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The map label for this gene is nahR [H]

Identifier: 71907160

GI number: 71907160

Start: 1636506

End: 1637402

Strand: Reverse

Name: nahR [H]

Synonym: Daro_1528

Alternate gene names: 71907160

Gene position: 1637402-1636506 (Counterclockwise)

Preceding gene: 71907162

Following gene: 71907159

Centisome position: 36.38

GC content: 65.11

Gene sequence:

>897_bases
ATGTCGAGACCCGATCTGAACTTGCTGGTCACCCTTGATGTGCTGCTCGCAGAGGGCAGCGTTGCGCGCGCCGCCCGACG
CTTGCGGCTCAGCCCGTCGGCGATGAGCCGGGCGCTGGCGCGATTGCGCGAGACAACGGGCGACCCGTTGCTGGTCCGTG
CCGGACGCGGTCTCGTCCCGACGCCCCGCGCCATCGAACTACGCGAGCGAGTCGGTCAGCTCGTGCAGGATGGAGAAGCC
GTCTTGCGCCCGGCCGAAAGGCTCGATCTGAAACAACTGGTCAGGACATTTACGCTGCGCACCAGCGAAGGTTTTGTCGA
GACCTTCGGACCCGAGCTGATCGCCCGGATCAGCGAGGAAGCGCCCGGTGTGCGCCTGTGCTTTGTGCAGAAACCCGACA
AAGACAGCACCCCGCTGCGCGATGGACTCGTCGATCTGGAAACCGGCGTTGTCGGCAAGACGACAGCGCCAGAACTACGG
GTCCAGACATTGTTCCGCGACCGTTTCGTTGGCGTCGTGCGCCTGGGGCACCCGTTGAGCCGGGTTGAAATCACCCCTTC
CCGCTATGCGGCCGGCCGCCACATCTACGTCTCGCGGCGGGGACTGGGCAAGGGCGCGATTGATGAAGCGCTGAAAGCAT
TCGGACTGGAACGGCAGATCGTCACCATCGTCGGTGGCTTTTCCACCGCGCTGGCGCTGGCTCGGGCCACTGACCTGATC
GCCAGCGTTCCCGAACGACACACCGGAAACCTGCGCAGCGGAATGCATAGCTTCCCGCTTCCCGTCGCCATGCCGGAGAT
CACGGTATCCCTGCTCTGGCACCCAAGGCTGGATGCCGACCCAGCCCATCGCTGGCTGCGCGCTCATGTCAGGGATGTTT
GCGCGGCGCTCCGCTGA

Upstream 100 bases:

>100_bases
GAATCGTAGTGCCGGCTTTAGCATGGCGGAAGGCGCAGCATTTGCACTTTATTGCTGCGTTTGACGCCATATATCGATCA
AACACTGCTATGGTTGAAGC

Downstream 100 bases:

>100_bases
AGGCGGGGATTTGCAATGAACGGAAGGGATCGCTTAGGCGAGATACCAGCGCCGCGTAAGCGGATATAGCGACAGATGAC
CGCTAATCGATAAGCCCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSRPDLNLLVTLDVLLAEGSVARAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIELRERVGQLVQDGEA
VLRPAERLDLKQLVRTFTLRTSEGFVETFGPELIARISEEAPGVRLCFVQKPDKDSTPLRDGLVDLETGVVGKTTAPELR
VQTLFRDRFVGVVRLGHPLSRVEITPSRYAAGRHIYVSRRGLGKGAIDEALKAFGLERQIVTIVGGFSTALALARATDLI
ASVPERHTGNLRSGMHSFPLPVAMPEITVSLLWHPRLDADPAHRWLRAHVRDVCAALR

Sequences:

>Translated_298_residues
MSRPDLNLLVTLDVLLAEGSVARAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIELRERVGQLVQDGEA
VLRPAERLDLKQLVRTFTLRTSEGFVETFGPELIARISEEAPGVRLCFVQKPDKDSTPLRDGLVDLETGVVGKTTAPELR
VQTLFRDRFVGVVRLGHPLSRVEITPSRYAAGRHIYVSRRGLGKGAIDEALKAFGLERQIVTIVGGFSTALALARATDLI
ASVPERHTGNLRSGMHSFPLPVAMPEITVSLLWHPRLDADPAHRWLRAHVRDVCAALR
>Mature_297_residues
SRPDLNLLVTLDVLLAEGSVARAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIELRERVGQLVQDGEAV
LRPAERLDLKQLVRTFTLRTSEGFVETFGPELIARISEEAPGVRLCFVQKPDKDSTPLRDGLVDLETGVVGKTTAPELRV
QTLFRDRFVGVVRLGHPLSRVEITPSRYAAGRHIYVSRRGLGKGAIDEALKAFGLERQIVTIVGGFSTALALARATDLIA
SVPERHTGNLRSGMHSFPLPVAMPEITVSLLWHPRLDADPAHRWLRAHVRDVCAALR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=26.0586319218241, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081684, Length=300, Percent_Identity=26.3333333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081766, Length=245, Percent_Identity=26.1224489795918, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786820, Length=115, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32749; Mature: 32617

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPDLNLLVTLDVLLAEGSVARAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCEEEEEEEHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRAIELRERVGQLVQDGEAVLRPAERLDLKQLVRTFTLRTSEGFVETFGPELIARISEE
CCHHHHHHHHHHHHHHCCHHHHCCHHHCCHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHC
APGVRLCFVQKPDKDSTPLRDGLVDLETGVVGKTTAPELRVQTLFRDRFVGVVRLGHPLS
CCCEEEEEEECCCCCCCCHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
RVEITPSRYAAGRHIYVSRRGLGKGAIDEALKAFGLERQIVTIVGGFSTALALARATDLI
HEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
ASVPERHTGNLRSGMHSFPLPVAMPEITVSLLWHPRLDADPAHRWLRAHVRDVCAALR
HHCCCCCCCCHHCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRPDLNLLVTLDVLLAEGSVARAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCEEEEEEEHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRAIELRERVGQLVQDGEAVLRPAERLDLKQLVRTFTLRTSEGFVETFGPELIARISEE
CCHHHHHHHHHHHHHHCCHHHHCCHHHCCHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHC
APGVRLCFVQKPDKDSTPLRDGLVDLETGVVGKTTAPELRVQTLFRDRFVGVVRLGHPLS
CCCEEEEEEECCCCCCCCHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
RVEITPSRYAAGRHIYVSRRGLGKGAIDEALKAFGLERQIVTIVGGFSTALALARATDLI
HEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
ASVPERHTGNLRSGMHSFPLPVAMPEITVSLLWHPRLDADPAHRWLRAHVRDVCAALR
HHCCCCCCCCHHCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]