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The map label for this gene is lrp [H]

Identifier: 73540513

GI number: 73540513

Start: 880147

End: 880635

Strand: Direct

Name: lrp [H]

Synonym: Reut_A0810

Alternate gene names: 73540513

Gene position: 880147-880635 (Clockwise)

Preceding gene: 73540509

Following gene: 73540515

Centisome position: 23.12

GC content: 63.6

Gene sequence:

>489_bases
ATGACTCTTGATCCTATTGATTTGCGCATCCTGGAGTGCCTCCAGGAGCACGGCCGCATCAGCAATCAGGACCTGGCCGA
TCGCGTGGCGCTGTCGCCGTCGGCGTGCCTGCGGCGCGTGCGGCTGCTGGAGGAATCAGGCGTCATCGGCGGTTACCGCG
CGTGGTTCGACGCCGAGCGGCTGGGGCTGGAACTGGAAGCGATCGTGCAGGTGTCGATGCGGCACGACGTGGAGGGCTGG
CACGACACGTTTATCGCGGCCGTGCAGGCGTGGCCGGAGGTGCTGTCGGCTTACATCATCACTGGCGACAGCAACTACAT
CCTGCGCGTGCAGGCGCGCAATCTGAAGCACTACTCGGATTTCATCGTGAACCGGCTGTACCGTACACCGGGCGTGATGG
ATATCCGCTCCAACATCGTGCTGCAGCGGATCAAGACGGATAGTTCGCCGCTGGCCGTGCTGAAGGCGGCCGATCCGGCA
GGAACCTGA

Upstream 100 bases:

>100_bases
AGTCAAAAAAACCGGCAAGAGGCTTGCGAAATCCACTGCTGAATGCCGGTTATTTCGCATAAAATTCGAAAATCTACTAG
ATTTAAGCGTAAATATTCGA

Downstream 100 bases:

>100_bases
AGATGGGGCGGGGAGGCGGGCGGCGGTCAGCCTTCCAGCGGCGTCGTGGTCGAGAAGATGCCGTTTTGGAAAATCAGCGG
CGGCTCGTGGCTTTCGAGCA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTLDPIDLRILECLQEHGRISNQDLADRVALSPSACLRRVRLLEESGVIGGYRAWFDAERLGLELEAIVQVSMRHDVEGW
HDTFIAAVQAWPEVLSAYIITGDSNYILRVQARNLKHYSDFIVNRLYRTPGVMDIRSNIVLQRIKTDSSPLAVLKAADPA
GT

Sequences:

>Translated_162_residues
MTLDPIDLRILECLQEHGRISNQDLADRVALSPSACLRRVRLLEESGVIGGYRAWFDAERLGLELEAIVQVSMRHDVEGW
HDTFIAAVQAWPEVLSAYIITGDSNYILRVQARNLKHYSDFIVNRLYRTPGVMDIRSNIVLQRIKTDSSPLAVLKAADPA
GT
>Mature_161_residues
TLDPIDLRILECLQEHGRISNQDLADRVALSPSACLRRVRLLEESGVIGGYRAWFDAERLGLELEAIVQVSMRHDVEGWH
DTFIAAVQAWPEVLSAYIITGDSNYILRVQARNLKHYSDFIVNRLYRTPGVMDIRSNIVLQRIKTDSSPLAVLKAADPAG
T

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=37.0629370629371, Blast_Score=103, Evalue=5e-24,
Organism=Escherichia coli, GI87081742, Length=147, Percent_Identity=34.0136054421769, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18229; Mature: 18098

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDPIDLRILECLQEHGRISNQDLADRVALSPSACLRRVRLLEESGVIGGYRAWFDAER
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LGLELEAIVQVSMRHDVEGWHDTFIAAVQAWPEVLSAYIITGDSNYILRVQARNLKHYSD
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCHHHHH
FIVNRLYRTPGVMDIRSNIVLQRIKTDSSPLAVLKAADPAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TLDPIDLRILECLQEHGRISNQDLADRVALSPSACLRRVRLLEESGVIGGYRAWFDAER
CCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LGLELEAIVQVSMRHDVEGWHDTFIAAVQAWPEVLSAYIITGDSNYILRVQARNLKHYSD
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCHHHHH
FIVNRLYRTPGVMDIRSNIVLQRIKTDSSPLAVLKAADPAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]