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The map label for this gene is gudP [H]

Identifier: 73539754

GI number: 73539754

Start: 62310

End: 63608

Strand: Reverse

Name: gudP [H]

Synonym: Reut_A0048

Alternate gene names: 73539754

Gene position: 63608-62310 (Counterclockwise)

Preceding gene: 73539758

Following gene: 73539753

Centisome position: 1.67

GC content: 64.74

Gene sequence:

>1299_bases
ATGCAAACGACAAGCCAAGCCGGCACCCTCACGGCCACGCGCAGCAGCGTGCGCTGGAAAATCTTCCTGATGATGCTGAT
GCTCGTCGCGATCAACTACATCGATCGCGCCTCGCTGTCGGTGGCCATGCCACTGATCGCCAAGGAATTCGACCTCAGCC
CCGCCATGCAGGGCCTGATCCTCAGCTCCTTCTTCTGGACCTACGCGTTCATGCAGATCCCGGGCGGGATGCTGGCCGAC
AAGTACAAGCCGCGCATCGTGATCGCCTGCGCCACCGTGTTCTGGGGCTTCTTCCAGGCGATCGCGGCGGTCTGCACCAA
CGCCACCTCGCTGCTGCTGACCCGGCTCGGGCTGGGCGCGGCAGAAGCGCCGATCTACCCGGCCGGCGGCAAGCTCAACG
CCATCTGGATGACGCAGAACGAACGCGGCCGCGGCGCCACGCTGCTTGACGGCGGCGCACCGCTGGGCGCGGCGCTCGGC
TCGCTCATCATCGCCGGGCTGATCAGCGAACTCGGCTCCTGGCGCATGTCGTTCGTGGTCGCTGGCGTCGGCACCGTGCT
GGCCGGCTTCGTAGCCTGGTGGTACATCCGCAATTCGCCGCGCGAACACAGCGGCGTCAATGAACTGGAAGCGCGCCACA
TCGAGGAAGCGCATGCCCGCGAGCACAGCGCCGAGCCGACCAACCTGTCCGGCCGTTCGCTCGACTTCTTCAAGTACCGC
TCGGTGTGGTGCATGGCCATCAGCTGGATGTGCTTTAACGCCGTCTTCTACGGTCTGCTGACCTGGATGCCGACTTACCT
GAGCAAGGCACGCGGCTTTGACCTCAAGACGATGGGCGGCGCGAGCTTCCTGATCTTCATGAGCGGCTTCGTCGGCGAAC
TCGTCGGCGGCTGGATAGCCGACAAGTGGAAAGAAGCCGGCGGCCGTCCCAATGTGGTGATGCGCACGCTGTTCGGCATT
GCAGCTGTGGTCGCCACTGTGTCGATCTTCTCGGTGGCCTACGTCACGGACGCCGTGGCCGTGGTGGCGCTGCTGTCCTC
CACCCTGTTCTTCCTGCGCTGGTGCGGCCTGTTCTGGTCGGTGCCGTCGATGCTCGGCACGCGCAACAAGATCGGCTTCC
TGGGCGGCGTGATGAACCTGGGCGGCAACATCGCCGGCATCAGCGTGCCAATCATCGTCGGCCTGATCGTGCAAGCCACG
GGTTCCTACTTCCTGGCCCTGATGTTCTTCGCCGCCTGCGGCGTCGGCCTGCTGTTCGCGTCGACCAACATCGACTACGA
GACCAAGATCCCGGTCTGA

Upstream 100 bases:

>100_bases
TTGTAATTACAGATTACGTATCCTATACTCCGGCCAGTTGCGCGACACCTACTACAAACGCCTCAACCGAAGGACCTACG
GAGCAAGGAGACACCCCGTC

Downstream 100 bases:

>100_bases
CGACCTTCCCCCAGCAACGCTGTATCCGCCGCGCCGGTCCGTCCGACGGTCCACGCGGCGGTGGAGGAGACACACCATGA
CCCGCATTTCCCGCCTGCTG

Product: major facilitator transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MQTTSQAGTLTATRSSVRWKIFLMMLMLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAFMQIPGGMLAD
KYKPRIVIACATVFWGFFQAIAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTQNERGRGATLLDGGAPLGAALG
SLIIAGLISELGSWRMSFVVAGVGTVLAGFVAWWYIRNSPREHSGVNELEARHIEEAHAREHSAEPTNLSGRSLDFFKYR
SVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKTMGGASFLIFMSGFVGELVGGWIADKWKEAGGRPNVVMRTLFGI
AAVVATVSIFSVAYVTDAVAVVALLSSTLFFLRWCGLFWSVPSMLGTRNKIGFLGGVMNLGGNIAGISVPIIVGLIVQAT
GSYFLALMFFAACGVGLLFASTNIDYETKIPV

Sequences:

