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The map label for this gene is dapL [H]

Identifier: 71907357

GI number: 71907357

Start: 1855373

End: 1856563

Strand: Reverse

Name: dapL [H]

Synonym: Daro_1727

Alternate gene names: 71907357

Gene position: 1856563-1855373 (Counterclockwise)

Preceding gene: 71907359

Following gene: 71907356

Centisome position: 41.25

GC content: 60.54

Gene sequence:

>1191_bases
GTGAATCCGCACCTCGCCCAACTCCAGCCCTACCCCTTCGAAAAGCTGCGCGCCCTGTTCGCTGGCGTCACGCCGAACCC
GCAATATAAAGAGATCAAGCTCTCCATCGGTGAGCCACAGCACCCGACGCCGGCGTTCATCATGGACGCGCTGGCCAACG
GCCTGAAGGGCCTTGCCAACTATCCCACGACGCAGGGTATTCCGCTGCTGCGCCAGACCATTGCCAAATGGTGCCGCCAT
CGCTACGGACTGGAACTGAATCCGGAAACGGAGATCCTGCCGGTCAACGGTTCCCGCGAAGCACTTTTTTCCTTCGCCCA
GACGGTCATTGATCCAAGCCGCGGCCACGTGCCGTTGATCGTCAGCCCGAATCCGTTCTACCAGATCTACGAGGGGGCCG
CCTACCTGTCCGGTGCCGAGCCGCGCTTCCTGAACAACCTGCCGGACAACGATTTCGCTTTCGACTATGCCAGCCTGAGC
GAAGAAGAATGGGCCCGCGTCCAGTTGTTCTACGTCTGCTCGCCGGGCAATCCGACCGGCAAGGTGCTGTCGCTGGCAGA
CTGGAAAACGCTGTTCGCGCTGTCCGACAAGTACGGCTTCATCATCGCCTCCGACGAGTGCTACTCGGAAATCTATTTCG
ACGAAGCCAATCCGCCGATCGGCGGACTCCAGGCGGCCAAGCTGCTCGGCCGTACGAATGAGCGCCTGGTCATGTTCTCC
AGTCTGTCCAAGCGCTCCAATGTGCCGGGCATGCGCTCCGGTTTTGTCGCCGGCGACGAGAAAATCCTGAAGAAATTCCT
GCTTTACCGCACCTACCACGGCTGCGCCATGGCGCCTCCAGTGCAGACAGCTTCCATCGCGGCCTGGAACGACGAGTCCC
ACGTGCTCGACAATCGCAATCAGTACCGCGAAAAATTCGCAGCCTGCACGCCGCTGATCGGCGAAGTGCTCGGCACCGGC
ATGCCGGACGCCAGCTTCTATCTGTGGGCGAAGACCCCGATTGCCGACACCGAGTTCGCTCGCGGCCTGCTCGAACACTA
TAATGTCGTCGTTCTGCCCGGCAGCTTCCTGGCCAGAGAAGTCAGGGGCGTCAATCCGGGCGCCAATTTTGTCCGTATTG
CGCTGGTCGCTTCGCTTGACGAGTGTCTCGAAGCAACCCAGCGCATCCGTCAATTTGCCCAACAACTGTAA

Upstream 100 bases:

>100_bases
CGAGGCCGAGAAAATCGACAGGATAAATGCACGTTTGTTCACAAGGCAGCGAAAGCGTTTTCAGGGATAATTCGCTTTTT
ACACCCATTCGACGCCTGAC

Downstream 100 bases:

>100_bases
TCAGAGAGAGCCCTCATGACTCATCCCCTGCAAGCCACCATCGAAGAACTCTGGGAACGCCGCACCGAGCTGTCCCCGCA
ATCCCCCCCGACCACCATCG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNPHLAQLQPYPFEKLRALFAGVTPNPQYKEIKLSIGEPQHPTPAFIMDALANGLKGLANYPTTQGIPLLRQTIAKWCRH
RYGLELNPETEILPVNGSREALFSFAQTVIDPSRGHVPLIVSPNPFYQIYEGAAYLSGAEPRFLNNLPDNDFAFDYASLS
EEEWARVQLFYVCSPGNPTGKVLSLADWKTLFALSDKYGFIIASDECYSEIYFDEANPPIGGLQAAKLLGRTNERLVMFS
SLSKRSNVPGMRSGFVAGDEKILKKFLLYRTYHGCAMAPPVQTASIAAWNDESHVLDNRNQYREKFAACTPLIGEVLGTG
MPDASFYLWAKTPIADTEFARGLLEHYNVVVLPGSFLAREVRGVNPGANFVRIALVASLDECLEATQRIRQFAQQL

Sequences:

