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The map label for this gene is ctaD [H]

Identifier: 71907102

GI number: 71907102

Start: 1592355

End: 1593950

Strand: Reverse

Name: ctaD [H]

Synonym: Daro_1470

Alternate gene names: 71907102

Gene position: 1593950-1592355 (Counterclockwise)

Preceding gene: 71907103

Following gene: 71907101

Centisome position: 35.41

GC content: 63.85

Gene sequence:

>1596_bases
ATGAGCCTCGCCACCACCCATCCTGCCGCCCACCCCGAGCACCACGAGCCGACCGGCCTGCTGCGCTGGCTGACGACGAC
GAATCACAAGGACATCGGCACGATGTACCTGACTTTCTCGCTGATCATGTTCTTCGTCGGCGGCCTGATGATCCTCGCCG
TGCGCGCCGAACTGTTCCAGCCCGGCTTGCAGTTGATGAAGCCGGAGTTCTTCAACCAGCTGATCGGCGTGCATGCGCTG
GTCATGATCTTCGCGGCGCTGATGCCGGCCGCCACCGGCTTCGCCAACTGGATGATCCCGCTGATGATCGGCGCCCCGGA
CATGGCGCTGCCGCGGCTGAACAACTGGGGCTTCTGGCTGCTGCCGCCGGCCGCCATCCTGCTCACCCTGCCCTTCTCGC
TGGCGCTGTTCGGCATCGGTGACGGGGCACTGGCCACCGGCTGGACCTTCTATGCGCCGCTCTCGGTGCAGGGCGGCATG
GGCGTCGATTTCGCCATCCTCGCCGTGCATATCCTCGGCATCTCGTCGATCATGGGCTCGATCAACATCATCGTCACCAT
CTTCAACATGCGGGCGCCGGGCATGACCATGATGAAGCTGCCGCTCTTCTGCTGGGGCTGGCTGATCACCGCTTTCCTGC
TGATCGCCACGCTGCCGGTACTGGCCGGCGCGGTGACCATGCTGCTGACCGACCGTCATTTCGGCACCCATTTCTTCGAT
GCGGCCGGCGGCGGCGACCCCATCCTCTTCCAGCACCTGTTCTGGTTCTTCGGCCATCCCGAGGTGTACATCCTGCTGCT
GCCGGTGTGGGGGCTGATGCCGCACGTGCTGTCCACCTTCTCGCGCAAGCCGACCTACGGCTACACGGCGCAGGTCTACA
GCTTCATCGCCATCGGCATCCTGTCGGTGGTGGTCTGGGCCCACCATTTCTTCACCGCCGGCATGCCGGTGCCGGCCCTG
ATCTACTTCATGTTCAGCACCATGGCCATCTCGCTGCCGCTGGCCGTGCTCTTCTTCTGCTGGATCGCCACCATGTGGAA
AGGGGCGATGACGTTCGAGACGCCGATGCTGTTCGCCGTCGGCTTCATCGTCCTGTTCGGCATCGCCGGCCTGACCGGGC
TGATCCTCGCCGACGTGGCGGCCGACGCCCAGTACCACCACAGCTACTTCGTCGTCGCCCACTTCCACTACGCGCTGTTC
GCCGGCGGCATCATGGGCGTGATGACCGGGGTCTATTACTGGCTGCCCAAATGGACCGGCCACATGTACAACGAAACGCT
GGGCAAGCTGCATTTCTGGCTGACCGTCGTTTCCTTCAACCTGACCTTCATTCCGCAATTCTTCCTCGGTCTGGCCGGCA
TGCCGCGACGCATCCCGGACTACGCCCTGCAGTTCGCCGAATTCAATGCGATCTCGACCATCGGGGCCTTCATCCTCGGT
CTCAGCCAGCTGCTCTTCGCCTGGAACATCTGGTCCTGCACCCGGGGCGGCCCGAAGGTCGAGAACCGTGTCTGGGAGGG
AGCCGACGGGCTGGAATGGGAACTGTCTTCGCCGCCGCCTCACCATAGCTGGGAAACCCAGCCCCAGGTCAAATGA

Upstream 100 bases:

>100_bases
CTGGCCGGCATCATCACTTACGAACGCAACAGTTTCGGCAACCAGATGGGCGACATGATCCAGCCCGCCCAGATCAAGGC
CCTGCGCTAGGAGAACCGAG

Downstream 100 bases:

>100_bases
GAGAGGCCAACATGCAAGCCGGATTTTCCGAAGCCGATCTCGAACGTCGCCGCAGCGCATCCCGGCGGCTGGCCTGGCTG
CTCGGCGCCATCGTGCTCGC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSLATTHPAAHPEHHEPTGLLRWLTTTNHKDIGTMYLTFSLIMFFVGGLMILAVRAELFQPGLQLMKPEFFNQLIGVHAL
VMIFAALMPAATGFANWMIPLMIGAPDMALPRLNNWGFWLLPPAAILLTLPFSLALFGIGDGALATGWTFYAPLSVQGGM
GVDFAILAVHILGISSIMGSINIIVTIFNMRAPGMTMMKLPLFCWGWLITAFLLIATLPVLAGAVTMLLTDRHFGTHFFD
AAGGGDPILFQHLFWFFGHPEVYILLLPVWGLMPHVLSTFSRKPTYGYTAQVYSFIAIGILSVVVWAHHFFTAGMPVPAL
IYFMFSTMAISLPLAVLFFCWIATMWKGAMTFETPMLFAVGFIVLFGIAGLTGLILADVAADAQYHHSYFVVAHFHYALF
AGGIMGVMTGVYYWLPKWTGHMYNETLGKLHFWLTVVSFNLTFIPQFFLGLAGMPRRIPDYALQFAEFNAISTIGAFILG
LSQLLFAWNIWSCTRGGPKVENRVWEGADGLEWELSSPPPHHSWETQPQVK

Sequences:

>Translated_531_residues
MSLATTHPAAHPEHHEPTGLLRWLTTTNHKDIGTMYLTFSLIMFFVGGLMILAVRAELFQPGLQLMKPEFFNQLIGVHAL
VMIFAALMPAATGFANWMIPLMIGAPDMALPRLNNWGFWLLPPAAILLTLPFSLALFGIGDGALATGWTFYAPLSVQGGM
GVDFAILAVHILGISSIMGSINIIVTIFNMRAPGMTMMKLPLFCWGWLITAFLLIATLPVLAGAVTMLLTDRHFGTHFFD
AAGGGDPILFQHLFWFFGHPEVYILLLPVWGLMPHVLSTFSRKPTYGYTAQVYSFIAIGILSVVVWAHHFFTAGMPVPAL
IYFMFSTMAISLPLAVLFFCWIATMWKGAMTFETPMLFAVGFIVLFGIAGLTGLILADVAADAQYHHSYFVVAHFHYALF
AGGIMGVMTGVYYWLPKWTGHMYNETLGKLHFWLTVVSFNLTFIPQFFLGLAGMPRRIPDYALQFAEFNAISTIGAFILG
LSQLLFAWNIWSCTRGGPKVENRVWEGADGLEWELSSPPPHHSWETQPQVK
>Mature_530_residues
SLATTHPAAHPEHHEPTGLLRWLTTTNHKDIGTMYLTFSLIMFFVGGLMILAVRAELFQPGLQLMKPEFFNQLIGVHALV
MIFAALMPAATGFANWMIPLMIGAPDMALPRLNNWGFWLLPPAAILLTLPFSLALFGIGDGALATGWTFYAPLSVQGGMG
VDFAILAVHILGISSIMGSINIIVTIFNMRAPGMTMMKLPLFCWGWLITAFLLIATLPVLAGAVTMLLTDRHFGTHFFDA
AGGGDPILFQHLFWFFGHPEVYILLLPVWGLMPHVLSTFSRKPTYGYTAQVYSFIAIGILSVVVWAHHFFTAGMPVPALI
YFMFSTMAISLPLAVLFFCWIATMWKGAMTFETPMLFAVGFIVLFGIAGLTGLILADVAADAQYHHSYFVVAHFHYALFA
GGIMGVMTGVYYWLPKWTGHMYNETLGKLHFWLTVVSFNLTFIPQFFLGLAGMPRRIPDYALQFAEFNAISTIGAFILGL
SQLLFAWNIWSCTRGGPKVENRVWEGADGLEWELSSPPPHHSWETQPQVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=515, Percent_Identity=46.7961165048544, Blast_Score=423, Evalue=1e-118,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=38.2239382239382, Blast_Score=350, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=44.87895716946, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=48.3180428134557, Blast_Score=290, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6226523, Length=258, Percent_Identity=46.8992248062016, Blast_Score=199, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58913; Mature: 58781

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLATTHPAAHPEHHEPTGLLRWLTTTNHKDIGTMYLTFSLIMFFVGGLMILAVRAELFQ
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGLQLMKPEFFNQLIGVHALVMIFAALMPAATGFANWMIPLMIGAPDMALPRLNNWGFWL
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEE
LPPAAILLTLPFSLALFGIGDGALATGWTFYAPLSVQGGMGVDFAILAVHILGISSIMGS
CCHHHHHHHHHHHHHHHCCCCCCHHCCEEEEECEEECCCCCCHHHHHHHHHHHHHHHHCC
INIIVTIFNMRAPGMTMMKLPLFCWGWLITAFLLIATLPVLAGAVTMLLTDRHFGTHFFD
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCC
AAGGGDPILFQHLFWFFGHPEVYILLLPVWGLMPHVLSTFSRKPTYGYTAQVYSFIAIGI
CCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LSVVVWAHHFFTAGMPVPALIYFMFSTMAISLPLAVLFFCWIATMWKGAMTFETPMLFAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
GFIVLFGIAGLTGLILADVAADAQYHHSYFVVAHFHYALFAGGIMGVMTGVYYWLPKWTG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HMYNETLGKLHFWLTVVSFNLTFIPQFFLGLAGMPRRIPDYALQFAEFNAISTIGAFILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSQLLFAWNIWSCTRGGPKVENRVWEGADGLEWELSSPPPHHSWETQPQVK
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLATTHPAAHPEHHEPTGLLRWLTTTNHKDIGTMYLTFSLIMFFVGGLMILAVRAELFQ
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGLQLMKPEFFNQLIGVHALVMIFAALMPAATGFANWMIPLMIGAPDMALPRLNNWGFWL
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEE
LPPAAILLTLPFSLALFGIGDGALATGWTFYAPLSVQGGMGVDFAILAVHILGISSIMGS
CCHHHHHHHHHHHHHHHCCCCCCHHCCEEEEECEEECCCCCCHHHHHHHHHHHHHHHHCC
INIIVTIFNMRAPGMTMMKLPLFCWGWLITAFLLIATLPVLAGAVTMLLTDRHFGTHFFD
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCC
AAGGGDPILFQHLFWFFGHPEVYILLLPVWGLMPHVLSTFSRKPTYGYTAQVYSFIAIGI
CCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LSVVVWAHHFFTAGMPVPALIYFMFSTMAISLPLAVLFFCWIATMWKGAMTFETPMLFAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
GFIVLFGIAGLTGLILADVAADAQYHHSYFVVAHFHYALFAGGIMGVMTGVYYWLPKWTG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HMYNETLGKLHFWLTVVSFNLTFIPQFFLGLAGMPRRIPDYALQFAEFNAISTIGAFILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSQLLFAWNIWSCTRGGPKVENRVWEGADGLEWELSSPPPHHSWETQPQVK
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]