>Translated_432_residues
MQTTSQAGTLTATRSSVRWKIFLMMLMLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAFMQIPGGMLAD
KYKPRIVIACATVFWGFFQAIAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTQNERGRGATLLDGGAPLGAALG
SLIIAGLISELGSWRMSFVVAGVGTVLAGFVAWWYIRNSPREHSGVNELEARHIEEAHAREHSAEPTNLSGRSLDFFKYR
SVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKTMGGASFLIFMSGFVGELVGGWIADKWKEAGGRPNVVMRTLFGI
AAVVATVSIFSVAYVTDAVAVVALLSSTLFFLRWCGLFWSVPSMLGTRNKIGFLGGVMNLGGNIAGISVPIIVGLIVQAT
GSYFLALMFFAACGVGLLFASTNIDYETKIPV
>Mature_432_residues
MQTTSQAGTLTATRSSVRWKIFLMMLMLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAFMQIPGGMLAD
KYKPRIVIACATVFWGFFQAIAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTQNERGRGATLLDGGAPLGAALG
SLIIAGLISELGSWRMSFVVAGVGTVLAGFVAWWYIRNSPREHSGVNELEARHIEEAHAREHSAEPTNLSGRSLDFFKYR
SVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKTMGGASFLIFMSGFVGELVGGWIADKWKEAGGRPNVVMRTLFGI
AAVVATVSIFSVAYVTDAVAVVALLSSTLFFLRWCGLFWSVPSMLGTRNKIGFLGGVMNLGGNIAGISVPIIVGLIVQAT
GSYFLALMFFAACGVGLLFASTNIDYETKIPV

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=362, Percent_Identity=24.0331491712707, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI9945322, Length=365, Percent_Identity=26.027397260274, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI9966811, Length=370, Percent_Identity=25.1351351351351, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4885441, Length=365, Percent_Identity=24.1095890410959, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI154350196, Length=380, Percent_Identity=22.3684210526316, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI21322234, Length=362, Percent_Identity=24.8618784530387, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI148743791, Length=395, Percent_Identity=24.0506329113924, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789152, Length=423, Percent_Identity=28.3687943262411, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI2367379, Length=395, Percent_Identity=31.1392405063291, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082320, Length=394, Percent_Identity=27.6649746192893, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789515, Length=410, Percent_Identity=29.5121951219512, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI87082071, Length=389, Percent_Identity=26.4781491002571, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788573, Length=327, Percent_Identity=24.1590214067278, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI2367193, Length=396, Percent_Identity=21.7171717171717, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082310, Length=289, Percent_Identity=23.8754325259516, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=353, Percent_Identity=26.0623229461756, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=424, Percent_Identity=23.8207547169811, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554962, Length=370, Percent_Identity=24.5945945945946, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533554, Length=415, Percent_Identity=24.3373493975904, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=430, Percent_Identity=24.6511627906977, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=278, Percent_Identity=24.4604316546763, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=339, Percent_Identity=21.2389380530973, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=305, Percent_Identity=24.5901639344262, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639764, Length=454, Percent_Identity=24.2290748898678, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45550460, Length=453, Percent_Identity=25.1655629139073, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24584153, Length=378, Percent_Identity=26.4550264550265, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655255, Length=420, Percent_Identity=25.2380952380952, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573299, Length=394, Percent_Identity=26.1421319796954, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24658658, Length=437, Percent_Identity=25.1716247139588, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654215, Length=389, Percent_Identity=25.1928020565553, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19922400, Length=389, Percent_Identity=25.1928020565553, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24655271, Length=402, Percent_Identity=25.8706467661692, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20130135, Length=402, Percent_Identity=25.8706467661692, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24583789, Length=408, Percent_Identity=24.7549019607843, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641682, Length=437, Percent_Identity=24.9427917620137, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573708, Length=377, Percent_Identity=26.525198938992, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573707, Length=377, Percent_Identity=26.525198938992, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484226, Length=371, Percent_Identity=25.0673854447439, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24580790, Length=374, Percent_Identity=24.5989304812834, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20130167, Length=411, Percent_Identity=22.6277372262774, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24658674, Length=405, Percent_Identity=23.4567901234568, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550495, Length=391, Percent_Identity=24.0409207161125, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24653727, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19920686, Length=257, Percent_Identity=24.5136186770428, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648416, Length=381, Percent_Identity=24.9343832020997, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356189, Length=381, Percent_Identity=24.9343832020997, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24658666, Length=402, Percent_Identity=23.3830845771144, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46668; Mature: 46668

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTSQAGTLTATRSSVRWKIFLMMLMLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSSFFWTYAFMQIPGGMLADKYKPRIVIACATVFWGFFQAIAAVCTNATSLLLTRLGLGA
HHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
AEAPIYPAGGKLNAIWMTQNERGRGATLLDGGAPLGAALGSLIIAGLISELGSWRMSFVV
CCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVGTVLAGFVAWWYIRNSPREHSGVNELEARHIEEAHAREHSAEPTNLSGRSLDFFKYR
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
SVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKTMGGASFLIFMSGFVGELVGGWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
DKWKEAGGRPNVVMRTLFGIAAVVATVSIFSVAYVTDAVAVVALLSSTLFFLRWCGLFWS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPSMLGTRNKIGFLGGVMNLGGNIAGISVPIIVGLIVQATGSYFLALMFFAACGVGLLFA
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
STNIDYETKIPV
ECCCCCEECCCC
>Mature Secondary Structure
MQTTSQAGTLTATRSSVRWKIFLMMLMLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSSFFWTYAFMQIPGGMLADKYKPRIVIACATVFWGFFQAIAAVCTNATSLLLTRLGLGA
HHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
AEAPIYPAGGKLNAIWMTQNERGRGATLLDGGAPLGAALGSLIIAGLISELGSWRMSFVV
CCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVGTVLAGFVAWWYIRNSPREHSGVNELEARHIEEAHAREHSAEPTNLSGRSLDFFKYR
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
SVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKTMGGASFLIFMSGFVGELVGGWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
DKWKEAGGRPNVVMRTLFGIAAVVATVSIFSVAYVTDAVAVVALLSSTLFFLRWCGLFWS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPSMLGTRNKIGFLGGVMNLGGNIAGISVPIIVGLIVQATGSYFLALMFFAACGVGLLFA
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
STNIDYETKIPV
ECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]