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The map label for this gene is cbl [H]

Identifier: 71907754

GI number: 71907754

Start: 2299854

End: 2300789

Strand: Reverse

Name: cbl [H]

Synonym: Daro_2129

Alternate gene names: 71907754

Gene position: 2300789-2299854 (Counterclockwise)

Preceding gene: 71907755

Following gene: 71907746

Centisome position: 51.12

GC content: 58.33

Gene sequence:

>936_bases
ATGAATTTCCAGCAACTCAGAATCATCCGGGAAACGGTACGTCAGGATTTCAACCTGACCGAAGTGGCCAATGCCCTGTA
CACCTCGCAACCCGGGGTCAGCAAGCACATCAAGGATCTCGAAGACGAACTCGGGATTGAGGTCTTCATACGTCGCGGCA
AGCGTCTTCTCGGCCTGACCGAACCGGGCAAGGAACTGGTCGGCGTAGTCGAACGCATCCTGCTCGATACGCAGAATCTG
CGGCGCATTGCCGATCAGTTCGCCAGCCGGGAAACTGGCCATTTTGTCGTGGCGACAACACATACCCAGGCCCGTTATGC
GCTGCCCAAGATCATCCAGTGGTTCAAGGCCGATTACCCCAAGGTGCACTTGACGCTCTTACAAGGCAGTCCGCGCGAAA
TCGCCGAGCTGCTCGAGACAGGTCAGGCCGACGTTGGTATCGCCACCGAATCACTCGACAATGTGCCGGAACTCGCTTCC
TTCCCGTTCTATTCGTGGCATCACGCGGTGATCGTGCCTGACGGCCACCCGCTGCTCAATCTCGAAAAGGTCACGCTCGA
GGCTCTGGGTGAATACCCGATCATCACCTATCACGAAGGATTCACGGGGCGGGCGCATGTCGACAAGGGCTTCGCCGATG
CGGGCATCGTCCCGGATATCGTGCTGTCGGCCATCGATGCCGATGTGATCAAGACCTACGTCAGTCTTGGCTTGGGCGTC
GGTATCGTCGCCTCAGTAGCCTACGATCAGGAGCAGGATCGCAATCTCGCCCTGATTCCGGTTCCCGACCTGTTCCCGGC
GAACACAACGCGCATCGCCGTGCGTCGTGGCACCTATCTGCGCAGCTATGTTCATGCCTTTATCGAGAAGGTTTGCCCGG
ATCTCGGCGAGGATGCGATCAAGGCAGCCCTCAAACCGCAGTCCGGCAACGATTGA

Upstream 100 bases:

>100_bases
TGGTGACGATGTTTCTGTTCGACCCCGGCATATCCGGGTATTCAACAATAACGACAAACTGGCCGCCTGACGGCCTCCAG
AGAATAGAGCGGAGAACAGC

Downstream 100 bases:

>100_bases
GGCAGGGCTTGTTATTTGCCGAGAACAAATAAGTTGTTTTTCTTCGCGATTTCAAACTGGGTTCATTCCCGCTTTTTTAC
AATGAAGCCACTTTGATCAT

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNFQQLRIIRETVRQDFNLTEVANALYTSQPGVSKHIKDLEDELGIEVFIRRGKRLLGLTEPGKELVGVVERILLDTQNL
RRIADQFASRETGHFVVATTHTQARYALPKIIQWFKADYPKVHLTLLQGSPREIAELLETGQADVGIATESLDNVPELAS
FPFYSWHHAVIVPDGHPLLNLEKVTLEALGEYPIITYHEGFTGRAHVDKGFADAGIVPDIVLSAIDADVIKTYVSLGLGV
GIVASVAYDQEQDRNLALIPVPDLFPANTTRIAVRRGTYLRSYVHAFIEKVCPDLGEDAIKAALKPQSGND

Sequences:

>Translated_311_residues
MNFQQLRIIRETVRQDFNLTEVANALYTSQPGVSKHIKDLEDELGIEVFIRRGKRLLGLTEPGKELVGVVERILLDTQNL
RRIADQFASRETGHFVVATTHTQARYALPKIIQWFKADYPKVHLTLLQGSPREIAELLETGQADVGIATESLDNVPELAS
FPFYSWHHAVIVPDGHPLLNLEKVTLEALGEYPIITYHEGFTGRAHVDKGFADAGIVPDIVLSAIDADVIKTYVSLGLGV
GIVASVAYDQEQDRNLALIPVPDLFPANTTRIAVRRGTYLRSYVHAFIEKVCPDLGEDAIKAALKPQSGND
>Mature_311_residues
MNFQQLRIIRETVRQDFNLTEVANALYTSQPGVSKHIKDLEDELGIEVFIRRGKRLLGLTEPGKELVGVVERILLDTQNL
RRIADQFASRETGHFVVATTHTQARYALPKIIQWFKADYPKVHLTLLQGSPREIAELLETGQADVGIATESLDNVPELAS
FPFYSWHHAVIVPDGHPLLNLEKVTLEALGEYPIITYHEGFTGRAHVDKGFADAGIVPDIVLSAIDADVIKTYVSLGLGV
GIVASVAYDQEQDRNLALIPVPDLFPANTTRIAVRRGTYLRSYVHAFIEKVCPDLGEDAIKAALKPQSGND

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=308, Percent_Identity=52.9220779220779, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1787530, Length=311, Percent_Identity=44.6945337620579, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=29.1497975708502, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=24.9084249084249, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=24.609375, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788887, Length=233, Percent_Identity=26.1802575107296, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787879, Length=269, Percent_Identity=27.8810408921933, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788481, Length=263, Percent_Identity=26.2357414448669, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=242, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789204, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=225, Percent_Identity=28.4444444444444, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34470; Mature: 34470

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRIIRETVRQDFNLTEVANALYTSQPGVSKHIKDLEDELGIEVFIRRGKRLLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCCCEECCC
EPGKELVGVVERILLDTQNLRRIADQFASRETGHFVVATTHTQARYALPKIIQWFKADYP
CCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
KVHLTLLQGSPREIAELLETGQADVGIATESLDNVPELASFPFYSWHHAVIVPDGHPLLN
EEEEEEECCCHHHHHHHHHCCCCCCCEEHHHHCCCHHHHCCCCCCCCEEEEECCCCCCEE
LEKVTLEALGEYPIITYHEGFTGRAHVDKGFADAGIVPDIVLSAIDADVIKTYVSLGLGV
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIVASVAYDQEQDRNLALIPVPDLFPANTTRIAVRRGTYLRSYVHAFIEKVCPDLGEDAI
HHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHH
KAALKPQSGND
HHHCCCCCCCC
>Mature Secondary Structure
MNFQQLRIIRETVRQDFNLTEVANALYTSQPGVSKHIKDLEDELGIEVFIRRGKRLLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCCCEECCC
EPGKELVGVVERILLDTQNLRRIADQFASRETGHFVVATTHTQARYALPKIIQWFKADYP
CCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
KVHLTLLQGSPREIAELLETGQADVGIATESLDNVPELASFPFYSWHHAVIVPDGHPLLN
EEEEEEECCCHHHHHHHHHCCCCCCCEEHHHHCCCHHHHCCCCCCCCEEEEECCCCCCEE
LEKVTLEALGEYPIITYHEGFTGRAHVDKGFADAGIVPDIVLSAIDADVIKTYVSLGLGV
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIVASVAYDQEQDRNLALIPVPDLFPANTTRIAVRRGTYLRSYVHAFIEKVCPDLGEDAI
HHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHH
KAALKPQSGND
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]