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The map label for this gene is moaE [H]

Identifier: 71908342

GI number: 71908342

Start: 2924673

End: 2925125

Strand: Reverse

Name: moaE [H]

Synonym: Daro_2729

Alternate gene names: 71908342

Gene position: 2925125-2924673 (Counterclockwise)

Preceding gene: 71908343

Following gene: 71908340

Centisome position: 64.99

GC content: 64.68

Gene sequence:

>453_bases
ATGACTGTCCGGGTTCAGGGAGCGGATTTCGATGTTGGTGCCGAACTGGCCGCATTGCGCGCCGGGGATGCCCGCGTCGG
GGCGCTGGCCAGCTTTCTTGGCCTCGTCCGCGATCTGAACGATGGGGCCAGCGTTTCGGAAATGACGCTCGAGCACTATC
CGGGCATGACCGAAAAGGCGCTTGAGGAGATCGTCGCTGAAGCCCGTGGTCGTTGGGAACTCTACGACGCGCTGGTCATC
CATCGTGTCGGGCCGCTCAAGCCCTGCGAGCAGATCGTGCTCGTGGCCGTCACCAGCGCCCATCGCGGCGAAGCTTTCGC
CGCCTGCGAGTTCATCATGGATTACCTGAAGACCCGGGCTCCGTTCTGGAAGCGCGAGGCGACGCCGGATGGCGGCCGTT
GGGTCGATGCCCGTGAGACCGACGACAGCGCGGCAGCGCGCTGGCAGAAATAA

Upstream 100 bases:

>100_bases
ATCTGGCACCGAACAATGTCTATCTGAACATGGTCAAAGAGAAGTACCCCAACCTGCGCTTCCTCGAAGCGCGCGAAGTG
GCGTAAGAAGGGGGCTGAGC

Downstream 100 bases:

>100_bases
TAAAGGGGAGCCGAGGCTCCCCTTGTTGTATCGGCTTTGTTCCGGACTCAGGTCCGGAAGCGGGCCACCGTCTCGTGCAG
CGAGGCGGACAGCGATTGCA

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTVRVQGADFDVGAELAALRAGDARVGALASFLGLVRDLNDGASVSEMTLEHYPGMTEKALEEIVAEARGRWELYDALVI
HRVGPLKPCEQIVLVAVTSAHRGEAFAACEFIMDYLKTRAPFWKREATPDGGRWVDARETDDSAAARWQK

Sequences:

>Translated_150_residues
MTVRVQGADFDVGAELAALRAGDARVGALASFLGLVRDLNDGASVSEMTLEHYPGMTEKALEEIVAEARGRWELYDALVI
HRVGPLKPCEQIVLVAVTSAHRGEAFAACEFIMDYLKTRAPFWKREATPDGGRWVDARETDDSAAARWQK
>Mature_149_residues
TVRVQGADFDVGAELAALRAGDARVGALASFLGLVRDLNDGASVSEMTLEHYPGMTEKALEEIVAEARGRWELYDALVIH
RVGPLKPCEQIVLVAVTSAHRGEAFAACEFIMDYLKTRAPFWKREATPDGGRWVDARETDDSAAARWQK

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=30.9734513274336, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787003, Length=139, Percent_Identity=63.3093525179856, Blast_Score=171, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356259, Length=123, Percent_Identity=34.9593495934959, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16477; Mature: 16346

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVQGADFDVGAELAALRAGDARVGALASFLGLVRDLNDGASVSEMTLEHYPGMTEKA
CEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHH
LEEIVAEARGRWELYDALVIHRVGPLKPCEQIVLVAVTSAHRGEAFAACEFIMDYLKTRA
HHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
PFWKREATPDGGRWVDARETDDSAAARWQK
CCCCCCCCCCCCEEECCCCCCCHHHHCCCC
>Mature Secondary Structure 
TVRVQGADFDVGAELAALRAGDARVGALASFLGLVRDLNDGASVSEMTLEHYPGMTEKA
EEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHH
LEEIVAEARGRWELYDALVIHRVGPLKPCEQIVLVAVTSAHRGEAFAACEFIMDYLKTRA
HHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
PFWKREATPDGGRWVDARETDDSAAARWQK
CCCCCCCCCCCCEEECCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]