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The map label for this gene is 73540560

Identifier: 73540560

GI number: 73540560

Start: 928660

End: 929433

Strand: Direct

Name: 73540560

Synonym: Reut_A0857

Alternate gene names: NA

Gene position: 928660-929433 (Clockwise)

Preceding gene: 73540559

Following gene: 73540561

Centisome position: 24.4

GC content: 67.05

Gene sequence:

>774_bases
ATGTCTTTTACCTTGCAGCCGGCGCGTGCCGCCGGAGCACCCAGCCCCGTCACGCCGGAAGAGCAGCGCGTCCGCGTCGA
CCTGGCAGCCGCCTACCGGCTGTCGGCGCTCCAGGGCTGGGATGACCTGATCTACACCCATATCTCGGCCACGGTTCCTG
GCGAGCCGGATCACTTCCTGATCAACCCGTTCGGCTTTGCCTTCGAGGAAATCCGGGCATCGGACCTCGTCAAGATCAAT
GGCCGCGGCGAGGTGGTCGGCGAGACCGTCCATCCGGTCAATGTGACCGGCTTCGCGCTGCACGGCGCGGTGCACGCGGC
ACGCGCCGATGCGATGTGCGTCATGCACCTGCACAACACCGCCGGCATCGCGGTGTCGGCACAGGCCGAAGGCCTCCTGC
CGCTGTCGCAGCACGCGATGCGTTTCCACTGTCGCATGGCTTACCACGACTACGAAGGCCTCGCGTTCACGCCGGCCGAA
GGCGCGCGGCTGACGGCATCGCTCGGCCAGCAGCAGGCCATGCTCTTGCGCAATCACGGCACGCTCACCGTCGGTCGTAC
GGTTGCCGAAGCCTATGTGCTGATGGCGACGCTGATCAAGGCATGCGAGGTCCAGATCGGCGCGCAGGCAGGCGGCCGGC
TCGTGCGACCCGCGCCCGGCGTGGCGGAAAAGGCGTCCGAGCAGCTCTACGACAACGGCGCCATAGAAGGCGCGCTGGAG
TGGCCGGCGCTGCTGCGCAAACTCGATAGAATCGATGCCTCGTTCCGGGACTGA

Upstream 100 bases:

>100_bases
TGCGCTACAGTAACGCCTTCGCCGCCCTTTTGCGGACTCCAGACTCAGGAAGCCGGGACCAACACCGGCACCAGACACCG
GGCGGCGCAGGAGCGACCCC

Downstream 100 bases:

>100_bases
TTGCCCGCGACAGACAGACGAACAAACGAACACCCAAAGACAACGCAAGGAGCCAGGAATGCCGACGTTTCACGTAGAGA
TGTTTGAAGGCCGCACCATC

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSFTLQPARAAGAPSPVTPEEQRVRVDLAAAYRLSALQGWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKIN
GRGEVVGETVHPVNVTGFALHGAVHAARADAMCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHCRMAYHDYEGLAFTPAE
GARLTASLGQQQAMLLRNHGTLTVGRTVAEAYVLMATLIKACEVQIGAQAGGRLVRPAPGVAEKASEQLYDNGAIEGALE
WPALLRKLDRIDASFRD

Sequences:

>Translated_257_residues
MSFTLQPARAAGAPSPVTPEEQRVRVDLAAAYRLSALQGWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKIN
GRGEVVGETVHPVNVTGFALHGAVHAARADAMCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHCRMAYHDYEGLAFTPAE
GARLTASLGQQQAMLLRNHGTLTVGRTVAEAYVLMATLIKACEVQIGAQAGGRLVRPAPGVAEKASEQLYDNGAIEGALE
WPALLRKLDRIDASFRD
>Mature_256_residues
SFTLQPARAAGAPSPVTPEEQRVRVDLAAAYRLSALQGWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKING
RGEVVGETVHPVNVTGFALHGAVHAARADAMCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHCRMAYHDYEGLAFTPAEG
ARLTASLGQQQAMLLRNHGTLTVGRTVAEAYVLMATLIKACEVQIGAQAGGRLVRPAPGVAEKASEQLYDNGAIEGALEW
PALLRKLDRIDASFRD

