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The map label for this gene is dapD

Identifier: 71907356

GI number: 71907356

Start: 1854539

End: 1855357

Strand: Reverse

Name: dapD

Synonym: Daro_1726

Alternate gene names: 71907356

Gene position: 1855357-1854539 (Counterclockwise)

Preceding gene: 71907357

Following gene: 71907355

Centisome position: 41.22

GC content: 60.93

Gene sequence:

>819_bases
ATGACTCATCCCCTGCAAGCCACCATCGAAGAACTCTGGGAACGCCGCACCGAGCTGTCCCCGCAATCCCCCCCGACCAC
CATCGCTGCGATCAATTCTGTGATCGGCGATCTGGATTCCGGCAAGCTGCGCGTCGCCGAGAAAATCGCCGGCGAATGGT
TCACCCACCAGTGGATCAAGAAGGCCGTGCTGCTGTCTTTCCGCGTCCGCGACAACCGCGTTCAGGAAGCCGGCGACATT
CGTTTCTACGACAAGGTCGACACCAAGTTCGAAGGCTGGACCGAAGAGCAGTTCCGCCAGGGCGGCTTCCGCGTGGTCCC
CGGCACCATCGTCCGCAAGGGTTCCTATGTCGCCAAGAACGCGGTACTGATGCCCTCCTTCGTCAATATCGGCGCCTACG
TCGATGAAAGCACCATGGTTGACACCTGGGTCACCGTCGGTTCCTGCGCCCAGATCGGCAAGAACGTACACCTCTCTGGT
GGCGTCGGCATCGGCGGCGTGCTTGAGCCGCTGCAGGCCAATCCGACCATCATCGAAGACAACTGCTTCATCGGCGCCCG
CTCCGAAGTCGTGGAAGGCGTCGTCATCGGCGAAAACTCGGTCCTTTCCATGGGTGTCTACATCGGCCAGAGCACCCCGA
TCTACGACCGTGAAACCGGTGAAGTCACCTATGGCCGTGTCCCCCCGGGCTCCGTCGTGATCAGCGGCACCCTGCCGAAG
GCCGATGGCAAGTACAGCCTGTATGCAGCCATCATCGTCAAGAAGGTTGATGCGCAGACCCGCTCGAAGACCAGCATCAA
CGAACTGCTGCGTCCGTAA

Upstream 100 bases:

>100_bases
TTTTGTCCGTATTGCGCTGGTCGCTTCGCTTGACGAGTGTCTCGAAGCAACCCAGCGCATCCGTCAATTTGCCCAACAAC
TGTAATCAGAGAGAGCCCTC

Downstream 100 bases:

>100_bases
ATCAATCCCCCACGAAGGTCTTGTCATGATTCTCGACAAACTGTTCCAGCTGATGGCCGAAAAGCAAGCCTCGGATATTT
TCATTTCCGCAGGCGCGCCT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTHPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIKKAVLLSFRVRDNRVQEAGDI
RFYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKNAVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPK
ADGKYSLYAAIIVKKVDAQTRSKTSINELLRP

Sequences:

>Translated_272_residues
MTHPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIKKAVLLSFRVRDNRVQEAGDI
RFYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKNAVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPK
ADGKYSLYAAIIVKKVDAQTRSKTSINELLRP
>Mature_271_residues
THPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIKKAVLLSFRVRDNRVQEAGDIR
FYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKNAVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPKA
DGKYSLYAAIIVKKVDAQTRSKTSINELLRP

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=268, Percent_Identity=71.6417910447761, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_DECAR (Q47FA8)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_284943.1
- ProteinModelPortal:   Q47FA8
- SMR:   Q47FA8
- STRING:   Q47FA8
- GeneID:   3568468
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_1726
- NMPDR:   fig|159087.4.peg.1739
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   DARO159087:DARO_1726-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29701; Mature: 29570

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIK
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
KAVLLSFRVRDNRVQEAGDIRFYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKN
HHHHHHEEECCCHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCEECCHHEEECCCCCCCC
AVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEECCHHHCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPK
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEEECCCC
ADGKYSLYAAIIVKKVDAQTRSKTSINELLRP
CCCCCEEEEEEEHHHHCCHHCCHHHHHHHHCC
>Mature Secondary Structure 
THPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIK
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
KAVLLSFRVRDNRVQEAGDIRFYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKN
HHHHHHEEECCCHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCEECCHHEEECCCCCCCC
AVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEECCHHHCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPK
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEEECCCC
ADGKYSLYAAIIVKKVDAQTRSKTSINELLRP
CCCCCEEEEEEEHHHHCCHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA