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The map label for this gene is dsbD1 [H]

Identifier: 71908236

GI number: 71908236

Start: 2822706

End: 2823158

Strand: Reverse

Name: dsbD1 [H]

Synonym: Daro_2623

Alternate gene names: 71908236

Gene position: 2823158-2822706 (Counterclockwise)

Preceding gene: 71908237

Following gene: 71908235

Centisome position: 62.72

GC content: 52.54

Gene sequence:

>453_bases
ATGGCTCAACGATCCTTCTCACTATTTGATCGTCGCACGCTGTCTGCCTTGATCCTCCTGGGCCTGGTCCATTGCGCTTC
GGCAGCCGAGGAACCCTTGCCTCCTGATCAGGCGTTTCGGCTCAAGGCGTCCCTGAAGGGTAGCGATACGGTGGTGGCTG
AAATCATTCCTGCCAAGAAGCACTACCTCTACAAAAACAAGGTCCGCTTCGCCTTGAAGAACGCCAGCGGCTTCCGGATC
AAGGAGGTCAAACTACCTTCCGGCGAGATGAAGAACGATCCCTATTTTGGGCTGATTGAAGTCTACAAATCGCCCGTCGT
CGCGGAAATCGTTCTGGAACGCGCTCCCAAGTCTAAAGCCTTCACTCTGTATGCGTCTTATCAGGGGTGCAATGAGAAAC
TCGGCATCTGTTATCCGCCGATTGAGAAAACCATTGATATGAAGTTCGATTGA

Upstream 100 bases:

>100_bases
TTGCTGTCGTCAGCTCAAAGCAAGGCGCCCCCTTCCCTTAGCAAGGGCGCAGGAAATCTCGATGCAAATTCTGGCTATAA
ACCAAAACGAGGAACACAAA

Downstream 100 bases:

>100_bases
CGCCGGTTATCACATTTTCCCATTTCTGGCGTTTAGCCCATCTGCCATCTCTTGAAAGGTTTATTTTCATGTTAAAAAAG
CTCATTGCCTGCCTGTTAGC

Product: thioredoxin:cytochrome c biogenesis protein transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase 1; Disulfide reductase 1 [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MAQRSFSLFDRRTLSALILLGLVHCASAAEEPLPPDQAFRLKASLKGSDTVVAEIIPAKKHYLYKNKVRFALKNASGFRI
KEVKLPSGEMKNDPYFGLIEVYKSPVVAEIVLERAPKSKAFTLYASYQGCNEKLGICYPPIEKTIDMKFD

Sequences:

>Translated_150_residues
MAQRSFSLFDRRTLSALILLGLVHCASAAEEPLPPDQAFRLKASLKGSDTVVAEIIPAKKHYLYKNKVRFALKNASGFRI
KEVKLPSGEMKNDPYFGLIEVYKSPVVAEIVLERAPKSKAFTLYASYQGCNEKLGICYPPIEKTIDMKFD
>Mature_149_residues
AQRSFSLFDRRTLSALILLGLVHCASAAEEPLPPDQAFRLKASLKGSDTVVAEIIPAKKHYLYKNKVRFALKNASGFRIK
EVKLPSGEMKNDPYFGLIEVYKSPVVAEIVLERAPKSKAFTLYASYQGCNEKLGICYPPIEKTIDMKFD

Specific function: Involved in the formation of correct disulfide bonds in some periplasmic proteins and in the assembly of the periplasmic C-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=147, Percent_Identity=31.2925170068027, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 16802; Mature: 16671

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRSFSLFDRRTLSALILLGLVHCASAAEEPLPPDQAFRLKASLKGSDTVVAEIIPAKK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCHH
HYLYKNKVRFALKNASGFRIKEVKLPSGEMKNDPYFGLIEVYKSPVVAEIVLERAPKSKA
HHHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEHHHHHHCCHHHHHHHHCCCCCCE
FTLYASYQGCNEKLGICYPPIEKTIDMKFD
EEEEEECCCCCCCCCEEECCCCCCEECCCC
>Mature Secondary Structure 
AQRSFSLFDRRTLSALILLGLVHCASAAEEPLPPDQAFRLKASLKGSDTVVAEIIPAKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCHH
HYLYKNKVRFALKNASGFRIKEVKLPSGEMKNDPYFGLIEVYKSPVVAEIVLERAPKSKA
HHHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEHHHHHHCCHHHHHHHHCCCCCCE
FTLYASYQGCNEKLGICYPPIEKTIDMKFD
EEEEEECCCCCCCCCEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9353916; 10984043 [H]