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The map label for this gene is pcaR [H]

Identifier: 73540509

GI number: 73540509

Start: 876315

End: 877118

Strand: Direct

Name: pcaR [H]

Synonym: Reut_A0806

Alternate gene names: 73540509

Gene position: 876315-877118 (Clockwise)

Preceding gene: 73540504

Following gene: 73540513

Centisome position: 23.02

GC content: 66.29

Gene sequence:

>804_bases
TTGAGCAGCCTTTCTCCAGACGCCACTTCCGCCGCCTCAGTGCGCGAAAGCGATCCCAATTTCGTCACGGCACTGGCCCG
CGGCCTGGAGTTGCTACGTTGTTTCCGCACCGGCGAGGCTATGCTCGGCAACCAGGATTTCGTGCGCCGTACAGGCTTCC
CCAAGGCTACCGTCAGCCGTCTGGCCGGGACGCTCGTGCAGCTTGGCTATCTGCGCTATGACGATAGCCTCGGAAAATAC
GCGCTCGATGCGGGCGTGCTGGCGCTAGGCTACGCCTATCTATCCGCTTCTGACGTGGTGGCGCTGGCCCGGCCGCATAT
GCTCGCGTTCGCGCAGTCCTACGGCGTGTCGGTGTCGCTCGGCAAGCGCGAGCGCATGGAAGTGACCTACCTGGAATCGA
TCCGTAACGACGCGGGTGTGATGCTGGGGCTGGGCGTGGGATCGCGGCTGTCGCTGGTGTCGAGCTCGATGGGGCGCGCC
TATCTGGCGGCGCTGCCGGCGGCGCGGCGGGAACGCGTGCTGGCCGAGTTCAGCCAGGCTTTTCCGGAGCAATGGAAGCA
GCAGGAAGCGCCAACGCGTGCGGCGCTTGAAGAGGCGGAACGGCGCGGCTATGCCTCGTCGTTCCGGGACTGGCACCCGG
CTATCCATGCCTGTGCGGTGGCATTCCGGCCGGTAGGGGAGAAGGAGCCGCACATGCTCAGCTGCAGCGCCTCGTACGGG
ACCGTCGAAGAGTCCGTGTTCCACGAAACCCTTGCACCGGCCCTGAAGGCGCTGGCCGCACGCCTGTCGGATCCGGCCGG
CTGA

Upstream 100 bases:

>100_bases
CGTTGGATTAGTATATCGCAATGCGTTCGCCATGCAAGCGGGATGACCACGGTGTGTTCGATTGTCGCGCGTGGCGCCCG
ACCGCCCACAGGAGCCAGCC

Downstream 100 bases:

>100_bases
CGCCGGCCTTGCTGGCTCGCTGCCGCCTTACAGGTCCGTACGCAGTTTCCACAGTTCCGGGAACAGCACCACGTCGAGCA
TCTTGCGCAGATAGCTGACG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSSLSPDATSAASVRESDPNFVTALARGLELLRCFRTGEAMLGNQDFVRRTGFPKATVSRLAGTLVQLGYLRYDDSLGKY
ALDAGVLALGYAYLSASDVVALARPHMLAFAQSYGVSVSLGKRERMEVTYLESIRNDAGVMLGLGVGSRLSLVSSSMGRA
YLAALPAARRERVLAEFSQAFPEQWKQQEAPTRAALEEAERRGYASSFRDWHPAIHACAVAFRPVGEKEPHMLSCSASYG
TVEESVFHETLAPALKALAARLSDPAG

Sequences:

>Translated_267_residues
MSSLSPDATSAASVRESDPNFVTALARGLELLRCFRTGEAMLGNQDFVRRTGFPKATVSRLAGTLVQLGYLRYDDSLGKY
ALDAGVLALGYAYLSASDVVALARPHMLAFAQSYGVSVSLGKRERMEVTYLESIRNDAGVMLGLGVGSRLSLVSSSMGRA
YLAALPAARRERVLAEFSQAFPEQWKQQEAPTRAALEEAERRGYASSFRDWHPAIHACAVAFRPVGEKEPHMLSCSASYG
TVEESVFHETLAPALKALAARLSDPAG
>Mature_266_residues
SSLSPDATSAASVRESDPNFVTALARGLELLRCFRTGEAMLGNQDFVRRTGFPKATVSRLAGTLVQLGYLRYDDSLGKYA
LDAGVLALGYAYLSASDVVALARPHMLAFAQSYGVSVSLGKRERMEVTYLESIRNDAGVMLGLGVGSRLSLVSSSMGRAY
LAALPAARRERVLAEFSQAFPEQWKQQEAPTRAALEEAERRGYASSFRDWHPAIHACAVAFRPVGEKEPHMLSCSASYGT
VEESVFHETLAPALKALAARLSDPAG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=199, Percent_Identity=24.1206030150754, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28797; Mature: 28666

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSPDATSAASVRESDPNFVTALARGLELLRCFRTGEAMLGNQDFVRRTGFPKATVSR
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCHHHHHH
LAGTLVQLGYLRYDDSLGKYALDAGVLALGYAYLSASDVVALARPHMLAFAQSYGVSVSL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GKRERMEVTYLESIRNDAGVMLGLGVGSRLSLVSSSMGRAYLAALPAARRERVLAEFSQA
CCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FPEQWKQQEAPTRAALEEAERRGYASSFRDWHPAIHACAVAFRPVGEKEPHMLSCSASYG
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
TVEESVFHETLAPALKALAARLSDPAG
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSLSPDATSAASVRESDPNFVTALARGLELLRCFRTGEAMLGNQDFVRRTGFPKATVSR
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCHHHHHH
LAGTLVQLGYLRYDDSLGKYALDAGVLALGYAYLSASDVVALARPHMLAFAQSYGVSVSL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GKRERMEVTYLESIRNDAGVMLGLGVGSRLSLVSSSMGRAYLAALPAARRERVLAEFSQA
CCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FPEQWKQQEAPTRAALEEAERRGYASSFRDWHPAIHACAVAFRPVGEKEPHMLSCSASYG
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
TVEESVFHETLAPALKALAARLSDPAG
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]