Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 71908237

GI number: 71908237

Start: 2823130

End: 2823465

Strand: Reverse

Name: lspA [H]

Synonym: Daro_2624

Alternate gene names: 71908237

Gene position: 2823465-2823130 (Counterclockwise)

Preceding gene: 71908238

Following gene: 71908236

Centisome position: 62.73

GC content: 55.95

Gene sequence:

>336_bases
ATGTTGCTGAAAGGCGTGGCGAACCGGTGGCAAGGGTGGGAGTATAGCCTGCTCCTCGGCGGTGCCGTCGGCAACCTGGT
AGATCGCTTGGTCCAGGGAGCGGTCGTGGATTATCTGGACTTCCATGCCGGCGGCTGGCACTGGTCAGCCTTCAATCTCG
CCGATACGGCGCTTTGTCTGAGCGCCTTGATTCTTCTCTGGGGAACCTTGCTGTCGTCAGCTCAAAGCAAGGCGCCCCCT
TCCCTTAGCAAGGGCGCAGGAAATCTCGATGCAAATTCTGGCTATAAACCAAAACGAGGAACACAAAATGGCTCAACGAT
CCTTCTCACTATTTGA

Upstream 100 bases:

>100_bases
ATGGGTGCATGTTTCCACGCTGGAAAGGCGGGTACCCATCCTCTGATATAGCCCCATGGGGATGCCATTAGCCTTGGCCG
TCTCGGTGGGGTTGGCCGTC

Downstream 100 bases:

>100_bases
TCGTCGCACGCTGTCTGCCTTGATCCTCCTGGGCCTGGTCCATTGCGCTTCGGCAGCCGAGGAACCCTTGCCTCCTGATC
AGGCGTTTCGGCTCAAGGCG

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MLLKGVANRWQGWEYSLLLGGAVGNLVDRLVQGAVVDYLDFHAGGWHWSAFNLADTALCLSALILLWGTLLSSAQSKAPP
SLSKGAGNLDANSGYKPKRGTQNGSTILLTI

Sequences:

>Translated_111_residues
MLLKGVANRWQGWEYSLLLGGAVGNLVDRLVQGAVVDYLDFHAGGWHWSAFNLADTALCLSALILLWGTLLSSAQSKAPP
SLSKGAGNLDANSGYKPKRGTQNGSTILLTI
>Mature_111_residues
MLLKGVANRWQGWEYSLLLGGAVGNLVDRLVQGAVVDYLDFHAGGWHWSAFNLADTALCLSALILLWGTLLSSAQSKAPP
SLSKGAGNLDANSGYKPKRGTQNGSTILLTI

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=64, Percent_Identity=56.25, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 11770; Mature: 11770

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKGVANRWQGWEYSLLLGGAVGNLVDRLVQGAVVDYLDFHAGGWHWSAFNLADTALCL
CCCCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHH
SALILLWGTLLSSAQSKAPPSLSKGAGNLDANSGYKPKRGTQNGSTILLTI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MLLKGVANRWQGWEYSLLLGGAVGNLVDRLVQGAVVDYLDFHAGGWHWSAFNLADTALCL
CCCCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHH
SALILLWGTLLSSAQSKAPPSLSKGAGNLDANSGYKPKRGTQNGSTILLTI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA