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The map label for this gene is dnaJ1 [H]

Identifier: 71908085

GI number: 71908085

Start: 2667973

End: 2668980

Strand: Reverse

Name: dnaJ1 [H]

Synonym: Daro_2467

Alternate gene names: 71908085

Gene position: 2668980-2667973 (Counterclockwise)

Preceding gene: 71908086

Following gene: 71908080

Centisome position: 59.3

GC content: 60.62

Gene sequence:

>1008_bases
ATGGACATTGATCCTTACGAAATTCTCGATGTGGCCAAAGATTCAGGCCCGGTTGAGTGGAAACGGGCCTATCGTCGTCT
TGCCATGCGCTGGCACCCGGATCGTAATGCTCACCCGGAGGCCACCGAGCGTTTCAAGGCAATCAACATCGCCTACGAGC
GCCTGACGACCGGCGATTTGCCGGAAGAGAATGATGCCGAATCGCCGGAAAACCAAGCCGCTGAACCGGAAGAGAGTGTC
GCCAAGGCTGCTGATATCCGCCTGAACCTCGAGGTCAGCCTGGAAGAAGCCGCCACCGGTTGCCGCAAGACGGTTCATTA
CGCTCGCGGCAAGGATTGTCCGACCTGCGAGGGCAGCGGCGAGGCAGGCATGTCGCGGACCCGCTTTTGCGATGCCTGTC
ATGGTAGTGGCCGTATCCACGATGCTCAACGCAAGCTGGTTCGTTGTGATGCCTGTGACGGCCGAGGCTTGTTCAGGGAG
CGTATCTGCCCGGATTGCGGCGGCAGTGGTCGTGAAACGGATGATGTCAGCCTGACAATCACCGTGCCACCCGGCATGCT
GCCTGGCGATGAGCTGCGGCTGGCTGGGCAGGGCGAACCGGGCAACGATGAATGCACGGCAGGCGATCTGTATCTGACGC
TGATCATTCGTTCGCACCCGCTCTATCAGTTGCAAGGCCGCGATCTACATTTTCAGATGCCGGTCAGCGCGCTGGCGATG
ATTGCCGGGGCTGAGGTTGAACTACCATCCTTGAACGGTGTATTCGGTTATTCGCTGGCGCCTGGTGTTGCCGAGCGCCG
CGAGTTGCGGCTGGCCGGCAAGGGTTATCCGGGGCGTGGCACGAATCCGGTCGGCGATCTGGTGGTTGAACTGGAGCCAG
TGTTTCCGCACAAGCTCAGTGCTCGCCAGCGCAAGCTGCTTCTGCAGGCGAATGCGGCGTTGCTTGACGATGCCGCTGAG
GCATTGCCGGAAATCGCCGAGTGGCGGCAAAGTCACGGCCTCGACTGA

Upstream 100 bases:

>100_bases
AATCGTCGAATACAACCCGGATCGTGATCGCCACGGCACGACGGCGGCGTTGATTTCCAACATGATCGAGCAGATTTTGC
CGGTTGGCGCAAAGTAAGCC

Downstream 100 bases:

>100_bases
ACGCTGTCTTCAGGGGCGGGGATTGGGGTTGAAACTGAAGCGTTTGGGCAAGTCGGCAGCCGCAATGGTTTGCACGCGCA
GGTTTTGCCAGTGGATGTCG

Product: DnaJ central region:heat shock protein DnaJ, N-terminal:chaperone DnaJ, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDIDPYEILDVAKDSGPVEWKRAYRRLAMRWHPDRNAHPEATERFKAINIAYERLTTGDLPEENDAESPENQAAEPEESV
AKAADIRLNLEVSLEEAATGCRKTVHYARGKDCPTCEGSGEAGMSRTRFCDACHGSGRIHDAQRKLVRCDACDGRGLFRE
RICPDCGGSGRETDDVSLTITVPPGMLPGDELRLAGQGEPGNDECTAGDLYLTLIIRSHPLYQLQGRDLHFQMPVSALAM
IAGAEVELPSLNGVFGYSLAPGVAERRELRLAGKGYPGRGTNPVGDLVVELEPVFPHKLSARQRKLLLQANAALLDDAAE
ALPEIAEWRQSHGLD

Sequences:

