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The map label for this gene is msrB

Identifier: 71907518

GI number: 71907518

Start: 2029754

End: 2030152

Strand: Reverse

Name: msrB

Synonym: Daro_1889

Alternate gene names: 71907518

Gene position: 2030152-2029754 (Counterclockwise)

Preceding gene: 71907519

Following gene: 71907514

Centisome position: 45.1

GC content: 59.4

Gene sequence:

>399_bases
ATGCCAAAAATCGAAAAGACCGACGCCGAATGGCGTGCCCAGCTCGATGAAAACGAATACCGCGTCACCCGCCAGAAAGG
CACCGAACGCGCCTTCACCGGTAAATACTGGGATACCCACGATGACGGCACCTACCGCTGCATCTGCTGTGGCGCCCCAC
TCTTTCGCTCAGAAACCAAGTTCGATTCCGGTTGCGGCTGGCCGAGCTTTCACACGCCTAACGATGAAAAGCTGATCGAC
GAGCACGTCGATCAGAGCTTCGGCATGATCCGCACCGAAGTCACCTGTCACGACTGCGGCGCCCACCTCGGTCACGTCTT
CGACGACGGCCCGGCGCCAACCGGGCTGCGCTACTGCATCAACTCGGCGTCGCTGAAGCTGGAGAAGGATGGGAAATGA

Upstream 100 bases:

>100_bases
CCCAGTTTCGACTGAGCCAGTCTGTCTGACCCCGTACCCGCTGCGCCGGGAATCATTTGCCGTTATGCCGGTCAGACCCG
GCAACCTCAAGGAAACAATC

Downstream 100 bases:

>100_bases
GGAGCGGGCGAGGTTTGCCGTAAGGCCGCAATTCTGCCGAAGTCGGCGGATGATCGCTTGCTATTGACCGGCAACGACGT
GCCCTAAGTGGAAGTAGCTG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MPKIEKTDAEWRAQLDENEYRVTRQKGTERAFTGKYWDTHDDGTYRCICCGAPLFRSETKFDSGCGWPSFHTPNDEKLID
EHVDQSFGMIRTEVTCHDCGAHLGHVFDDGPAPTGLRYCINSASLKLEKDGK

Sequences:

>Translated_132_residues
MPKIEKTDAEWRAQLDENEYRVTRQKGTERAFTGKYWDTHDDGTYRCICCGAPLFRSETKFDSGCGWPSFHTPNDEKLID
EHVDQSFGMIRTEVTCHDCGAHLGHVFDDGPAPTGLRYCINSASLKLEKDGK
>Mature_131_residues
PKIEKTDAEWRAQLDENEYRVTRQKGTERAFTGKYWDTHDDGTYRCICCGAPLFRSETKFDSGCGWPSFHTPNDEKLIDE
HVDQSFGMIRTEVTCHDCGAHLGHVFDDGPAPTGLRYCINSASLKLEKDGK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=55.2, Blast_Score=147, Evalue=2e-36,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=55.2, Blast_Score=147, Evalue=2e-36,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=55.2, Blast_Score=147, Evalue=2e-36,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=55.2, Blast_Score=147, Evalue=2e-36,
Organism=Homo sapiens, GI117606353, Length=133, Percent_Identity=45.8646616541353, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=54.2372881355932, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553450, Length=134, Percent_Identity=48.5074626865672, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=134, Percent_Identity=48.5074626865672, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=41.6666666666667, Blast_Score=106, Evalue=9e-25,
Organism=Drosophila melanogaster, GI221378664, Length=130, Percent_Identity=50, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI221378662, Length=137, Percent_Identity=47.4452554744526, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=46.7153284671533, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=46.7153284671533, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_DECAR (Q47EU6)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_285105.1
- ProteinModelPortal:   Q47EU6
- SMR:   Q47EU6
- STRING:   Q47EU6
- GeneID:   3569604
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_1889
- NMPDR:   fig|159087.4.peg.1900
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- BioCyc:   DARO159087:DARO_1889-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 14991; Mature: 14860

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIEKTDAEWRAQLDENEYRVTRQKGTERAFTGKYWDTHDDGTYRCICCGAPLFRSETK
CCCCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCC
FDSGCGWPSFHTPNDEKLIDEHVDQSFGMIRTEVTCHDCGAHLGHVFDDGPAPTGLRYCI
CCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHH
NSASLKLEKDGK
CCCCEEEECCCC
>Mature Secondary Structure 
PKIEKTDAEWRAQLDENEYRVTRQKGTERAFTGKYWDTHDDGTYRCICCGAPLFRSETK
CCCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCC
FDSGCGWPSFHTPNDEKLIDEHVDQSFGMIRTEVTCHDCGAHLGHVFDDGPAPTGLRYCI
CCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHH
NSASLKLEKDGK
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA