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The map label for this gene is yajO [H]

Identifier: 71908374

GI number: 71908374

Start: 2962315

End: 2963286

Strand: Reverse

Name: yajO [H]

Synonym: Daro_2761

Alternate gene names: 71908374

Gene position: 2963286-2962315 (Counterclockwise)

Preceding gene: 71908375

Following gene: 71908373

Centisome position: 65.83

GC content: 59.36

Gene sequence:

>972_bases
ATGGATTACGTACAGTTTGGCTCGACCGGCCTGAAGGTCTCACGCCTTGCCCTTGGTTGCATGACTTACGGGACGCCCGA
CTGGCGGCCATGGGTGCTCGATGAAGCGACGAGCCGGCCGTTCATTCGTCAGGCGCTCGATCTTGGGATCAATTTCTTCG
ATACGGCAGACATGTATTCGCTTGGCGTTGGTGAATCGGTGGTTGGTCTAGCCTTGAAGGATTTTGCGCGGCGAGAGGAT
GTGGTCATTGCGACCAAGGTTTTCTACCCGATGAGCGACAAGCCCAATGATCGCGGCTTGTCGCGAAAGCATATTCTGGC
CAGCATCGATGCCTCGCTGAAACGCCTTGGCACTGATTATGTCGATCTGTACATCATCCACCGCTTCGACCCGCTGACCC
CGATCGACGAAACCCTGGCCGCACTCGATACCGTCGTGCGCTCGGGCAAAGCCCGCTATATCGGTGCCTCGTCAATGTTC
GCCTGGCAGTTCATGGCCATGCTGGCGCGACAACGCGAGCTGGGTTTGAGTTGTTTTGTCTCGATGCAGAATCATTTCAA
CCTGATCTATCGCGAGGAAGAACGGGAGATGCTGCCCCTTTGCCGCCATGAAGGCATTGCTGTTACCCCGTGGTCGCCGC
TGGCCCGCGGCCGGCTTGCCGGTGCGCAGCAGGCACAGACCAGGCGCGCGATGACCGACAATTTGGCGCATCAATGGTAT
GACCAGCAGGCCATGGAAGATGCCATCGTCGCGGCGGTGAATAAGGTCGCGCAGGCCCGTGGCGTACCACCGGCCCAGAT
CGCCATCGCCTGGGTTAATAGCCAGCCGGGGATTACAGCGCCGATCATTGGCGCTTCGAAGGAGCACCATCTGCCCGATG
CCATCGCCGGCAGCCAACTCAGGTTGAGTGCTGAGGAGCGGGCCATTCTCGAGGCGCCTTACCATCCACGTCCCGTCGTT
GGACACGACTGA

Upstream 100 bases:

>100_bases
ACTCCTCAAGCCGGGCGAGGTGATCGCGGCCAAGGATTTGTCGCTTGAAGTTTGCCCAGCAAATATTGACCCCGGAAGTT
TTGACTGGATTGGAGCAGAG

Downstream 100 bases:

>100_bases
GGCGGAGTCTGATGTTTTCTCATCTTGAGCGCCCTGTTGCGAAGCTTTCCGGCCCGAGGCAGGTCTTTGCCGATTCTGGC
CTGGGGTATATCGCCAACGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MDYVQFGSTGLKVSRLALGCMTYGTPDWRPWVLDEATSRPFIRQALDLGINFFDTADMYSLGVGESVVGLALKDFARRED
VVIATKVFYPMSDKPNDRGLSRKHILASIDASLKRLGTDYVDLYIIHRFDPLTPIDETLAALDTVVRSGKARYIGASSMF
AWQFMAMLARQRELGLSCFVSMQNHFNLIYREEEREMLPLCRHEGIAVTPWSPLARGRLAGAQQAQTRRAMTDNLAHQWY
DQQAMEDAIVAAVNKVAQARGVPPAQIAIAWVNSQPGITAPIIGASKEHHLPDAIAGSQLRLSAEERAILEAPYHPRPVV
GHD

Sequences:

>Translated_323_residues
MDYVQFGSTGLKVSRLALGCMTYGTPDWRPWVLDEATSRPFIRQALDLGINFFDTADMYSLGVGESVVGLALKDFARRED
VVIATKVFYPMSDKPNDRGLSRKHILASIDASLKRLGTDYVDLYIIHRFDPLTPIDETLAALDTVVRSGKARYIGASSMF
AWQFMAMLARQRELGLSCFVSMQNHFNLIYREEEREMLPLCRHEGIAVTPWSPLARGRLAGAQQAQTRRAMTDNLAHQWY
DQQAMEDAIVAAVNKVAQARGVPPAQIAIAWVNSQPGITAPIIGASKEHHLPDAIAGSQLRLSAEERAILEAPYHPRPVV
GHD
>Mature_323_residues
MDYVQFGSTGLKVSRLALGCMTYGTPDWRPWVLDEATSRPFIRQALDLGINFFDTADMYSLGVGESVVGLALKDFARRED
VVIATKVFYPMSDKPNDRGLSRKHILASIDASLKRLGTDYVDLYIIHRFDPLTPIDETLAALDTVVRSGKARYIGASSMF
AWQFMAMLARQRELGLSCFVSMQNHFNLIYREEEREMLPLCRHEGIAVTPWSPLARGRLAGAQQAQTRRAMTDNLAHQWY
DQQAMEDAIVAAVNKVAQARGVPPAQIAIAWVNSQPGITAPIIGASKEHHLPDAIAGSQLRLSAEERAILEAPYHPRPVV
GHD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=32.5806451612903, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=32.4675324675325, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=30.6451612903226, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=30.6451612903226, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=31.8885448916409, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=30.3225806451613, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI223718702, Length=199, Percent_Identity=30.1507537688442, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41152114, Length=201, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41327764, Length=184, Percent_Identity=29.3478260869565, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=55.5555555555556, Blast_Score=343, Evalue=6e-96,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=32.9230769230769, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=31.4121037463977, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788070, Length=321, Percent_Identity=31.1526479750779, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=283, Percent_Identity=31.095406360424, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI48994888, Length=310, Percent_Identity=27.0967741935484, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786400, Length=271, Percent_Identity=24.7232472324723, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=37.910447761194, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=27.9279279279279, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=29.4520547945205, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=29.8850574712644, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=319, Percent_Identity=26.6457680250784, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640980, Length=347, Percent_Identity=26.2247838616715, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45549126, Length=347, Percent_Identity=26.2247838616715, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646155, Length=319, Percent_Identity=30.0940438871473, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24646159, Length=165, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24644950, Length=303, Percent_Identity=25.4125412541254, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35921; Mature: 35921

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYVQFGSTGLKVSRLALGCMTYGTPDWRPWVLDEATSRPFIRQALDLGINFFDTADMYS
CCCCEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCEECCCCHHH
LGVGESVVGLALKDFARREDVVIATKVFYPMSDKPNDRGLSRKHILASIDASLKRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCE
VDLYIIHRFDPLTPIDETLAALDTVVRSGKARYIGASSMFAWQFMAMLARQRELGLSCFV
EEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHEE
SMQNHFNLIYREEEREMLPLCRHEGIAVTPWSPLARGRLAGAQQAQTRRAMTDNLAHQWY
EHHHCCEEEEECCHHHHHHHHHCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DQQAMEDAIVAAVNKVAQARGVPPAQIAIAWVNSQPGITAPIIGASKEHHLPDAIAGSQL
HHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCEECCCCCCCCCCHHCCCCE
RLSAEERAILEAPYHPRPVVGHD
EECHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MDYVQFGSTGLKVSRLALGCMTYGTPDWRPWVLDEATSRPFIRQALDLGINFFDTADMYS
CCCCEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCEECCCCHHH
LGVGESVVGLALKDFARREDVVIATKVFYPMSDKPNDRGLSRKHILASIDASLKRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCE
VDLYIIHRFDPLTPIDETLAALDTVVRSGKARYIGASSMFAWQFMAMLARQRELGLSCFV
EEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHEE
SMQNHFNLIYREEEREMLPLCRHEGIAVTPWSPLARGRLAGAQQAQTRRAMTDNLAHQWY
EHHHCCEEEEECCHHHHHHHHHCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DQQAMEDAIVAAVNKVAQARGVPPAQIAIAWVNSQPGITAPIIGASKEHHLPDAIAGSQL
HHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCEECCCCCCCCCCHHCCCCE
RLSAEERAILEAPYHPRPVVGHD
EECHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]