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The map label for this gene is pip [H]

Identifier: 71907328

GI number: 71907328

Start: 1825424

End: 1826386

Strand: Reverse

Name: pip [H]

Synonym: Daro_1698

Alternate gene names: 71907328

Gene position: 1826386-1825424 (Counterclockwise)

Preceding gene: 71907333

Following gene: 71907327

Centisome position: 40.58

GC content: 61.89

Gene sequence:

>963_bases
ATGTTTTCCCCTCTTGAACCGCTGAGAACTGGCTATCTCGATGTCGGGGACGGGCACCGGCTATATTTCGAGACCTGCGG
AAATCCGCGTGGCCTGCCCGTTGTGGTGCTGCACGGCGGTCCTGGAAGTGGCACCAGCGCCAGAATGCGCACGCTCTATG
ACCCGGAGCGCTTCCATACAGTCCTCTTCGACCAGCGCGGCTGCGGGCGTTCGCTGCCTCAGGGAGAACTGCACGCCAAC
CATCTGAATGCGCTGATTGCCGACATCGAGCGCCTGCGCCTTCATCTCGGAATTGCACGCTGGCTGGTCAGCGGCGGCTC
ATGGGGCGCCACGCTGGCACTAGCCTATACCGCAAATACCCCACAGGCCGTACTCGGAATACTGGTGCGTAGCGTATTTC
TTGCCGGAGATCACGACATTCAATGGTTTTTTCAGGGCGCCAAAGCACTCGTTCCCCAAGCGTGGGAAGCCTTTGCCGCG
CAGGTCGCGCCAGAGAACTCCGACCTTCTGAGCGGCTTGCGCCGATACCTGAATGGCACCGACCTGGCGCAGGCAAGACA
AGCCGCAGTAGCCTGGGCCCGCTATGAGCAAAGCCTGGCGCAGCCTGGCCTGGCACCGCCCCCCTCGCCTGAACTCGATG
ATCTTGCGACGCAGGATCGCCTGGTCAGGAAATACCGGATACAAGCGCACTATTTGGCGCAGCAATGCTTTCTTGGCGAA
ACGGGCATTTTCAGTCTCATTGCCCGTTTGCCTGCGGTCCCCGTGGCCATCGTTCACGGCCAGCTGGACTGTGTGTGCCA
GCCGGAGAACGCCAGGCGCTTGCAGCAGGCGATCCCGGGGAGTCGCCTGGCATGGGCCGACGGCGCTGGCCACGATCCCT
TTCACCCGGCCATGAGCAGCGCCTGGATCGCGTTTCTGCACCACTTTTCCGAAGCGGGAAACTTCGACATTTCCGAGGCC
TGA

Upstream 100 bases:

>100_bases
AAAGCCTTCAGAAACGCCTACAGATTTTCATGATTCGACAAATTGATGCATCCCCTCATTCCCCTGCTAAGGTGCTGTTC
CCATTTCGCAAATTTCACTT

Downstream 100 bases:

>100_bases
TAAAAAATGCAGACCAGCAAAGATTGACAATACGCTCACTGCATACAATTTTTCTGTACAATCCGCCATGTTTTGGGTGC
CTTGCCTCGCGTTCGCGGGG

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MFSPLEPLRTGYLDVGDGHRLYFETCGNPRGLPVVVLHGGPGSGTSARMRTLYDPERFHTVLFDQRGCGRSLPQGELHAN
HLNALIADIERLRLHLGIARWLVSGGSWGATLALAYTANTPQAVLGILVRSVFLAGDHDIQWFFQGAKALVPQAWEAFAA
QVAPENSDLLSGLRRYLNGTDLAQARQAAVAWARYEQSLAQPGLAPPPSPELDDLATQDRLVRKYRIQAHYLAQQCFLGE
TGIFSLIARLPAVPVAIVHGQLDCVCQPENARRLQQAIPGSRLAWADGAGHDPFHPAMSSAWIAFLHHFSEAGNFDISEA

Sequences:

>Translated_320_residues
MFSPLEPLRTGYLDVGDGHRLYFETCGNPRGLPVVVLHGGPGSGTSARMRTLYDPERFHTVLFDQRGCGRSLPQGELHAN
HLNALIADIERLRLHLGIARWLVSGGSWGATLALAYTANTPQAVLGILVRSVFLAGDHDIQWFFQGAKALVPQAWEAFAA
QVAPENSDLLSGLRRYLNGTDLAQARQAAVAWARYEQSLAQPGLAPPPSPELDDLATQDRLVRKYRIQAHYLAQQCFLGE
TGIFSLIARLPAVPVAIVHGQLDCVCQPENARRLQQAIPGSRLAWADGAGHDPFHPAMSSAWIAFLHHFSEAGNFDISEA
>Mature_320_residues
MFSPLEPLRTGYLDVGDGHRLYFETCGNPRGLPVVVLHGGPGSGTSARMRTLYDPERFHTVLFDQRGCGRSLPQGELHAN
HLNALIADIERLRLHLGIARWLVSGGSWGATLALAYTANTPQAVLGILVRSVFLAGDHDIQWFFQGAKALVPQAWEAFAA
QVAPENSDLLSGLRRYLNGTDLAQARQAAVAWARYEQSLAQPGLAPPPSPELDDLATQDRLVRKYRIQAHYLAQQCFLGE
TGIFSLIARLPAVPVAIVHGQLDCVCQPENARRLQQAIPGSRLAWADGAGHDPFHPAMSSAWIAFLHHFSEAGNFDISEA

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 34937; Mature: 34937

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPLEPLRTGYLDVGDGHRLYFETCGNPRGLPVVVLHGGPGSGTSARMRTLYDPERFHT
CCCCCCHHHCCCEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHCCHHHHHH
VLFDQRGCGRSLPQGELHANHLNALIADIERLRLHLGIARWLVSGGSWGATLALAYTANT
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
PQAVLGILVRSVFLAGDHDIQWFFQGAKALVPQAWEAFAAQVAPENSDLLSGLRRYLNGT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DLAQARQAAVAWARYEQSLAQPGLAPPPSPELDDLATQDRLVRKYRIQAHYLAQQCFLGE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGIFSLIARLPAVPVAIVHGQLDCVCQPENARRLQQAIPGSRLAWADGAGHDPFHPAMSS
HHHHHHHHHCCCCCEEEEECCEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
AWIAFLHHFSEAGNFDISEA
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFSPLEPLRTGYLDVGDGHRLYFETCGNPRGLPVVVLHGGPGSGTSARMRTLYDPERFHT
CCCCCCHHHCCCEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHCCHHHHHH
VLFDQRGCGRSLPQGELHANHLNALIADIERLRLHLGIARWLVSGGSWGATLALAYTANT
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
PQAVLGILVRSVFLAGDHDIQWFFQGAKALVPQAWEAFAAQVAPENSDLLSGLRRYLNGT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DLAQARQAAVAWARYEQSLAQPGLAPPPSPELDDLATQDRLVRKYRIQAHYLAQQCFLGE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGIFSLIARLPAVPVAIVHGQLDCVCQPENARRLQQAIPGSRLAWADGAGHDPFHPAMSS
HHHHHHHHHCCCCCEEEEECCEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
AWIAFLHHFSEAGNFDISEA
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]