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The map label for this gene is dprE1 [H]

Identifier: 71907339

GI number: 71907339

Start: 1836426

End: 1837724

Strand: Reverse

Name: dprE1 [H]

Synonym: Daro_1709

Alternate gene names: 71907339

Gene position: 1837724-1836426 (Counterclockwise)

Preceding gene: 71907340

Following gene: 71907338

Centisome position: 40.83

GC content: 58.35

Gene sequence:

>1299_bases
ATGGTGGCCGTAAGTTCATGGGGGCGCCTTTCAATTGATGAGCATACAGTGGTCGCTCTCAGTGATCGCACCCAGATCCT
GGCTTCTCTCAAGAATGCAGTACCCGGTCTTGCGCATGGCAAGGGGCGCAGCTACGGTGACGTCTGCCTGAATCCGGAAG
GCACGCTCTGGGTCATGACCGGGCTCGACCATTTCATCGCTTTCGACGACAGCAGTGGCCGCCTGGTGTGTGAGACTGGT
GTGCTGCTGCGGGACATCCAGCGACTGGTCATTCCGCGCGGCTGGATTCTGCCAGTAACGCCAGGGACTCAATTGGTGAC
CGTTGGGGGTGCCATTGCCAACGATGTGCACGGCAAGAACCACCATGTACTGGGTTCTTTCGGCGATCACGTACAGAGCC
TCACTCTCATCCGTACTGATGGCGAGGTCATCCAGTGCGGCCCGAATGAGCAGCCAGATTGGTTCGCCGCCACTGTCGGT
GGATTGGGCCTGACGGGCGTGATCACCCAGGCCGAAATCCAGTTGCGACGCGTGACCGGCCCATGGCTTGATACCGAGAC
CGTTCCCTATGCCAACCTGAACGAGTTCTTCCTGCTTGCTGATGACTCCGAGGCCGACTGGGAACACACGGTGTCTTGGA
TCGACTGCATCACTGGCGGTGGTGGACGCGGTTTGTTCATGCGCGGCAACCCCACCAATGCCGGAGATCGCCCGGCACCC
CAGGGGCGTAAGCTGACCATGCCCCCCGTGCCGCCCGTTTCCCTAGTCAATCGGCTGTCGCTGCGCCCCTTCAACATGGC
CTACTACCACCTCAAGAAGTGGCAGGCCGGAAGGGCCATCACCCACTACGAGCCGTTTTTCTACCCTCTCGACAATCTGC
TTGAGTGGAACCGGATGTATGGCCCGAAGGGCTTCTTCCAGTACCAGAGTGTGGTGCCACGAGACGTTGGGCAAGACGCT
ATTCAGGCCATGCTGAAGGAAATCGCCCGATCGGGTGACGGCTCCTTTTTGGCAGTGCTTAAGACTTTTGGCAACCGACA
GCCCGTCGGGATGATGAGCTTTCCACGGCCCGGTGTCACACTGGCGTTGGATTTCCCCAATCACGGGACTCGCACGCATA
AACTCTTCGAACGACTAGATGCCATTGTGCACGAAGCGAATGGTCGCATCTACATGGCCAAGGATGCACGCATGCCTAGA
GAACTGTTTGAGGCTGGCTATCCGCGCTTAGCCGAATTTATCCAATATCGAGACCCTGGCATCAGCTCAGGTCTATCACG
TCGCCTAATGGGAAGTTGA

Upstream 100 bases:

>100_bases
TGCACGACGACCCGCTCGTATTTGCAGTTAAAGATCGCGCAAGTCTCGGCGCGGGTGCCACTTTTTCAGCCATTTTGATC
GCCGGTACTATGGGGGTCTC

Downstream 100 bases:

>100_bases
ATGAAGCCCAAGAAGAGAATTGTCATCATCGGTGCCACCTCAGCGATCGCTGAACAGTGCGCCCGATTGTGGGCAAAAGA
GAATCCGTCTGAGATGGTTC

Product: FAD linked oxidase, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MVAVSSWGRLSIDEHTVVALSDRTQILASLKNAVPGLAHGKGRSYGDVCLNPEGTLWVMTGLDHFIAFDDSSGRLVCETG
VLLRDIQRLVIPRGWILPVTPGTQLVTVGGAIANDVHGKNHHVLGSFGDHVQSLTLIRTDGEVIQCGPNEQPDWFAATVG
GLGLTGVITQAEIQLRRVTGPWLDTETVPYANLNEFFLLADDSEADWEHTVSWIDCITGGGGRGLFMRGNPTNAGDRPAP
QGRKLTMPPVPPVSLVNRLSLRPFNMAYYHLKKWQAGRAITHYEPFFYPLDNLLEWNRMYGPKGFFQYQSVVPRDVGQDA
IQAMLKEIARSGDGSFLAVLKTFGNRQPVGMMSFPRPGVTLALDFPNHGTRTHKLFERLDAIVHEANGRIYMAKDARMPR
ELFEAGYPRLAEFIQYRDPGISSGLSRRLMGS

Sequences:

>Translated_432_residues
MVAVSSWGRLSIDEHTVVALSDRTQILASLKNAVPGLAHGKGRSYGDVCLNPEGTLWVMTGLDHFIAFDDSSGRLVCETG
VLLRDIQRLVIPRGWILPVTPGTQLVTVGGAIANDVHGKNHHVLGSFGDHVQSLTLIRTDGEVIQCGPNEQPDWFAATVG
GLGLTGVITQAEIQLRRVTGPWLDTETVPYANLNEFFLLADDSEADWEHTVSWIDCITGGGGRGLFMRGNPTNAGDRPAP
QGRKLTMPPVPPVSLVNRLSLRPFNMAYYHLKKWQAGRAITHYEPFFYPLDNLLEWNRMYGPKGFFQYQSVVPRDVGQDA
IQAMLKEIARSGDGSFLAVLKTFGNRQPVGMMSFPRPGVTLALDFPNHGTRTHKLFERLDAIVHEANGRIYMAKDARMPR
ELFEAGYPRLAEFIQYRDPGISSGLSRRLMGS
>Mature_432_residues
MVAVSSWGRLSIDEHTVVALSDRTQILASLKNAVPGLAHGKGRSYGDVCLNPEGTLWVMTGLDHFIAFDDSSGRLVCETG
VLLRDIQRLVIPRGWILPVTPGTQLVTVGGAIANDVHGKNHHVLGSFGDHVQSLTLIRTDGEVIQCGPNEQPDWFAATVG
GLGLTGVITQAEIQLRRVTGPWLDTETVPYANLNEFFLLADDSEADWEHTVSWIDCITGGGGRGLFMRGNPTNAGDRPAP
QGRKLTMPPVPPVSLVNRLSLRPFNMAYYHLKKWQAGRAITHYEPFFYPLDNLLEWNRMYGPKGFFQYQSVVPRDVGQDA
IQAMLKEIARSGDGSFLAVLKTFGNRQPVGMMSFPRPGVTLALDFPNHGTRTHKLFERLDAIVHEANGRIYMAKDARMPR
ELFEAGYPRLAEFIQYRDPGISSGLSRRLMGS

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 47718; Mature: 47718

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVSSWGRLSIDEHTVVALSDRTQILASLKNAVPGLAHGKGRSYGDVCLNPEGTLWVMT
CEEECCCCCEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEE
GLDHFIAFDDSSGRLVCETGVLLRDIQRLVIPRGWILPVTPGTQLVTVGGAIANDVHGKN
CCCEEEEEECCCCEEEEECCHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHCCCCCC
HHVLGSFGDHVQSLTLIRTDGEVIQCGPNEQPDWFAATVGGLGLTGVITQAEIQLRRVTG
CEEECCHHCCCEEEEEEECCCCEEEECCCCCCCEEEEECCCCCHHHEEEEEEEEEEEECC
PWLDTETVPYANLNEFFLLADDSEADWEHTVSWIDCITGGGGRGLFMRGNPTNAGDRPAP
CCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCC
QGRKLTMPPVPPVSLVNRLSLRPFNMAYYHLKKWQAGRAITHYEPFFYPLDNLLEWNRMY
CCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHC
GPKGFFQYQSVVPRDVGQDAIQAMLKEIARSGDGSFLAVLKTFGNRQPVGMMSFPRPGVT
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCEE
LALDFPNHGTRTHKLFERLDAIVHEANGRIYMAKDARMPRELFEAGYPRLAEFIQYRDPG
EEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHCCCC
ISSGLSRRLMGS
CHHHHHHHHCCC
>Mature Secondary Structure
MVAVSSWGRLSIDEHTVVALSDRTQILASLKNAVPGLAHGKGRSYGDVCLNPEGTLWVMT
CEEECCCCCEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEE
GLDHFIAFDDSSGRLVCETGVLLRDIQRLVIPRGWILPVTPGTQLVTVGGAIANDVHGKN
CCCEEEEEECCCCEEEEECCHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHCCCCCC
HHVLGSFGDHVQSLTLIRTDGEVIQCGPNEQPDWFAATVGGLGLTGVITQAEIQLRRVTG
CEEECCHHCCCEEEEEEECCCCEEEECCCCCCCEEEEECCCCCHHHEEEEEEEEEEEECC
PWLDTETVPYANLNEFFLLADDSEADWEHTVSWIDCITGGGGRGLFMRGNPTNAGDRPAP
CCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCC
QGRKLTMPPVPPVSLVNRLSLRPFNMAYYHLKKWQAGRAITHYEPFFYPLDNLLEWNRMY
CCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHC
GPKGFFQYQSVVPRDVGQDAIQAMLKEIARSGDGSFLAVLKTFGNRQPVGMMSFPRPGVT
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCEE
LALDFPNHGTRTHKLFERLDAIVHEANGRIYMAKDARMPRELFEAGYPRLAEFIQYRDPG
EEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHCCCC
ISSGLSRRLMGS
CHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]