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The map label for this gene is speE [H]

Identifier: 71907352

GI number: 71907352

Start: 1850418

End: 1851287

Strand: Reverse

Name: speE [H]

Synonym: Daro_1722

Alternate gene names: 71907352

Gene position: 1851287-1850418 (Counterclockwise)

Preceding gene: 71907353

Following gene: 71907349

Centisome position: 41.13

GC content: 58.74

Gene sequence:

>870_bases
TTGAGCAAGCTTTACGAATTGCCCAGCCCGTTCGAAATCGAAACGGGCACCGTGCTGATGCTGGAGCCAGCCTGGGCCAA
GGCTGGTGAACTGCGCGCCCAGTTGCTTGATGAGAGCTACCCGAAGCCTTTTGTCATCGACGATGGCAAGTCACGCTTCC
TGTACTTCAACGTCCGCCTGATGCAGAGCGAAATGTCGCTCAAGGCACCGCACGACCTGGCCATTCGCTATACGCAGAAA
ATGATGGCCTTTCTGCTCTTCCAGCCCCGCCCGAAACGCATTGTGCTGATCGGTCTCGGTGGCGGTTCGCTGATCAAGTT
CTGCCACCGCCGCATGCCCGGCACGCAGCTGACGGCAATCGAACTCGACCCCAACGTGATTGCTTTTCGCGATGCCTTCA
TGGTGCCGCCAGACGATGAACGCCTGAAAATCATCGAGGCCGACGGCGCGGAATTTCTGGAAAACACCGAAAAAGGCATC
GATGCCCTGCTCGTCGATGCCTTCGACAAGACCGGCTTCGCACCCAGTCTGGCCAACCGCGAGTTCTTCGACAACGCCTA
CGCCAAGCTATCTGGCAACGGTGTGCTGGTCATCAATCTGGCTGGCGAGAAGGAAAGCTACGCCGGCCTGATCGGCGAAG
CGATGCACGTCTTTGACGATCAGGTCATCGTGATCTCGGTCCCCGACGATGGCAACCACGTACTCTATGCCTTCAAGGAA
CGCTATTTCGAGCCCCGCTGGCGCTGGTTGCACAATTACGCCAAGGAACTGCGCGCCAAGTTCGGCCTCGACTTCCCTGC
CTTCGTTCAAAAGATGGAACGCTCGACCAAGCTCGGCCTCGCCCGCCGCGAAGCCATCCGCCGCCGATAG

Upstream 100 bases:

>100_bases
GGCTTACCCGAAACTGCCCTTCACCTGGCTGGATACTGCCGCCGGCGACGAGTACGTTTTCATGCTGCACGCTACCGATT
TGCCGGGCTAAGTTGACCGC

Downstream 100 bases:

>100_bases
AGGCTACTTCGTCGCTTCCTCGGCCTGCGCCGCGCGCTGAGCCGCCTGCTGACTGGCGGCATCCAGGTCGCGTTGAACCC
GCTCCATCGTTGCACGCCCC

Product: spermidine synthase-like protein

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSKLYELPSPFEIETGTVLMLEPAWAKAGELRAQLLDESYPKPFVIDDGKSRFLYFNVRLMQSEMSLKAPHDLAIRYTQK
MMAFLLFQPRPKRIVLIGLGGGSLIKFCHRRMPGTQLTAIELDPNVIAFRDAFMVPPDDERLKIIEADGAEFLENTEKGI
DALLVDAFDKTGFAPSLANREFFDNAYAKLSGNGVLVINLAGEKESYAGLIGEAMHVFDDQVIVISVPDDGNHVLYAFKE
RYFEPRWRWLHNYAKELRAKFGLDFPAFVQKMERSTKLGLARREAIRRR

Sequences:

>Translated_289_residues
MSKLYELPSPFEIETGTVLMLEPAWAKAGELRAQLLDESYPKPFVIDDGKSRFLYFNVRLMQSEMSLKAPHDLAIRYTQK
MMAFLLFQPRPKRIVLIGLGGGSLIKFCHRRMPGTQLTAIELDPNVIAFRDAFMVPPDDERLKIIEADGAEFLENTEKGI
DALLVDAFDKTGFAPSLANREFFDNAYAKLSGNGVLVINLAGEKESYAGLIGEAMHVFDDQVIVISVPDDGNHVLYAFKE
RYFEPRWRWLHNYAKELRAKFGLDFPAFVQKMERSTKLGLARREAIRRR
>Mature_288_residues
SKLYELPSPFEIETGTVLMLEPAWAKAGELRAQLLDESYPKPFVIDDGKSRFLYFNVRLMQSEMSLKAPHDLAIRYTQKM
MAFLLFQPRPKRIVLIGLGGGSLIKFCHRRMPGTQLTAIELDPNVIAFRDAFMVPPDDERLKIIEADGAEFLENTEKGID
ALLVDAFDKTGFAPSLANREFFDNAYAKLSGNGVLVINLAGEKESYAGLIGEAMHVFDDQVIVISVPDDGNHVLYAFKER
YFEPRWRWLHNYAKELRAKFGLDFPAFVQKMERSTKLGLARREAIRRR

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17570359, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 32956; Mature: 32824

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLYELPSPFEIETGTVLMLEPAWAKAGELRAQLLDESYPKPFVIDDGKSRFLYFNVRL
CCCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEE
MQSEMSLKAPHDLAIRYTQKMMAFLLFQPRPKRIVLIGLGGGSLIKFCHRRMPGTQLTAI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEE
ELDPNVIAFRDAFMVPPDDERLKIIEADGAEFLENTEKGIDALLVDAFDKTGFAPSLANR
EECCCEEEEECEEECCCCCCCEEEEECCCHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCC
EFFDNAYAKLSGNGVLVINLAGEKESYAGLIGEAMHVFDDQVIVISVPDDGNHVLYAFKE
HHHCCHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHH
RYFEPRWRWLHNYAKELRAKFGLDFPAFVQKMERSTKLGLARREAIRRR
HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLYELPSPFEIETGTVLMLEPAWAKAGELRAQLLDESYPKPFVIDDGKSRFLYFNVRL
CCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEE
MQSEMSLKAPHDLAIRYTQKMMAFLLFQPRPKRIVLIGLGGGSLIKFCHRRMPGTQLTAI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEE
ELDPNVIAFRDAFMVPPDDERLKIIEADGAEFLENTEKGIDALLVDAFDKTGFAPSLANR
EECCCEEEEECEEECCCCCCCEEEEECCCHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCC
EFFDNAYAKLSGNGVLVINLAGEKESYAGLIGEAMHVFDDQVIVISVPDDGNHVLYAFKE
HHHCCHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHH
RYFEPRWRWLHNYAKELRAKFGLDFPAFVQKMERSTKLGLARREAIRRR
HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]