDHTEHAQQAPVDARMAARLLELADRTDHVVRVSAED
EEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECHHH
LGDMVNRSRQTVAKYLQAWEEAGWIRRHYRQVELLQPAALRKLATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MKAVDSGKALPRSVITTGWLRNAPARVLDAVQKAARRQRFGDGDMIFARGDPPTYFCMVL
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
AGRVRMSRVSASGRESVYSVIGRGRWFGEISLLDGKPRTHDAFAVGSTELLVLGRRDFDR
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCEEEEECCCCCCE
ILVAHPEGMHLIVQQMCARLRVAFDHTEHAQQAPVDARMAARLLELADRTDHVVRVSAED
EEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECHHH
LGDMVNRSRQTVAKYLQAWEEAGWIRRHYRQVELLQPAALRKLATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA