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The map label for this gene is tcp [H]

Identifier: 73539742

GI number: 73539742

Start: 47892

End: 49691

Strand: Reverse

Name: tcp [H]

Synonym: Reut_A0036

Alternate gene names: 73539742

Gene position: 49691-47892 (Counterclockwise)

Preceding gene: 73539750

Following gene: 73539739

Centisome position: 1.31

GC content: 66.67

Gene sequence:

>1800_bases
ATGTTCTCAACCGTCCGCGCCCGGATCATGGCCCTTTGCGTGGCCATTGTCGTCGTCGCCCTGGCTCTCAACGCGGCGCT
CAGCCACCTGGTCACACGCCGCTACAACCAGGAAGCCATCGACAGCAGCCTGACCGCCGTGCAGAACGGCCATGCCGCTG
CCATCAACGACTGGGTCGCATCGCACAGCCAGATGATCAACTCGCTGCAGGACGCCGTGCTGCAGCCCGAACCCGACGCT
GCGCTCAAGCAGATTGCCGATGCCGGCGGCTTTACCAACGTCTACGTCGGCTACGCGGACAAGACCGCCAAGTTCTCTAA
CCCGACTGGCATCCCGCCCGGTTATGACCCGACCGGCCGCCCCTGGTACAAGCAGGCCGTGGGCGCAGGCAAGCCGGTGG
TGACGCCGCCCTATGTCGATGCCGGCAGCGGCAAGCTGGTGGTCGCCTTCGCAGCGCCCATCGTGCGTGATGGTGGCGTG
AAAGGCGTTGTCTCAGGCGACGTGGCCATGGACACCGTGATCGCCAACGTCAAGGCCATCCACCCGACGCCGGCCAGCTT
CGGCATGCTGGTGTCGAAGAACGGACTGATCGTCGCGCACCCCGACGACAAGCTCACGCTCAAGCCGGTGTCGGAACTCG
TGCCCGCGCTCGGCGCGGACAAGCTCGCATCGCTGCCCGGCGCGGCGGAGCCGCTCGAGGTGGAAGTGGCCGGTACCGCC
AAGCTGCTGCGCGCACGCGAGGTCCCGAACTCGGACTGGATGGTGATTGTCGCCCTCGACAAGTCGGAAGCCACGGCCGG
CATGCGTTCGACGATGATCGCCTCGATCGTCGCGCTGCTCGTGATTGCGTGCGTGGCCGCAGCCGTCACCGGCGCCGTGA
CGGCCGTGTCATTCCGCCGCCTGTCGCAGATCCGCGACGCGATGCGCGCGATCGGCACCGGCGACGGCGACCTCACGCAG
CGCTTGCCGGCCAACGGCCGCGATGAAGTCGCCCAGATTGCCGTGGCGTTCAACACGTTCGCCGACAAGCTGTGCACCGT
CATGCGCGACATCCGCGACACCAGCGAATCGGTGCGCGCCGCGTCCGAGGAAATCGCAGCCGGCAATATCGACCTGTCGC
GCCGCACCGAAAGCGCCGCGGCCAGCCTCGAGCAAACTGCCGCGTCGATGGAAGAAATCACCGCCACCGTATCGCAGTCC
GCCAACTCTGCCCAGCAGGCCAATGCATCGGTTGGCGCGGCGTCACGCGTGGCCGAGAGCGGCGGCGTGGTGATCGGCGA
AGTCATCAGCACCATGGGCGAGATCGAAAGCGCATCGGTGCGCGTGTCGGACATCATCAACGTGATCGAAGGCATCGCGT
TCCAGACCAACATCCTCGCGCTCAATGCCGCAGTCGAAGCTGCTCGCGCCGGCGACCAGGGCCGCGGCTTCGCGGTGGTG
GCGGGCGAGGTGCGCGCGCTGGCGCAACGCAGCGCGCAGGCCGCCAAGGAAATCAAGACGTTGATTGAAACGACCGTGGG
TAGCGTGACCACAGGCTCGAGCCAGGTGCAGCGTGCCGGCGCAACCATGCACGAGATCGTCAGCAACGTGTCGAAGGTGA
CGAGCATCATCGCCGAAATCACGCAGGCCGCCATCGAGCAGACGCGCGGCATTCACGAAGTGAACAAGGCAGTGACGCAG
CTCGACGAGATGGTGCAGCAGAACGCGGCGCTGGTGGAGCAATCCACGGCGGCCGCCGCAGCATTGCAAACGCAGGCGGC
AAGCCTGGCGGGGGCGGTGGGGCAGTTCAGGCTCGGTTGA

Upstream 100 bases:

>100_bases
GCATTGGTCGGCTCAAGTCGTCGCGAAGGCCTCCGTTTACCTGCCCAGTGGAGATCCCACACATGACCCCCCAAAAATTC
CCTACGAAGGAAACTGCCCG

Downstream 100 bases:

>100_bases
GTTCCCGAGCCCTGGCAGCGTGCCGCGCAATATTGCGCCGGCACGCTGCCAGGAATCATGACGCCAGTGTATTGAGCCGG
GCGTTGAGGCGCCCGCGCGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MFSTVRARIMALCVAIVVVALALNAALSHLVTRRYNQEAIDSSLTAVQNGHAAAINDWVASHSQMINSLQDAVLQPEPDA
ALKQIADAGGFTNVYVGYADKTAKFSNPTGIPPGYDPTGRPWYKQAVGAGKPVVTPPYVDAGSGKLVVAFAAPIVRDGGV
KGVVSGDVAMDTVIANVKAIHPTPASFGMLVSKNGLIVAHPDDKLTLKPVSELVPALGADKLASLPGAAEPLEVEVAGTA
KLLRAREVPNSDWMVIVALDKSEATAGMRSTMIASIVALLVIACVAAAVTGAVTAVSFRRLSQIRDAMRAIGTGDGDLTQ
RLPANGRDEVAQIAVAFNTFADKLCTVMRDIRDTSESVRAASEEIAAGNIDLSRRTESAAASLEQTAASMEEITATVSQS
ANSAQQANASVGAASRVAESGGVVIGEVISTMGEIESASVRVSDIINVIEGIAFQTNILALNAAVEAARAGDQGRGFAVV
AGEVRALAQRSAQAAKEIKTLIETTVGSVTTGSSQVQRAGATMHEIVSNVSKVTSIIAEITQAAIEQTRGIHEVNKAVTQ
LDEMVQQNAALVEQSTAAAAALQTQAASLAGAVGQFRLG

Sequences:

>Translated_599_residues
MFSTVRARIMALCVAIVVVALALNAALSHLVTRRYNQEAIDSSLTAVQNGHAAAINDWVASHSQMINSLQDAVLQPEPDA
ALKQIADAGGFTNVYVGYADKTAKFSNPTGIPPGYDPTGRPWYKQAVGAGKPVVTPPYVDAGSGKLVVAFAAPIVRDGGV
KGVVSGDVAMDTVIANVKAIHPTPASFGMLVSKNGLIVAHPDDKLTLKPVSELVPALGADKLASLPGAAEPLEVEVAGTA
KLLRAREVPNSDWMVIVALDKSEATAGMRSTMIASIVALLVIACVAAAVTGAVTAVSFRRLSQIRDAMRAIGTGDGDLTQ
RLPANGRDEVAQIAVAFNTFADKLCTVMRDIRDTSESVRAASEEIAAGNIDLSRRTESAAASLEQTAASMEEITATVSQS
ANSAQQANASVGAASRVAESGGVVIGEVISTMGEIESASVRVSDIINVIEGIAFQTNILALNAAVEAARAGDQGRGFAVV
AGEVRALAQRSAQAAKEIKTLIETTVGSVTTGSSQVQRAGATMHEIVSNVSKVTSIIAEITQAAIEQTRGIHEVNKAVTQ
LDEMVQQNAALVEQSTAAAAALQTQAASLAGAVGQFRLG
>Mature_599_residues
MFSTVRARIMALCVAIVVVALALNAALSHLVTRRYNQEAIDSSLTAVQNGHAAAINDWVASHSQMINSLQDAVLQPEPDA
ALKQIADAGGFTNVYVGYADKTAKFSNPTGIPPGYDPTGRPWYKQAVGAGKPVVTPPYVDAGSGKLVVAFAAPIVRDGGV
KGVVSGDVAMDTVIANVKAIHPTPASFGMLVSKNGLIVAHPDDKLTLKPVSELVPALGADKLASLPGAAEPLEVEVAGTA
KLLRAREVPNSDWMVIVALDKSEATAGMRSTMIASIVALLVIACVAAAVTGAVTAVSFRRLSQIRDAMRAIGTGDGDLTQ
RLPANGRDEVAQIAVAFNTFADKLCTVMRDIRDTSESVRAASEEIAAGNIDLSRRTESAAASLEQTAASMEEITATVSQS
ANSAQQANASVGAASRVAESGGVVIGEVISTMGEIESASVRVSDIINVIEGIAFQTNILALNAAVEAARAGDQGRGFAVV
AGEVRALAQRSAQAAKEIKTLIETTVGSVTTGSSQVQRAGATMHEIVSNVSKVTSIIAEITQAAIEQTRGIHEVNKAVTQ
LDEMVQQNAALVEQSTAAAAALQTQAASLAGAVGQFRLG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=389, Percent_Identity=46.5295629820051, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1788195, Length=283, Percent_Identity=55.1236749116608, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1788194, Length=283, Percent_Identity=52.6501766784452, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=47.8395061728395, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1789453, Length=322, Percent_Identity=38.1987577639752, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61759; Mature: 61759

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTVRARIMALCVAIVVVALALNAALSHLVTRRYNQEAIDSSLTAVQNGHAAAINDWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHH
SHSQMINSLQDAVLQPEPDAALKQIADAGGFTNVYVGYADKTAKFSNPTGIPPGYDPTGR
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
PWYKQAVGAGKPVVTPPYVDAGSGKLVVAFAAPIVRDGGVKGVVSGDVAMDTVIANVKAI
CHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCCCEEEECCHHHHHHHHHHHEE
HPTPASFGMLVSKNGLIVAHPDDKLTLKPVSELVPALGADKLASLPGAAEPLEVEVAGTA
CCCCCCCCCEEECCCEEEECCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEECCHH
KLLRAREVPNSDWMVIVALDKSEATAGMRSTMIASIVALLVIACVAAAVTGAVTAVSFRR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQIRDAMRAIGTGDGDLTQRLPANGRDEVAQIAVAFNTFADKLCTVMRDIRDTSESVRA
HHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASEEIAAGNIDLSRRTESAAASLEQTAASMEEITATVSQSANSAQQANASVGAASRVAES
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHC
GGVVIGEVISTMGEIESASVRVSDIINVIEGIAFQTNILALNAAVEAARAGDQGRGFAVV
CCEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEE
AGEVRALAQRSAQAAKEIKTLIETTVGSVTTGSSQVQRAGATMHEIVSNVSKVTSIIAEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TQAAIEQTRGIHEVNKAVTQLDEMVQQNAALVEQSTAAAAALQTQAASLAGAVGQFRLG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFSTVRARIMALCVAIVVVALALNAALSHLVTRRYNQEAIDSSLTAVQNGHAAAINDWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHH
SHSQMINSLQDAVLQPEPDAALKQIADAGGFTNVYVGYADKTAKFSNPTGIPPGYDPTGR
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
PWYKQAVGAGKPVVTPPYVDAGSGKLVVAFAAPIVRDGGVKGVVSGDVAMDTVIANVKAI
CHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCCCEEEECCHHHHHHHHHHHEE
HPTPASFGMLVSKNGLIVAHPDDKLTLKPVSELVPALGADKLASLPGAAEPLEVEVAGTA
CCCCCCCCCEEECCCEEEECCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEECCHH
KLLRAREVPNSDWMVIVALDKSEATAGMRSTMIASIVALLVIACVAAAVTGAVTAVSFRR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQIRDAMRAIGTGDGDLTQRLPANGRDEVAQIAVAFNTFADKLCTVMRDIRDTSESVRA
HHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASEEIAAGNIDLSRRTESAAASLEQTAASMEEITATVSQSANSAQQANASVGAASRVAES
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHC
GGVVIGEVISTMGEIESASVRVSDIINVIEGIAFQTNILALNAAVEAARAGDQGRGFAVV
CCEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEE
AGEVRALAQRSAQAAKEIKTLIETTVGSVTTGSSQVQRAGATMHEIVSNVSKVTSIIAEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TQAAIEQTRGIHEVNKAVTQLDEMVQQNAALVEQSTAAAAALQTQAASLAGAVGQFRLG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]