>Translated_335_residues
MDIDPYEILDVAKDSGPVEWKRAYRRLAMRWHPDRNAHPEATERFKAINIAYERLTTGDLPEENDAESPENQAAEPEESV
AKAADIRLNLEVSLEEAATGCRKTVHYARGKDCPTCEGSGEAGMSRTRFCDACHGSGRIHDAQRKLVRCDACDGRGLFRE
RICPDCGGSGRETDDVSLTITVPPGMLPGDELRLAGQGEPGNDECTAGDLYLTLIIRSHPLYQLQGRDLHFQMPVSALAM
IAGAEVELPSLNGVFGYSLAPGVAERRELRLAGKGYPGRGTNPVGDLVVELEPVFPHKLSARQRKLLLQANAALLDDAAE
ALPEIAEWRQSHGLD
>Mature_335_residues
MDIDPYEILDVAKDSGPVEWKRAYRRLAMRWHPDRNAHPEATERFKAINIAYERLTTGDLPEENDAESPENQAAEPEESV
AKAADIRLNLEVSLEEAATGCRKTVHYARGKDCPTCEGSGEAGMSRTRFCDACHGSGRIHDAQRKLVRCDACDGRGLFRE
RICPDCGGSGRETDDVSLTITVPPGMLPGDELRLAGQGEPGNDECTAGDLYLTLIIRSHPLYQLQGRDLHFQMPVSALAM
IAGAEVELPSLNGVFGYSLAPGVAERRELRLAGKGYPGRGTNPVGDLVVELEPVFPHKLSARQRKLLLQANAALLDDAAE
ALPEIAEWRQSHGLD

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360840, Length=343, Percent_Identity=24.7813411078717, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI205360838, Length=343, Percent_Identity=24.7813411078717, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786197, Length=347, Percent_Identity=30.835734870317, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787235, Length=295, Percent_Identity=28.135593220339, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17553096, Length=348, Percent_Identity=23.8505747126437, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17553098, Length=348, Percent_Identity=23.8505747126437, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17507263, Length=357, Percent_Identity=24.6498599439776, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17563890, Length=233, Percent_Identity=28.755364806867, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324265, Length=351, Percent_Identity=27.3504273504274, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323119, Length=386, Percent_Identity=24.3523316062176, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321094, Length=253, Percent_Identity=23.3201581027668, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646562, Length=339, Percent_Identity=25.9587020648968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646560, Length=339, Percent_Identity=25.9587020648968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646558, Length=339, Percent_Identity=25.9587020648968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646556, Length=339, Percent_Identity=25.9587020648968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357547, Length=339, Percent_Identity=25.9587020648968, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920464, Length=328, Percent_Identity=27.4390243902439, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28574949, Length=338, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45552813, Length=381, Percent_Identity=23.3595800524934, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549272, Length=381, Percent_Identity=23.3595800524934, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45552811, Length=381, Percent_Identity=23.3595800524934, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI20129487, Length=333, Percent_Identity=26.4264264264264, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584014, Length=333, Percent_Identity=26.4264264264264, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 36635; Mature: 36635

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDPYEILDVAKDSGPVEWKRAYRRLAMRWHPDRNAHPEATERFKAINIAYERLTTGDL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PEENDAESPENQAAEPEESVAKAADIRLNLEVSLEEAATGCRKTVHYARGKDCPTCEGSG
CCCCCCCCCCCCCCCCHHHHHHHHCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
EAGMSRTRFCDACHGSGRIHDAQRKLVRCDACDGRGLFRERICPDCGGSGRETDDVSLTI
CCCCCHHHHHHHHCCCCCEEHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
TVPPGMLPGDELRLAGQGEPGNDECTAGDLYLTLIIRSHPLYQLQGRDLHFQMPVSALAM
EECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCEEEECCHHHHHH
IAGAEVELPSLNGVFGYSLAPGVAERRELRLAGKGYPGRGTNPVGDLVVELEPVFPHKLS
HHCCCEECCCCCCEECCCCCCCHHHHHHEEEECCCCCCCCCCCCCCEEEEECCCCCCHHH
ARQRKLLLQANAALLDDAAEALPEIAEWRQSHGLD
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIDPYEILDVAKDSGPVEWKRAYRRLAMRWHPDRNAHPEATERFKAINIAYERLTTGDL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PEENDAESPENQAAEPEESVAKAADIRLNLEVSLEEAATGCRKTVHYARGKDCPTCEGSG
CCCCCCCCCCCCCCCCHHHHHHHHCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
EAGMSRTRFCDACHGSGRIHDAQRKLVRCDACDGRGLFRERICPDCGGSGRETDDVSLTI
CCCCCHHHHHHHHCCCCCEEHHHHHHEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
TVPPGMLPGDELRLAGQGEPGNDECTAGDLYLTLIIRSHPLYQLQGRDLHFQMPVSALAM
EECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCEEEECCHHHHHH
IAGAEVELPSLNGVFGYSLAPGVAERRELRLAGKGYPGRGTNPVGDLVVELEPVFPHKLS
HHCCCEECCCCCCEECCCCCCCHHHHHHEEEECCCCCCCCCCCCCCEEEEECCCCCCHHH
ARQRKLLLQANAALLDDAAEALPEIAEWRQSHGLD
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA