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The map label for this gene is dhaR [H]

Identifier: 71907159

GI number: 71907159

Start: 1635537

End: 1636175

Strand: Reverse

Name: dhaR [H]

Synonym: Daro_1527

Alternate gene names: 71907159

Gene position: 1636175-1635537 (Counterclockwise)

Preceding gene: 71907160

Following gene: 71907158

Centisome position: 36.35

GC content: 53.21

Gene sequence:

>639_bases
ATGGAAACTCAGCTTTCAACTCCCCGTAGGCGTGGCCGACCACCCAAACCCAGAGAGTATTTGGTTGAAACACGTGATTT
GTTGCTGCGCGCCGGCTTGGAAGTTCTGACCGAGAAAGGTTTCTCGGCCACAGGCATTGACGAAATCTTGCACCGTGTCA
GCGTTCCGAAAGGGTCTTTCTATCATTACTTTGAAAGCAAAGAGGCATTCGGTGCAGCGTTAATTGCGCAATATGCTCAT
TTTTTTGCTCGCAAGATTGACCATTATCTCAGCGACAAAACCATCTCTCCGCTCGCGCGTTTACGCGCTTTCGTAGCCGG
AGCTCAAGCCGGCATGGCTCGTCACGATTTTCGGCGCGGCTGCCTCATCGGAAATCTGGGTCAGGAAATGGGCTCCCTCC
CAGAAAGCTTCCGCAGGCAGTTGCAAGCGGTTTTCGACGATTGGCAGTCAAGATTTGCGCGTTGCCTGATGGCAGCTCAA
GAAGCTGGCGAGCTTTCACGGCAAGCCGATTGTGAACAACTCGCTGCTTTTTTCTGGATTGGCTGGGAGGGTGCGGTGCT
GAGGGCGAAGTTGGAACAAAGCGCAGAGCCGCTTGAAGTTTTTGCACGAGGTTTTTTTGCTGGGTTACCCCCCGGCTAA

Upstream 100 bases:

>100_bases
TCGGTTTCTGCGGCAAAGTGAGCTAACGCCTCCAGCGCCAAGAACTGGCCTACTTAAAAGTTACTTGATTTAATGAGACG
GTCGGTCTAATATAAAAAAC

Downstream 100 bases:

>100_bases
TTTTTTTGCCTTTTACTAGACGTTCGGTCTAAATTACCAAGGAGACTCACATGTTCAAAGGGATTTTGATTGAGAAGGAC
GAATCCGGTTACCGCGCTGG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
METQLSTPRRRGRPPKPREYLVETRDLLLRAGLEVLTEKGFSATGIDEILHRVSVPKGSFYHYFESKEAFGAALIAQYAH
FFARKIDHYLSDKTISPLARLRAFVAGAQAGMARHDFRRGCLIGNLGQEMGSLPESFRRQLQAVFDDWQSRFARCLMAAQ
EAGELSRQADCEQLAAFFWIGWEGAVLRAKLEQSAEPLEVFARGFFAGLPPG

Sequences:

>Translated_212_residues
METQLSTPRRRGRPPKPREYLVETRDLLLRAGLEVLTEKGFSATGIDEILHRVSVPKGSFYHYFESKEAFGAALIAQYAH
FFARKIDHYLSDKTISPLARLRAFVAGAQAGMARHDFRRGCLIGNLGQEMGSLPESFRRQLQAVFDDWQSRFARCLMAAQ
EAGELSRQADCEQLAAFFWIGWEGAVLRAKLEQSAEPLEVFARGFFAGLPPG
>Mature_212_residues
METQLSTPRRRGRPPKPREYLVETRDLLLRAGLEVLTEKGFSATGIDEILHRVSVPKGSFYHYFESKEAFGAALIAQYAH
FFARKIDHYLSDKTISPLARLRAFVAGAQAGMARHDFRRGCLIGNLGQEMGSLPESFRRQLQAVFDDWQSRFARCLMAAQ
EAGELSRQADCEQLAAFFWIGWEGAVLRAKLEQSAEPLEVFARGFFAGLPPG

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=177, Percent_Identity=31.0734463276836, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23841; Mature: 23841

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQLSTPRRRGRPPKPREYLVETRDLLLRAGLEVLTEKGFSATGIDEILHRVSVPKGSF
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCH
YHYFESKEAFGAALIAQYAHFFARKIDHYLSDKTISPLARLRAFVAGAQAGMARHDFRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
CLIGNLGQEMGSLPESFRRQLQAVFDDWQSRFARCLMAAQEAGELSRQADCEQLAAFFWI
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWEGAVLRAKLEQSAEPLEVFARGFFAGLPPG
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METQLSTPRRRGRPPKPREYLVETRDLLLRAGLEVLTEKGFSATGIDEILHRVSVPKGSF
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCH
YHYFESKEAFGAALIAQYAHFFARKIDHYLSDKTISPLARLRAFVAGAQAGMARHDFRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
CLIGNLGQEMGSLPESFRRQLQAVFDDWQSRFARCLMAAQEAGELSRQADCEQLAAFFWI
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWEGAVLRAKLEQSAEPLEVFARGFFAGLPPG
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]