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=197, Percent_Identity=46.7005076142132, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI29826319, Length=197, Percent_Identity=46.7005076142132, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI29826321, Length=197, Percent_Identity=46.7005076142132, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI29826323, Length=197, Percent_Identity=46.7005076142132, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI297307158, Length=197, Percent_Identity=43.1472081218274, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI9257192, Length=197, Percent_Identity=43.1472081218274, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI9257190, Length=197, Percent_Identity=43.1472081218274, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI89276787, Length=197, Percent_Identity=43.1472081218274, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI297307160, Length=197, Percent_Identity=43.1472081218274, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI9943848, Length=194, Percent_Identity=40.7216494845361, Blast_Score=140, Evalue=9e-34,
Organism=Homo sapiens, GI9951927, Length=194, Percent_Identity=40.7216494845361, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI62912453, Length=194, Percent_Identity=40.7216494845361, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI115533216, Length=251, Percent_Identity=39.4422310756972, Blast_Score=163, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI115533218, Length=251, Percent_Identity=39.4422310756972, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71989550, Length=238, Percent_Identity=33.6134453781513, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71989560, Length=242, Percent_Identity=33.4710743801653, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71989544, Length=238, Percent_Identity=33.6134453781513, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71989541, Length=238, Percent_Identity=33.6134453781513, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71989555, Length=242, Percent_Identity=33.4710743801653, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281363755, Length=189, Percent_Identity=37.5661375661376, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363751, Length=189, Percent_Identity=37.5661375661376, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655690, Length=189, Percent_Identity=37.5661375661376, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655685, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363761, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363759, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363753, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363763, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281363757, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136738, Length=189, Percent_Identity=37.5661375661376, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 27599; Mature: 27468

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTLQPARAAGAPSPVTPEEQRVRVDLAAAYRLSALQGWDDLIYTHISATVPGEPDHFL
CCCCCCCHHHCCCCCCCCCCHHEEEEEHHHHHHHHHHCCHHHHHEEEEEEECCCCCCEEE
INPFGFAFEEIRASDLVKINGRGEVVGETVHPVNVTGFALHGAVHAARADAMCVMHLHNT
ECCHHHHHHHHCCCCEEEECCCCCEEECEECCCEEEEEEHHHHHHHHHCCCEEEEEEECC
AGIAVSAQAEGLLPLSQHAMRFHCRMAYHDYEGLAFTPAEGARLTASLGQQQAMLLRNHG
CCEEEECCCCCCCCHHHHHHHHHEEEEEECCCCEEECCCCCCEEEHHHCHHHHHHHHCCC
TLTVGRTVAEAYVLMATLIKACEVQIGAQAGGRLVRPAPGVAEKASEQLYDNGAIEGALE
CEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHH
WPALLRKLDRIDASFRD
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SFTLQPARAAGAPSPVTPEEQRVRVDLAAAYRLSALQGWDDLIYTHISATVPGEPDHFL
CCCCCCHHHCCCCCCCCCCHHEEEEEHHHHHHHHHHCCHHHHHEEEEEEECCCCCCEEE
INPFGFAFEEIRASDLVKINGRGEVVGETVHPVNVTGFALHGAVHAARADAMCVMHLHNT
ECCHHHHHHHHCCCCEEEECCCCCEEECEECCCEEEEEEHHHHHHHHHCCCEEEEEEECC
AGIAVSAQAEGLLPLSQHAMRFHCRMAYHDYEGLAFTPAEGARLTASLGQQQAMLLRNHG
CCEEEECCCCCCCCHHHHHHHHHEEEEEECCCCEEECCCCCCEEEHHHCHHHHHHHHCCC
TLTVGRTVAEAYVLMATLIKACEVQIGAQAGGRLVRPAPGVAEKASEQLYDNGAIEGALE
CEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHH
WPALLRKLDRIDASFRD
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]