>Translated_396_residues
MNPHLAQLQPYPFEKLRALFAGVTPNPQYKEIKLSIGEPQHPTPAFIMDALANGLKGLANYPTTQGIPLLRQTIAKWCRH
RYGLELNPETEILPVNGSREALFSFAQTVIDPSRGHVPLIVSPNPFYQIYEGAAYLSGAEPRFLNNLPDNDFAFDYASLS
EEEWARVQLFYVCSPGNPTGKVLSLADWKTLFALSDKYGFIIASDECYSEIYFDEANPPIGGLQAAKLLGRTNERLVMFS
SLSKRSNVPGMRSGFVAGDEKILKKFLLYRTYHGCAMAPPVQTASIAAWNDESHVLDNRNQYREKFAACTPLIGEVLGTG
MPDASFYLWAKTPIADTEFARGLLEHYNVVVLPGSFLAREVRGVNPGANFVRIALVASLDECLEATQRIRQFAQQL
>Mature_396_residues
MNPHLAQLQPYPFEKLRALFAGVTPNPQYKEIKLSIGEPQHPTPAFIMDALANGLKGLANYPTTQGIPLLRQTIAKWCRH
RYGLELNPETEILPVNGSREALFSFAQTVIDPSRGHVPLIVSPNPFYQIYEGAAYLSGAEPRFLNNLPDNDFAFDYASLS
EEEWARVQLFYVCSPGNPTGKVLSLADWKTLFALSDKYGFIIASDECYSEIYFDEANPPIGGLQAAKLLGRTNERLVMFS
SLSKRSNVPGMRSGFVAGDEKILKKFLLYRTYHGCAMAPPVQTASIAAWNDESHVLDNRNQYREKFAACTPLIGEVLGTG
MPDASFYLWAKTPIADTEFARGLLEHYNVVVLPGSFLAREVRGVNPGANFVRIALVASLDECLEATQRIRQFAQQL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=259, Percent_Identity=25.4826254826255, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169881279, Length=259, Percent_Identity=25.4826254826255, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=22.3350253807107, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=22.3350253807107, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788722, Length=370, Percent_Identity=28.9189189189189, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=23.3243967828418, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788332, Length=239, Percent_Identity=27.6150627615063, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=25.0620347394541, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=403, Percent_Identity=25.0620347394541, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=23.2098765432099, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24646114, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28573067, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28573065, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI18859735, Length=403, Percent_Identity=24.0694789081886, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44046; Mature: 44046

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPHLAQLQPYPFEKLRALFAGVTPNPQYKEIKLSIGEPQHPTPAFIMDALANGLKGLAN
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
YPTTQGIPLLRQTIAKWCRHRYGLELNPETEILPVNGSREALFSFAQTVIDPSRGHVPLI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEE
VSPNPFYQIYEGAAYLSGAEPRFLNNLPDNDFAFDYASLSEEEWARVQLFYVCSPGNPTG
ECCCCCEEHHCCCCEECCCCCHHHCCCCCCCCEECHHHCCCCCCCEEEEEEEECCCCCCC
KVLSLADWKTLFALSDKYGFIIASDECYSEIYFDEANPPIGGLQAAKLLGRTNERLVMFS
CEEEEHHHHHHEEECCCCEEEEECCHHHHHHEECCCCCCCCHHHHHHHHCCCCCEEEEEE
SLSKRSNVPGMRSGFVAGDEKILKKFLLYRTYHGCAMAPPVQTASIAAWNDESHVLDNRN
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHCCHH
QYREKFAACTPLIGEVLGTGMPDASFYLWAKTPIADTEFARGLLEHYNVVVLPGSFLARE
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEECCHHHHHH
VRGVNPGANFVRIALVASLDECLEATQRIRQFAQQL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPHLAQLQPYPFEKLRALFAGVTPNPQYKEIKLSIGEPQHPTPAFIMDALANGLKGLAN
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
YPTTQGIPLLRQTIAKWCRHRYGLELNPETEILPVNGSREALFSFAQTVIDPSRGHVPLI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEE
VSPNPFYQIYEGAAYLSGAEPRFLNNLPDNDFAFDYASLSEEEWARVQLFYVCSPGNPTG
ECCCCCEEHHCCCCEECCCCCHHHCCCCCCCCEECHHHCCCCCCCEEEEEEEECCCCCCC
KVLSLADWKTLFALSDKYGFIIASDECYSEIYFDEANPPIGGLQAAKLLGRTNERLVMFS
CEEEEHHHHHHEEECCCCEEEEECCHHHHHHEECCCCCCCCHHHHHHHHCCCCCEEEEEE
SLSKRSNVPGMRSGFVAGDEKILKKFLLYRTYHGCAMAPPVQTASIAAWNDESHVLDNRN
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHCCHH
QYREKFAACTPLIGEVLGTGMPDASFYLWAKTPIADTEFARGLLEHYNVVVLPGSFLARE
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEECCHHHHHH
VRGVNPGANFVRIALVASLDECLEATQRIRQFAQQL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA