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The map label for this gene is minC [H]

Identifier: 73539770

GI number: 73539770

Start: 78024

End: 78860

Strand: Reverse

Name: minC [H]

Synonym: Reut_A0064

Alternate gene names: 73539770

Gene position: 78860-78024 (Counterclockwise)

Preceding gene: 73539777

Following gene: 73539769

Centisome position: 2.07

GC content: 66.79

Gene sequence:

>837_bases
ATGTGGCATTTCCACGGTCACCCGGCTATGTCACAGAAGAAATCGCCACGCTTCGAGCTGCGCAGTGGCAATGTAGACGC
CCTCCTTCTCGCCCTCCAGACCGCCGACATGGCTGCACTGCGGGACGACCTGCTCTCCCGGTTCGAAGCCACTCCCGATT
TCTTCTCCAATGACGTGATCGCGCTGGACCTGCGTGCGCTTGAAAGTGATGACGAGGTCTCGCTCGACGCGGTGATCGGC
ACGCTCGCGACGCTGAAGGCCCGTGCAATCGGCGTGGTCGCGCGGCCCGCGCAGCATGAGTGGGCCCAGCGCTTCGGCCT
GCCGCTGCTCGACAGCCAGAGCCGCCGCGGCCTGCGCGACGCGGCCGAAGCCGCCGAGGCCGCCGAACGTGCAGAACGCG
CCGCAGCCGAGGCCGCCGCTGAACAGTCCGCGCGCGACGAAGCCGCCCGCGCTGCTGCCCAGTCCGCCACCGAAGCCGCC
GTCAAGGCCGCCATCCAGCAAGCCCAGACCCTCCTGATCGACAAGCCGCTGCGCTCGGGCCAGCAGGTCTACGCGCAGGG
CGACGTGGTCATCATGGATGTGGTCAGCTACGGCGCCGAGGTGATCGCTGAAGGCAATATCCACGTCTATGCCCCGCTGC
GCGGCCGAGCGCTGGCGGGCGTCAAGGGCAATACCAGCGCGCGCATCTTCAGCACGTGCATGGAGCCCGAACTGATTTCC
ATTGCCGGCATCTACCGCACGGCCGAGCAGACCCTGCCGGCCGACGTGCTTGGCAAGTCCGCCCAGGTTCGCCTGGCCGA
TGAAAAGCTGATCTTGGAAGCGATCCGGATGAAATGA

Upstream 100 bases:

>100_bases
CTGTCGCAGGCACCACTTGGACACGTCAGATGGATTGCGTGCAGCACCTGAGGACAAAGTCCACCCATTTGTTACAGTTC
GCACCGAAGACGCAGTTAGA

Downstream 100 bases:

>100_bases
TCCGGCGGCGCCCAGCCACGAACTGAATCACTGCAGCGCAAGCTTCAACCTAATTACGGACCAAAGAGCCATGGCAAAAA
TCATCGTTGTGACCTCCGGC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MWHFHGHPAMSQKKSPRFELRSGNVDALLLALQTADMAALRDDLLSRFEATPDFFSNDVIALDLRALESDDEVSLDAVIG
TLATLKARAIGVVARPAQHEWAQRFGLPLLDSQSRRGLRDAAEAAEAAERAERAAAEAAAEQSARDEAARAAAQSATEAA
VKAAIQQAQTLLIDKPLRSGQQVYAQGDVVIMDVVSYGAEVIAEGNIHVYAPLRGRALAGVKGNTSARIFSTCMEPELIS
IAGIYRTAEQTLPADVLGKSAQVRLADEKLILEAIRMK

Sequences:

>Translated_278_residues
MWHFHGHPAMSQKKSPRFELRSGNVDALLLALQTADMAALRDDLLSRFEATPDFFSNDVIALDLRALESDDEVSLDAVIG
TLATLKARAIGVVARPAQHEWAQRFGLPLLDSQSRRGLRDAAEAAEAAERAERAAAEAAAEQSARDEAARAAAQSATEAA
VKAAIQQAQTLLIDKPLRSGQQVYAQGDVVIMDVVSYGAEVIAEGNIHVYAPLRGRALAGVKGNTSARIFSTCMEPELIS
IAGIYRTAEQTLPADVLGKSAQVRLADEKLILEAIRMK
>Mature_278_residues
MWHFHGHPAMSQKKSPRFELRSGNVDALLLALQTADMAALRDDLLSRFEATPDFFSNDVIALDLRALESDDEVSLDAVIG
TLATLKARAIGVVARPAQHEWAQRFGLPLLDSQSRRGLRDAAEAAEAAERAERAAAEAAAEQSARDEAARAAAQSATEAA
VKAAIQQAQTLLIDKPLRSGQQVYAQGDVVIMDVVSYGAEVIAEGNIHVYAPLRGRALAGVKGNTSARIFSTCMEPELIS
IAGIYRTAEQTLPADVLGKSAQVRLADEKLILEAIRMK

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=262, Percent_Identity=32.4427480916031, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 29882; Mature: 29882

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWHFHGHPAMSQKKSPRFELRSGNVDALLLALQTADMAALRDDLLSRFEATPDFFSNDVI
CCCCCCCCCCCCCCCCCEEECCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEE
ALDLRALESDDEVSLDAVIGTLATLKARAIGVVARPAQHEWAQRFGLPLLDSQSRRGLRD
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCCCCCCCCCHHH
AAEAAEAAERAERAAAEAAAEQSARDEAARAAAQSATEAAVKAAIQQAQTLLIDKPLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QQVYAQGDVVIMDVVSYGAEVIAEGNIHVYAPLRGRALAGVKGNTSARIFSTCMEPELIS
CEEEECCCEEEEHHHHHCHHEEECCCEEEEECCCCCEEECCCCCCCHHHHHHHCCCCHHH
IAGIYRTAEQTLPADVLGKSAQVRLADEKLILEAIRMK
HHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MWHFHGHPAMSQKKSPRFELRSGNVDALLLALQTADMAALRDDLLSRFEATPDFFSNDVI
CCCCCCCCCCCCCCCCCEEECCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEE
ALDLRALESDDEVSLDAVIGTLATLKARAIGVVARPAQHEWAQRFGLPLLDSQSRRGLRD
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCCCCCCCCCHHH
AAEAAEAAERAERAAAEAAAEQSARDEAARAAAQSATEAAVKAAIQQAQTLLIDKPLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QQVYAQGDVVIMDVVSYGAEVIAEGNIHVYAPLRGRALAGVKGNTSARIFSTCMEPELIS
CEEEECCCEEEEHHHHHCHHEEECCCEEEEECCCCCEEECCCCCCCHHHHHHHCCCCHHH
IAGIYRTAEQTLPADVLGKSAQVRLADEKLILEAIRMK
HHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA