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The map label for this gene is hflX [H]

Identifier: 71908333

GI number: 71908333

Start: 2913818

End: 2915224

Strand: Reverse

Name: hflX [H]

Synonym: Daro_2720

Alternate gene names: 71908333

Gene position: 2915224-2913818 (Counterclockwise)

Preceding gene: 71908334

Following gene: 71908332

Centisome position: 64.77

GC content: 60.13

Gene sequence:

>1407_bases
ATGGCGGCGCCTTCGGTATTGGCGGGTACTATCTGCCTTTGCCCATTTAAGAGAAGCAATCCCGGAATGCGAAGTGAAGT
AGAAGACAAGACCAGATACGCCGTTGCGGCGGCTGTGCAATTACCGAATGTCAGCGATATCGAGTTCGAGGCCTCATTGA
CCGAGTTACGCGAACTGGCAAAAACACTGGGCTTCAAGGTGGTCCATACGTTTGTGCAAAAACGCGCCGGGTTCGATACG
ACGGGCTACCTGGGCATTGGCAAGCGCCAGGAAATACACGATTTCGTCAATCATGGTGTCGAAGGCGAGGGGGCGATCCC
GGGGGCGGCCGCTTTTTCCGGCCAGATCGATGCCATCCTTGTCGACCATGAAATTTCACCGTCACAGGCGCGCAACCTCG
AAAAAGAGGTTGGCTGCGAGGTGATGGATCGCACCATGGTGATCCTCGAGATTTTTCACAACAACGCCCGTTCCCGGGCT
GCCCGGGCTCAGGTGGAGATCGCGCGCCTTGGCTACATGGCGCCGCGCCTGCGCGAGGCGGCAAAGCTGGCCGGGCCGCA
GGGGCGCCAGCGCAGCGGTGCCGGTGGTCGAGGGGGCGGTGAGTCGCACACCGAACTGGATCGCCGCAAAATTCGTGACC
GCATCGCCGAACTGCAACAGGAAATCGTTGCCATGGATGTCGAACGCAAGACGCAGCGTGCGCGGCGCCAGGAGCGGCAG
GGGCTGGCGGGCGTGGCGCTCGTTGGCTACACCAATGCCGGTAAATCCACCTTGATGCGAGCGCTGACCGGTAGTGAGGT
GCTCGTCGCCAATAAACTCTTCGCGACGCTCGACACCACCGTCCGCACCCTCCATCCGGAAAGCGTGCCGCGGGTGCTGG
TCAGTGACACTGTCGGCTTCATCAAGAATCTGCCGCACGGCCTGGTTGCCTCTTTCAAGTCAACGCTCGAAGAGGCGCTT
GATGCCTCACTGCTGCTTCACGTGATCGATGCGAGCGATCCCGGATTCGAGCGTCAGCTTCAGGTGACCGACGACGTGCT
GCACGAGATCGGTGCCGATGCCGTGCCGCGCATTCGGGTCTTCAACAAGATTGACCATGTCGGCGACTCAGAGGCGCAAG
CCGAATGCGAAGCAGCATTGCGGGAAAAATATCCGGATTGTGTCGTGATGAGTGCCCGTCGCCCGGATGAGGTCGCCAGG
TTGCGCCTGACGATCATCTCGTTTTTCCAGCAAGGCCTGGTTGAAGCTGAACTCTTCCTTCCATGGTCGGCGCAGCAACT
GCGTGGGGAGCTTTACGCCAGTTGCGAGGTGCTGGAGGAGCGTGCCGATGAAGAGGGGGCTTTCTTCCGTGTTCGCGGTG
AACCCGATACCTTGATGATCCTGCGCGAGCAGTTCGCACAGGCTTGA

Upstream 100 bases:

>100_bases
TGATTGGATGCACTCGGGTGCTCGAAGCCCGGGCGACGCGTGGTTTGTATCCCTGATATGGCTGCGGCGAGGCTTTTAGC
CTGCGGTTGGACCGCATTCT

Downstream 100 bases:

>100_bases
CGCCCTGCTTTTTCAGGCAGGGAGGCGGGCCTATGTACGGTTTTTCGACGGCGATTGGCTGCCGTTCCCGGTTCAAGCAT
CGGTACGCCATGCTAGAATC

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAAPSVLAGTICLCPFKRSNPGMRSEVEDKTRYAVAAAVQLPNVSDIEFEASLTELRELAKTLGFKVVHTFVQKRAGFDT
TGYLGIGKRQEIHDFVNHGVEGEGAIPGAAAFSGQIDAILVDHEISPSQARNLEKEVGCEVMDRTMVILEIFHNNARSRA
ARAQVEIARLGYMAPRLREAAKLAGPQGRQRSGAGGRGGGESHTELDRRKIRDRIAELQQEIVAMDVERKTQRARRQERQ
GLAGVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEAL
DASLLLHVIDASDPGFERQLQVTDDVLHEIGADAVPRIRVFNKIDHVGDSEAQAECEAALREKYPDCVVMSARRPDEVAR
LRLTIISFFQQGLVEAELFLPWSAQQLRGELYASCEVLEERADEEGAFFRVRGEPDTLMILREQFAQA

Sequences:

>Translated_468_residues
MAAPSVLAGTICLCPFKRSNPGMRSEVEDKTRYAVAAAVQLPNVSDIEFEASLTELRELAKTLGFKVVHTFVQKRAGFDT
TGYLGIGKRQEIHDFVNHGVEGEGAIPGAAAFSGQIDAILVDHEISPSQARNLEKEVGCEVMDRTMVILEIFHNNARSRA
ARAQVEIARLGYMAPRLREAAKLAGPQGRQRSGAGGRGGGESHTELDRRKIRDRIAELQQEIVAMDVERKTQRARRQERQ
GLAGVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEAL
DASLLLHVIDASDPGFERQLQVTDDVLHEIGADAVPRIRVFNKIDHVGDSEAQAECEAALREKYPDCVVMSARRPDEVAR
LRLTIISFFQQGLVEAELFLPWSAQQLRGELYASCEVLEERADEEGAFFRVRGEPDTLMILREQFAQA
>Mature_467_residues
AAPSVLAGTICLCPFKRSNPGMRSEVEDKTRYAVAAAVQLPNVSDIEFEASLTELRELAKTLGFKVVHTFVQKRAGFDTT
GYLGIGKRQEIHDFVNHGVEGEGAIPGAAAFSGQIDAILVDHEISPSQARNLEKEVGCEVMDRTMVILEIFHNNARSRAA
RAQVEIARLGYMAPRLREAAKLAGPQGRQRSGAGGRGGGESHTELDRRKIRDRIAELQQEIVAMDVERKTQRARRQERQG
LAGVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALD
ASLLLHVIDASDPGFERQLQVTDDVLHEIGADAVPRIRVFNKIDHVGDSEAQAECEAALREKYPDCVVMSARRPDEVARL
RLTIISFFQQGLVEAELFLPWSAQQLRGELYASCEVLEERADEEGAFFRVRGEPDTLMILREQFAQA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=190, Percent_Identity=38.4210526315789, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI310133118, Length=194, Percent_Identity=37.1134020618557, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI310124269, Length=180, Percent_Identity=37.7777777777778, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI310124267, Length=180, Percent_Identity=37.7777777777778, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI310124171, Length=180, Percent_Identity=37.7777777777778, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI310124169, Length=180, Percent_Identity=37.7777777777778, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1790615, Length=420, Percent_Identity=35.2380952380952, Blast_Score=218, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17561038, Length=253, Percent_Identity=32.8063241106719, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24650079, Length=267, Percent_Identity=34.0823970037453, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51478; Mature: 51347

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPSVLAGTICLCPFKRSNPGMRSEVEDKTRYAVAAAVQLPNVSDIEFEASLTELRELA
CCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHH
KTLGFKVVHTFVQKRAGFDTTGYLGIGKRQEIHDFVNHGVEGEGAIPGAAAFSGQIDAIL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEE
VDHEISPSQARNLEKEVGCEVMDRTMVILEIFHNNARSRAARAQVEIARLGYMAPRLREA
EECCCCHHHHHCCHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAGPQGRQRSGAGGRGGGESHTELDRRKIRDRIAELQQEIVAMDVERKTQRARRQERQ
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLAGVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTVGF
CCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKNLPHGLVASFKSTLEEALDASLLLHVIDASDPGFERQLQVTDDVLHEIGADAVPRIRV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
FNKIDHVGDSEAQAECEAALREKYPDCVVMSARRPDEVARLRLTIISFFQQGLVEAELFL
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PWSAQQLRGELYASCEVLEERADEEGAFFRVRGEPDTLMILREQFAQA
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AAPSVLAGTICLCPFKRSNPGMRSEVEDKTRYAVAAAVQLPNVSDIEFEASLTELRELA
CCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHH
KTLGFKVVHTFVQKRAGFDTTGYLGIGKRQEIHDFVNHGVEGEGAIPGAAAFSGQIDAIL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEE
VDHEISPSQARNLEKEVGCEVMDRTMVILEIFHNNARSRAARAQVEIARLGYMAPRLREA
EECCCCHHHHHCCHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAGPQGRQRSGAGGRGGGESHTELDRRKIRDRIAELQQEIVAMDVERKTQRARRQERQ
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLAGVALVGYTNAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPESVPRVLVSDTVGF
CCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKNLPHGLVASFKSTLEEALDASLLLHVIDASDPGFERQLQVTDDVLHEIGADAVPRIRV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
FNKIDHVGDSEAQAECEAALREKYPDCVVMSARRPDEVARLRLTIISFFQQGLVEAELFL
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PWSAQQLRGELYASCEVLEERADEEGAFFRVRGEPDTLMILREQFAQA
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]