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The map label for this gene is ompR [H]

Identifier: 71907609

GI number: 71907609

Start: 2129688

End: 2130419

Strand: Reverse

Name: ompR [H]

Synonym: Daro_1980

Alternate gene names: 71907609

Gene position: 2130419-2129688 (Counterclockwise)

Preceding gene: 71907613

Following gene: 71907608

Centisome position: 47.33

GC content: 63.8

Gene sequence:

>732_bases
ATGAGCGAACAACACCAACACCACCATATTCTTGTCGTCGATGACGATGCCCGGCTGCGCGACCTGCTGGTTCGCTACCT
GGGCGAACAGGGCTTCGAGGTCAAGGCCGCTGCCGATGGCCAGCAGATGGACAAGCTGCGCAGCCGCGAACACTACCACC
TGATCGTGCTCGACCTGATGATGCCGGGCGAAGATGGCCTGACCATCTGCCGCCGCCTGCGCGGCCAGGGCGACCAGACA
CCGATCATCATGCTGACGGCCAAGGGCGATGAAGTGGATCGTATCGTTGGCCTCGAAATGGGTGCCGACGATTACCTGCC
CAAGCCCTTCAACCCGCGTGAACTGCTCGCCCGCATCCACGCCGTGTTGCGCCGCCAGGGCAGCAAACCGCCAGGTGCTC
CGGAAGATGAGCCGGAAACGATCACCTTCAGCAACATCGAAGTCGATCTCGCAGCCCGCACGCTGAAGCGTGGCGAAGAA
CTGCAAGCGCTGACCACCGGTGAATTTGCCGTGCTGAAAGTGCTGCTCCAGCACCCGCGCCAGCCGCTTTCCCGCGACAA
GCTGATGTCGCTGGCCCGCGGCCGGGAACAAGGGCCATTCGACCGCGCCATCGACGTCCAGGTATCCCGCCTGCGCAAGC
TGATCGAAACTGATCCGGCCCAACCGCGCTACCTGCAGACCGTCTGGGGCTTCGGCTACGTCTTCGTGCCGGACGGCGCC
TCCCGGGACTGA

Upstream 100 bases:

>100_bases
AGCGGCTCGAAATGTAAGAATATGTTTCCCGGCCGGCCTCCGACAATCCTTGTTACCATTTGCCGCGATTCATTCACTGT
GTGCCTTTATCCTTGCCAGC

Downstream 100 bases:

>100_bases
TGCCAATGCCGCGCACGCTGCTGGCGCGCACCTTCCTGCTGTTGGCCATGCTGGTGCTGCTGACCACGGCGGCCTGGCTG
AGCCTGTTCCGCTATATCGA

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSEQHQHHHILVVDDDARLRDLLVRYLGEQGFEVKAAADGQQMDKLRSREHYHLIVLDLMMPGEDGLTICRRLRGQGDQT
PIIMLTAKGDEVDRIVGLEMGADDYLPKPFNPRELLARIHAVLRRQGSKPPGAPEDEPETITFSNIEVDLAARTLKRGEE
LQALTTGEFAVLKVLLQHPRQPLSRDKLMSLARGREQGPFDRAIDVQVSRLRKLIETDPAQPRYLQTVWGFGYVFVPDGA
SRD

Sequences:

>Translated_243_residues
MSEQHQHHHILVVDDDARLRDLLVRYLGEQGFEVKAAADGQQMDKLRSREHYHLIVLDLMMPGEDGLTICRRLRGQGDQT
PIIMLTAKGDEVDRIVGLEMGADDYLPKPFNPRELLARIHAVLRRQGSKPPGAPEDEPETITFSNIEVDLAARTLKRGEE
LQALTTGEFAVLKVLLQHPRQPLSRDKLMSLARGREQGPFDRAIDVQVSRLRKLIETDPAQPRYLQTVWGFGYVFVPDGA
SRD
>Mature_242_residues
SEQHQHHHILVVDDDARLRDLLVRYLGEQGFEVKAAADGQQMDKLRSREHYHLIVLDLMMPGEDGLTICRRLRGQGDQTP
IIMLTAKGDEVDRIVGLEMGADDYLPKPFNPRELLARIHAVLRRQGSKPPGAPEDEPETITFSNIEVDLAARTLKRGEEL
QALTTGEFAVLKVLLQHPRQPLSRDKLMSLARGREQGPFDRAIDVQVSRLRKLIETDPAQPRYLQTVWGFGYVFVPDGAS
RD

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=65.6779661016949, Blast_Score=333, Evalue=7e-93,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=36.4406779661017, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=42.436974789916, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=35.4978354978355, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=38.5281385281385, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=36.4035087719298, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=34.468085106383, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=33.7719298245614, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.1877729257642, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=33.1877729257642, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=32.7433628318584, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.4159292035398, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=31.9672131147541, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=30.9090909090909, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=37, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=37.9310344827586, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27516; Mature: 27385

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQHQHHHILVVDDDARLRDLLVRYLGEQGFEVKAAADGQQMDKLRSREHYHLIVLDLM
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEEEEEEE
MPGEDGLTICRRLRGQGDQTPIIMLTAKGDEVDRIVGLEMGADDYLPKPFNPRELLARIH
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHH
AVLRRQGSKPPGAPEDEPETITFSNIEVDLAARTLKRGEELQALTTGEFAVLKVLLQHPR
HHHHHCCCCCCCCCCCCCCEEEECCEEEHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCC
QPLSRDKLMSLARGREQGPFDRAIDVQVSRLRKLIETDPAQPRYLQTVWGFGYVFVPDGA
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCC
SRD
CCC
>Mature Secondary Structure 
SEQHQHHHILVVDDDARLRDLLVRYLGEQGFEVKAAADGQQMDKLRSREHYHLIVLDLM
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEEEEEEE
MPGEDGLTICRRLRGQGDQTPIIMLTAKGDEVDRIVGLEMGADDYLPKPFNPRELLARIH
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHH
AVLRRQGSKPPGAPEDEPETITFSNIEVDLAARTLKRGEELQALTTGEFAVLKVLLQHPR
HHHHHCCCCCCCCCCCCCCEEEECCEEEHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCC
QPLSRDKLMSLARGREQGPFDRAIDVQVSRLRKLIETDPAQPRYLQTVWGFGYVFVPDGA
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCC
SRD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]